I have had lots of heartburn and problems laying in bed with the feeling someone was pushing on my chest around the top of my stomach. My doctor requested I use omeprazole daily and not just temporary. After several months my whole digestive system changed. After 50+ years of regular bowel movement I started to get a little bound up and it seems like things don't move down thru my intestines like they use to. I have to use aids to soften my stool. I have quit using omeprazole and put up with the H/B, however I still have a different digestive sys. Previously I used to have loose stools ocassionally but not anymore. Could omeprazole caused all this?