HBV DNA VIRAL LOAD INTERPRETATION PLSSS

[yolandagrace]

please ineed someone to interprete the ff.

HVB DNA viral load

result-- 7,291 IU/ml

Remarks
1) HBV DNA viral load ( Real time PCR) == ( 6-110,000,000 IU/ml) 35- 640,200,00 copies / ml

2) Specimen with less than 6 IU/ml ( 640,200,000 copies /ml) is above the defined range of the test

Please help me to interprete the result... thak you

[stef2011]

anticolesterol and anidiabetes drugs are active on hbv too so you can take drugs like simvastatin and similar or rostiglitazone (or similar name) if needed

avoid alcool fat foods and meat, these ones as little as possible

you should also check your liver with fibroscan yearly to check the liver damage (the only machine that can tell liver damage) so you are safe...blood tests and ultrasound are useless to see liver damage, i d avoid biopsies because your are probably inactive with no liver damage and monitor hbvdna, alt, US, firbroscan

[yolandagrace]

thanks for all your help.

I have seen my MD few days ago, my liver ultrasound is normal, my sgpt and sgot are all normal now.

so far my case is as follows.

liver ultrasond---- normal
repeat sgpt and sgot-- normal
HVB DNA----- result-- 7,291 IU/ml
HBsAg-- ---reactive

I am hypertensive also taking hypertensive drugs, please advice me all about. What should I abstain taking ( foods)

Thanks

[stef2011]

i made another mistake, i am writting too much lately...
these two drugs might even eradicate hbv if hbsag is <15000iu/ml:

these two drugs might even eradicate hbv if hbsag is <1500iu/ml, inactive hepatitis have usually hbsag between 0.1-4000iu/ml, inactive carriers usually <1500iu/ml, truly 100% inactive carriers with more than 10% probability of seroconversion per year <500iu/ml

[enolia]

Your sgpt (or ALT alanine aminotransferase liver enzymes)  80 is HIGH. ALT usually indicate liver condition. If you are a female, a normal value should be up 20, 30 if you are a male... This can be lowered down by an antiviral treatment but the decision to start these treatment should be discussed thouroughly with your Dr because the treatment do not "heal" and you need to keep taking them for good (most of the time). There is also a cost and age aspect as these are very expensive and some people just want to wait and see how things evolve. Some people would just monitor their liver through either yearly ultrasounds, fibroscan to monitor liver damage and blood works to monitor any viral loads increase and they start treating only when there is a liver damage. It is important to discuss with your Dr all the scenarios and consequences on your life.

[stef2011]

no hbv and hcv are silent killers they have no synthoms, actually in general the killing diseases have no synthoms until too late

so it is important to check very carefully the disease, it can be very very mild or very aggressive but you don t feel it at all, i reached cirrhosis without any sign or blood test showing it, only fibroscan did, so follow all required tests to monitor and fibroscan yearly and your risk is almost zero

hbvdna und likely to infect only by blood, hbvdna detec infectious by sex/blood, very high hbvdna in the millions might infect by saliva/body liquids too although very difficult

hbvdna in the millions is only when there is no immune response, immune tollerant phase, usually when infected at birth or very young

[yolandagrace]

thanks stef..does it mean I am infectious can spread to others base on my HBV DNA viral load count?? .. anyway.. i am physically fit does not manifest any sypmtoms.

[stef2011]

interferon or nitazoxanide might be good therapies to make hbeab pos and normal alt

i'd not conisder antivirals like tenofovir or entecavir unless you have severe liver damage like f3-f4cirrhosis because you are too young and because you might get inactive by hbeab antibody

i'd try ntz first since no sides and if not working by 24 weeks i'd consider interferon combo, these two drugs might even eradicate hbv if hbsag is <15000iu/ml

[yolandagrace]

here are the result- ( what does it mean)

HBsAg-- reactive

HBeAg - negative

HBeAB - negative

HVC- negative

sgpt-  80

sgot- normal range

[cajim]

You have HBV.  Other test results?  ALT AST HBeAg HBeAB etc?