Hi, I have been on a very low dose of bisoprolol.1.25mg for about 8 months now, but recently my palpitations have gotten worse, and my GP has increased my dose to 2.5mg. I have been to specialist, and although I do have an irregular heart beat, he said my heart was fine, that was several months ago. I am trying the new dose, hoping it helps, because the episodes are getting worse, when out walking, or really any activity, just going into the kitchen, will trigger the palpitations. I live in the UK now, but was first seen in the US for the problem several years ago, and was told I could not have Beta Blockers because my heart was already too low at sleep times. I did have a monitor for 24 hours then, and have had one here a few months back, and the doc here said I would be fine on them..hmmm, this is getting a bit scary!! I have only just started the higher dose..can anyone tell me what I can expect?? It used to be that the episodes would last a few seconds maybe several times a week..now they seem to be constant, until I sit and rest, it is very uncomfortable, and I get short of breath. I am really hoping the meds help, can't go on like this.