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Avatar universal

Best Treatment for HBv

I am 53 years old last month I have went for preventive health check up and based on the report findings the followings noted; SGOT 83 IU/L ,SGPT 200 IU/L , Doctor recmended me to see the Gastro.consultant , the gastro.consultant advised me to go for others test the result are as follows: Anti-dsDNA 16.6 IU/ml. , HBsAg test value 9520(Reactive) ,HCV,IgG test value 0.12 ( non Reactive) ,Anti Nuclear Antibody ( ANA) 0.12 , Immunoglobulin IgA 279 mg/dl , Tissue Transglutaminase antibody IgA 0.40 U/mL , Anti Mitochondrial Antibody , Serum 0.26 UL/ml , ASMA 2.70 U/mL , LKM Antibody 0.02 U/ml , Hepatitis B envelope Antibody test value (Ab) 43.0 ( Reactive) , Hapatitis Be Antigen ( HBeAg) 0.15 ( Non reactive),AFP 4.38ng/ml  , HBV DNA Quantitative,Real Time PCR 5156250 IU/ml. Based on this the Doctor advised me for the treatment  Tab.Entavir 0.5 mg one daily. Here i went for second opinion with Lever specialist consultant and he advised me to go for Fibroscan which the result is 5.91 Kpa ( Negative for fibrosis).Now the lever specialist advised for Viraferon Peg 80 mg once in a week and monitor CBC & S creatin every 15 days.I have not started the treatment yet as I am going out of India for 1.5 months as Doctor told me that this treatment will be given under there supervision , please suggest which treatment is suitable under these report.Also with vaccine this problem will be solved and how long i have to take this treatment.
170 Responses
Avatar universal
http://www.sanihelp.it/esami/118/calciuria.html

tests are not bad, all normal, only urine calcium is high, check that page and try to translate from italian, there are many diseases making high calcium and your doctor should have checked them all because one thing we know for sure there is something wrong with pth, calcium and vit d

Avatar universal
Thank you so much ,
Avatar universal
I was looking for clues on vit d toxicity and found this info about people supersensitive to vit d despite low levels, from their hypothesis/experience it is an unbalance with vit A fro cod liver oil.carlson is a brand with vit a from cod liver oil at doses of 10.000iu or 25.000iu.it is good with bottles with monthly pill supply, the big supply bottle has soy that can be gmo so avoid it

http://www.westonaprice.org/blogs/cmasterjohn/is-vitamin-d-safe-still-depends-on-vitamins-a-and-k-testimonials-and-a-human-study/

Try and let us know if vit a makes calcium normal by fe weeks
Avatar universal
Hello Stef Sir...
Last year during blood donation in dec 2014 i found out dat i am hbsag +ve.
I went to the drs in delhi but hvnt got satisfactory answers.Right now i feel normal but i am worried about my future.
M not married and i have left alcohol an year back.
my reports are...

1.HBV DNA -            not detected , initially in dec 2014 - 40 Iu/ml

2.Hbsag QUANT.-     now 8126, initially in dec 2014 - 14070 Iu/ml

3.fibroscan-              5.4 kpa

4.alpha feto protein-  2.79 ng/ml

5.ALT-                     44 now

6.HbeAg -                -ve

7.anti Hbe -             +ve

8.Ultrasound -          Normal

9.Total protein -         8.1

10.Mean normal prothrombin time - 11.10

11.Prothrombin ratio - 1.11

12.Anti HAV -           +VE

MY QUESTIONS ARE-

1. If i was infected recently or since childhood.My brother is Hbsag -ve.

2. I am 24 years old now.Can you please tell how many years approximately I will live.

3. I am non alcoholic.I smoke 1-2 ciggs max.

4. what food shuld i eat,any specific kind or anything with less fat and hygenic.

5. In wat interval i need to go for the tests.
6.Do i need to worry much.I mean can i live d way i was before.

Please help sir.
Since i have came to knw this I am not able to live fully.I have became anxious,depressive and not happy at all.
Ur valuable suggestions can help me.
PLEASE HAVE AN EYE OVER THE ISSUE SIR.
Avatar universal
Dont worry you are perfectly healthy, you can wait for hbsag to becone lower on its own and use peginterfero  to clear hbsag when it reaches less than 1000iu ml

check hbvdna, liver function, fibroscan every year.if hbvdna becomes elevated or fibroscan start tenofovir
ulrasound evry 6 months
hbsag quantevery year

eat fresh and organic, no smoke, take vit d3 supplements 5000 to 10.000u daily
Avatar universal
Hi Stef
Hope you are doing good ,
As I discussed earlier post that my Dr.Endocrinology recommended to stop Vit.D3 supplement for some time due to elevated level of Serum Clcium and 24 hors urine - calcium & Phosphorus. Today I did the test and the result are as follows:Calcium, Serum:

Date 8 .8. 2015: Calcium serum: 10.40 mg/dL

- on 23 Feb.2015: 10.60 mg/dL ( Ref.range 8.8 - 10.60)
-on 7 March 2015: 10.50 mg/dL .
-on 3 April 2015: 10.50 mg/dL.
- on 1 may 2015: 11.20 mg/dL.    
-On 10 may 2015: 9.6mg/dl.      
-On 13/6/2015 : 9.8 mg/dl.

24 hours urine test result:
Date 8.8.2015: 303mg/day ( Ref.range 100-300 )
- 156/6/2015 : 375 mg/day.

Phosphorus,24-Hour Urine :
Date 8.8.2105 : 737.3 mg/day ( Ref.range 400-1300)
- 15.6.2015 : 825 mg/day.


Vitamin D,25 Hydroxy:
- on 8 Nov.2013 : Vitamin D , 25 - Hydroxy ,Serum ( CLIA ) 41.05 nmol/L.
- on 22 June 2014Vitd25oh :18.22 ng/ml.
- on 24/8/2014 : 51 ng/ml.
- on 8 Nov.2014 : 51.2 ng/ml.
- on 5 Feb.2015 : 157.55 nmol/L ( Sufficient range 75-250 nmol/L )
- on 7 march 2015 : 164.50 nmol/L (CLIA method) Range 75-250 sufficient)
- on 3 April 2015: 174.12 nmol/L ( CLIA method - Ref.renge 75-250 sufficient )
- on 1 May 2015 : 65.2 ng/ml
- On 13/6/2015: 41.1ng/ml
- On 8/8/2015: 26.01 ng/ml ( Insufficient range)

PTH ( Parathyroid Hormone) Intact, Serum :
- on 5 Feb.2015 : 73 pg/mL ( Ref.Interval 14 - 72 )
-on 7 March 2015: 86.60 pg/mL ( CLIA method Ref.range 14-72 )
-on 3 April 2015: 73.60 pg/mL.
- On 1 May 2015: 83.80 pg/mL.
-On 13/6/15: 63.45 pg/ml.
-On 8/8/2015: 95.40 pg/mL. ( HIGH)

S.Creatinine:
-On  10 May 2015: S.creatinine : 1.4 mg/dl.
-On 13/6/2015: S.creatinine : 1.09 mg/dl (HIGH)
-On 8/8/2015: 1.00 mg/dL

L.F.T.-

- 28 Jan.2014
SGOT / AST 48 U/L.
SGPT / ALT - 106 U/L.
ALK . Phosphatase - 139 U/L.

L.F.T.-
-  27/4/2014-
SGOT / AST 40 U/L.
SGPT / ALT  65 U/L.
Alkaline Phosphatase ( ALP ) 143 U/L.

L.F.T :
9 August 2014:

Serum billrubin total ( Jendrassik- Grof) 0.8 mg/dl ,
Serum Billrubin direct ( Jendrassik - Grof) 0.1 mg/dl,
Serum Billirubin Indirect 0.70 mg/dl ,
AST/SGOT ( kinetic-Henry) 10 IU/L  ,
ALT / SGPT ( kinetic-Henry) 26 IU/L ,
Serum Alkaline Phosphatase ( Kinetic) 110 IU/L ,
GGT 22 IU/L , S.total Protein ( Bluret) 7.3g/dl ,
S.Albumin 4.1 g/dL ,
S.Globulin 3.20g/dL ,
A\G Ratio 1.28.

L.F.T
- on 8 Nov.2014:
Serum Biluirubin indirect 0.50 mg/dl ,
AST/SGPT ( kinetic - Henry) 24 IU/L. ,
ALT/SGPT ( Kinetic Henry) 34 IU/L. ,
Serum Alkaline Phosphatase ( Kinetic) 136 * High  IU/L. ,
GGT 17 IU/L. ,
S.total protein 7.8 g/dl. ,
S.Albumin 4.1 g/dl. ,
S.Globulin 3.70*High g/dl ,
A\G Ratio 1.11* Low.

LFT: On 25Jan.2015:
SGOT/AST:  12.8IU/L ( Ref.range 0.0 -37.0)
SGPT/ALT : 24.7 IU/L ( Ref.range 0-41 )

LFT : On 20 Fe.2015:
ALT : 26 IU/L ( Ref.Range 10-40)
Serum Alkaline Phosphatase 112* High IU/L ( Ref.Range 32-92)
GGT : 21 IU/L ( Ref.Range 7- 64)

LFT On 13/6/2015:
ALT 32 IU/L.
AST 19 IU/L.
Serum Alkaline Phosphatase 104 IU/L ( HIGH)
A|G ratio 1.34 (LOW)
GGT 17 IU/L.

LFT on 8/8/2015:
AST: 22 U/L.
ALT: 30 U/L.
GGTP: 22 U/L.
Alkaline Phosphatase ( ALP): 143 U/L.
Phosphorus: 2.00 mg/dL.

On todays report I noticed that my Vit D3 declining and PTH increasing , also I noted that my ALP always on high side and Phosphorus on LOW side.
I have not taken vit D3 supplement almost 6 weeks now, i will consult Doctor soon and ask him about the Vit D3 as well as PTH.
Looks like my calcium both on serum and 24 hours urine in line with the reference range.
Please look into all these test report and suggest ,

Thank you,
Avatar universal
TrY the combo of vit A from cod liver oil 10.000iu daily and vit k2 mk7 200mcg daily and see  if calcium declines even more, stay at least 3-6months away from vit d and ifthis combo works protecting you may restart vit d to keep at least min sufficiency
Avatar universal
Thank you Stef for your revert,
I was looking in the website and you also suggested some time back milk thistle now it is available ULTRA THISTLE 360 mg. what is your say on it?
As suggested by you i will go for vit A from cod liver oil , i am already taking vit k2 mk7 100mcg last 6 month. which is the best time to take this combo.
I was thinking to bring back the Vit D3 to sufficient level , if i take 60K vitmin D3 weekly it helps need your clarification.As you may have noted my PTH is very high beyond the range in this way i can bring down the PTH as well.
Looking fowar your suggestion as always,

Thank you,  
Avatar universal
what is your say on it?

i know it helps with liver fibrosis, dont know if it has ny effect on kidneys


which is the best time to take this combo.

now to see if calcium goes down fast


I was thinking to bring back the Vit D3 to sufficient level

not now, bring calcium down fisrt
Avatar universal
Thanks Stef ,
Shall try to bring down the calcium first and then planned for Vit.D3 and Ultra Thistle.
Avatar universal
You are about to complete 2yrs of tdf treatment. U can try IFN now. Is it sure that hbsag will go down to 1500iu after 2-3yrs of tdf. IFN must be tried in young age and works different in different individuals.
Avatar universal
I will be going 3 years with teravir then may be plan for IFN, aagin depends upon the result & Doctor opinion.
Avatar universal

Hi Stef
Its long time , hope this note will find you in good health ,
I have gone through some test , please find the report along with the previous one , some of the result had increased a lot , please give your expert opinion .


Vitamin D,25 Hydroxy:

- on 10/10/2015 : 44.6 ng/ml.
- on 8 Nov.2013 : Vitamin D , 25 - Hydroxy ,Serum ( CLIA ) 41.05 nmol/L.
- on 22 June 2014Vitd25oh :18.22 ng/ml.
- on 24/8/2014 : 51 ng/ml.
- on 8 Nov.2014 : 51.2 ng/ml.
- on 5 Feb.2015 : 157.55 nmol/L ( Sufficient range 75-250 nmol/L )
- on 7 march 2015 : 164.50 nmol/L (CLIA method) Range 75-250 sufficient)
- on 3 April 2015: 174.12 nmol/L ( CLIA method - Ref.renge 75-250 sufficient )
- on 1 May 2015 : 65.2 ng/ml
- On 13/6/2015: 41.1ng/ml
- On 8/8/2015: 26.01 ng/ml ( Insufficient range)

PTH ( Parathyroid Hormone) Intact, Serum :

- on 10/10/2015 : 89.5* H pg/ml.
- on 5 Feb.2015 : 73 pg/mL ( Ref.Interval 14 - 72 )
-on 7 March 2015: 86.60 pg/mL ( CLIA method Ref.range 14-72 )
-on 3 April 2015: 73.60 pg/mL.
- On 1 May 2015: 83.80 pg/mL.
-On 13/6/15: 63.45 pg/ml.
-On 8/8/2015: 95.40 pg/mL. ( HIGH)

S.Creatinine:

- On 10/10/2015 : 0.90 mg/dl.
-On  10 May 2015: S.creatinine : 1.4 mg/dl.
-On 13/6/2015: S.creatinine : 1.09 mg/dl (HIGH)
-On 8/8/2015: 1.00 mg/dL

L.F.T.-

- On 10/10/2015:

AST/SGOT: 29 IU/L.
ALT/SGPT : 43* H IU/L.
Serum Alkaline Phosphatase: 115* H IU/L.
GGT: 19 IU/L
A\G Ratio: 1.46* L

- 28 Jan.2014
SGOT / AST 48 U/L.
SGPT / ALT - 106 U/L.
ALK . Phosphatase - 139 U/L.

L.F.T.-
-  27/4/2014-
SGOT / AST 40 U/L.
SGPT / ALT  65 U/L.
Alkaline Phosphatase ( ALP ) 143 U/L.

L.F.T :
9 August 2014:

Serum billrubin total ( Jendrassik- Grof) 0.8 mg/dl ,
Serum Billrubin direct ( Jendrassik - Grof) 0.1 mg/dl,
Serum Billirubin Indirect 0.70 mg/dl ,
AST/SGOT ( kinetic-Henry) 10 IU/L  ,
ALT / SGPT ( kinetic-Henry) 26 IU/L ,
Serum Alkaline Phosphatase ( Kinetic) 110 IU/L ,
GGT 22 IU/L , S.total Protein ( Bluret) 7.3g/dl ,
S.Albumin 4.1 g/dL ,
S.Globulin 3.20g/dL ,
A\G Ratio 1.28.

L.F.T
- on 8 Nov.2014:
Serum Biluirubin indirect 0.50 mg/dl ,
AST/SGPT ( kinetic - Henry) 24 IU/L. ,
ALT/SGPT ( Kinetic Henry) 34 IU/L. ,
Serum Alkaline Phosphatase ( Kinetic) 136 * High  IU/L. ,
GGT 17 IU/L. ,
S.total protein 7.8 g/dl. ,
S.Albumin 4.1 g/dl. ,
S.Globulin 3.70*High g/dl ,
A\G Ratio 1.11* Low.

LFT: On 25Jan.2015:
SGOT/AST:  12.8IU/L ( Ref.range 0.0 -37.0)
SGPT/ALT : 24.7 IU/L ( Ref.range 0-41 )

LFT : On 20 Fe.2015:
ALT : 26 IU/L ( Ref.Range 10-40)
Serum Alkaline Phosphatase 112* High IU/L ( Ref.Range 32-92)
GGT : 21 IU/L ( Ref.Range 7- 64)

LFT On 13/6/2015:
ALT 32 IU/L.
AST 19 IU/L.
Serum Alkaline Phosphatase 104 IU/L ( HIGH)
A|G ratio 1.34 (LOW)
GGT 17 IU/L.

LFT on 8/8/2015:
AST: 22 U/L.
ALT: 30 U/L.
GGTP: 22 U/L.
Alkaline Phosphatase ( ALP): 143 U/L.
Phosphorus: 2.00 mg/dL.

HBV DNA Quantitative , Real time PCR : Plasma
- on 28 Jan.2014- 5156250 IU/mL.
- 1 May 2014:  - 33181 IU/mL.

- 9 August 2014: = 5.72x10^2 IU/ml.

- 8 Nov. 2014: 47.5 IU/ml.
- 20 Feb.2015 : 6.04 IU/mi.
- 13/6/2016: HBV DNA NOT DETECTED.

HBsAg Quantitative:

- On 10/10/2015: 6858 IU/ml.

- on 28 Jan. 2014:  : 7767.68 IU/mL.

- on - 1 May 2014:  6812.40 IU/m

- 9 August 2014: 3585 IU/ml.

8-  Nov.2014: 4633 IU/ml

- 20 Feb.2015 : 5174 IU/ml.
- 13/6/2015: 5431 IU/ml

FibroScan:

- On 10/10/2015: 3.8 (E kpa) , CAP ( dB/m) 272.
On 26 Dec.2014 : 4.7.
On 9 August 2014 : 4.9.
on 13/6/2015: CAP ( dbm) Median 270 , IQR 21. , E(kpa) Median 3.5 , IQR 0.5 , IQR/med 14%

I noted that the ALT  , PTH & HBsAg result had fluctuated a lot from the previous report , please let me know the reasons.

24 hrs urine & serum test is due for next week , i will share with you the result latter.

Thank you,
1 Comments
You have fantastic results, except ALT being raised and your liver seems to be fatty (CAP score). You need to take care of your diet and eating habits, and probably also exercise more to lose the fatty liver.
Avatar universal
i think alt and hbsag are not so important now we need to understand why you have problems with vitamin d pathways (severe vit d deficiency confirmed by abnormally high pth which is usually named secondary hyperparathiroidism but this has to do with vit d deficiency or some kidneys issues).what did the doctor say about this?any clue about the disease?

did you try vitamin A supplements the natural type from fish oil?carlson, nordic naturals are very good brands but also nowfoods although they dont have ifos certification
Avatar universal
another thing doctors should consider is possible kidneys damage from hbv but this is very hard to see from the tests only by using antivirals you may see improvements in creatinine clearance and serum creatinine after 1 year therapy
Avatar universal
Thanks Stef ,

I have stopped taking Vit.3 supplement as my calcium level both in serum & 24 hours urine was high so the vit D3 was stopped almost 3 months , now i have started weekly 60K as per doctor advice , and it showed increase in the result but PTH way high ,
24 /10/15 I am going for calcium check both in serum & urine then will see the result and increase the Vit D3 dose.
I also checked the Parathyroid and found no tumor its normal report.
If my calcium level within normal range i will increase the Vit D3. What you suggest how much Vit D3 should take.
Stef one more question i noticed upper back ach gone through the MRI found all normal but some time the pain is quite severe , it could be related to Vit D diffiency also .
I also lost 10 Kg.weight within 12 months, is it normal or related to HBV .I am concerned on it, please suggest as i am taking overseas job effective 25 Dec.2015 , in Maldives if health permit me i will join there.
My last meeting with Doctor advised me to eat healthy food as normal diet no restriction to any food product.
I am meeting with Doctor next week .
Avatar universal
Thank you Aduiski ,
Yes I am eating healthy diet and takes green tea 2 times on daily basis. I treatment 1 tab.of Tiravir daily after dinner and it has been started since Jan.2014 so almost 2 years now, Doctor advised to continue it further.
I am meeting Doctor next week and share the outcomes.
Avatar universal
Hi Stef

I have not tried Vitamin A supplements as yet but will find out & start taking it as well, what should be the dose.

Doctor suggested me multi vitamin named : Lycopene,vitamin,methylcobalamin,folic acid,chromium & sodium soft gelatin capsules( Make Medoscha gold) he asked me to take for 2 months. I noticed this is quite useful i feel more energetic now , last 1 month i am taking 1 capsule daily. Whats your opinion ..
Avatar universal
you know my concern is that there is something not working like high calcium with vitamin d within ranges and at the same time high pth with high calcium

before starting all that vit d i would go with low dose daily like 2000iu and take all vitamins correlated with vit d pathways to see if this gets solved.magnesium, vit A, vit k2 all work together with vit d and if there are deficiencies of these vits increasing vit d may not be good

gcmaf is the vitamin d transporter to receptors and nagalase made by hbv blocks gcmaf...i d be curious to see what your nagalase is but this is a research test and too difficult to get this in asia
Avatar universal
Hi Stef
Hope you are doing good , it has been long time we haven't communicate. i have done some test in-between ,i will attach these along with the previous one.
Vitamin D,25 Hydroxy:

- On 9 Dec.2015 : 71.69 nmol/L.
- on 10/10/2015 : 44.6 ng/ml.
- on 8 Nov.2013 : Vitamin D , 25 - Hydroxy ,Serum ( CLIA ) 41.05 nmol/L.
- on 22 June 2014Vitd25oh :18.22 ng/ml.
- on 24/8/2014 : 51 ng/ml.
- on 8 Nov.2014 : 51.2 ng/ml.
- on 5 Feb.2015 : 157.55 nmol/L ( Sufficient range 75-250 nmol/L )
- on 7 march 2015 : 164.50 nmol/L (CLIA method) Range 75-250 sufficient)
- on 3 April 2015: 174.12 nmol/L ( CLIA method - Ref.renge 75-250 sufficient )
- on 1 May 2015 : 65.2 ng/ml
- On 13/6/2015: 41.1ng/ml
- On 8/8/2015: 26.01 ng/ml ( Insufficient range)

PTH ( Parathyroid Hormone) Intact, Serum :

- On 12 Dec.2015: 77.3 pg/ml.
- on 10/10/2015 : 89.5* H pg/ml.
- on 5 Feb.2015 : 73 pg/mL ( Ref.Interval 14 - 72 )
-on 7 March 2015: 86.60 pg/mL ( CLIA method Ref.range 14-72 )
-on 3 April 2015: 73.60 pg/mL.
- On 1 May 2015: 83.80 pg/mL.
-On 13/6/15: 63.45 pg/ml.
-On 8/8/2015: 95.40 pg/mL. ( HIGH)

S.Creatinine:

- On 12 Dec.2015 : 1.11mg/dl.
- On 10/10/2015 : 0.90 mg/dl.
-On  10 May 2015: S.creatinine : 1.4 mg/dl.
-On 13/6/2015: S.creatinine : 1.09 mg/dl (HIGH)
-On 8/8/2015: 1.00 mg/dL

L.F.T.-

-On 12 Dec.2015:
ALT : 39 IU/L. , Serum Alkaline Phosphatase :135 IU/L , GGT: 20 IU/L , S.Total Protein: 7.2g/dl. , S.Albumin: 4.2g/dl. , S.Globulin:3 g/dl., A\G:1.40.

- On 10/10/2015:

AST/SGOT: 29 IU/L.
ALT/SGPT : 43* H IU/L.
Serum Alkaline Phosphatase: 115* H IU/L.
GGT: 19 IU/L
A\G Ratio: 1.46* L

- 28 Jan.2014
SGOT / AST 48 U/L.
SGPT / ALT - 106 U/L.
ALK . Phosphatase - 139 U/L.

L.F.T.-
-  27/4/2014-
SGOT / AST 40 U/L.
SGPT / ALT  65 U/L.
Alkaline Phosphatase ( ALP ) 143 U/L.

L.F.T :
9 August 2014:

Serum billrubin total ( Jendrassik- Grof) 0.8 mg/dl ,
Serum Billrubin direct ( Jendrassik - Grof) 0.1 mg/dl,
Serum Billirubin Indirect 0.70 mg/dl ,
AST/SGOT ( kinetic-Henry) 10 IU/L  ,
ALT / SGPT ( kinetic-Henry) 26 IU/L ,
Serum Alkaline Phosphatase ( Kinetic) 110 IU/L ,
GGT 22 IU/L , S.total Protein ( Bluret) 7.3g/dl ,
S.Albumin 4.1 g/dL ,
S.Globulin 3.20g/dL ,
A\G Ratio 1.28.

L.F.T
- on 8 Nov.2014:
Serum Biluirubin indirect 0.50 mg/dl ,
AST/SGPT ( kinetic - Henry) 24 IU/L. ,
ALT/SGPT ( Kinetic Henry) 34 IU/L. ,
Serum Alkaline Phosphatase ( Kinetic) 136 * High  IU/L. ,
GGT 17 IU/L. ,
S.total protein 7.8 g/dl. ,
S.Albumin 4.1 g/dl. ,
S.Globulin 3.70*High g/dl ,
A\G Ratio 1.11* Low.

LFT: On 25Jan.2015:
SGOT/AST:  12.8IU/L ( Ref.range 0.0 -37.0)
SGPT/ALT : 24.7 IU/L ( Ref.range 0-41 )

LFT : On 20 Fe.2015:
ALT : 26 IU/L ( Ref.Range 10-40)
Serum Alkaline Phosphatase 112* High IU/L ( Ref.Range 32-92)
GGT : 21 IU/L ( Ref.Range 7- 64)

LFT On 13/6/2015:
ALT 32 IU/L.
AST 19 IU/L.
Serum Alkaline Phosphatase 104 IU/L ( HIGH)
A|G ratio 1.34 (LOW)
GGT 17 IU/L.

LFT on 8/8/2015:
AST: 22 U/L.
ALT: 30 U/L.
GGTP: 22 U/L.
Alkaline Phosphatase ( ALP): 143 U/L.
Phosphorus: 2.00 mg/dL.

HBV DNA Quantitative , Real time PCR : Plasma
- on 28 Jan.2014- 5156250 IU/mL.
- 1 May 2014:  - 33181 IU/mL.

- 9 August 2014: = 5.72x10^2 IU/ml.

- 8 Nov. 2014: 47.5 IU/ml.
- 20 Feb.2015 : 6.04 IU/mi.
- 13/6/2016: HBV DNA NOT DETECTED.

HBsAg Quantitative:


- On 12 Dec.2015: 6485 IU/ml.
- On 10/10/2015: 6858 IU/ml.

- on 28 Jan. 2014:  : 7767.68 IU/mL.

- on - 1 May 2014:  6812.40 IU/m

- 9 August 2014: 3585 IU/ml.

8-  Nov.2014: 4633 IU/ml

- 20 Feb.2015 : 5174 IU/ml.
- 13/6/2015: 5431 IU/ml

FibroScan:

- On 10/10/2015: 3.8 (E kpa) , CAP ( dB/m) 272.
On 26 Dec.2014 : 4.7.
On 9 August 2014 : 4.9.
on 13/6/2015: CAP ( dbm) Median 270 , IQR 21. , E(kpa) Median 3.5 , IQR 0.5 , IQR/med 14%

Todays I showed all report to Doctor , he advised to change TIRAVIR 300mg with Sebivo 600 mg , his idea to change the medicine is to control the creatinine level. I checked the web site the salt is almost same in both the medicine . please suggest as per your experience.
Looking forward your reply.
Thank you,





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