HBV Mutation

[scaredman2010]

I am a HBV carrier and has been on lamivudine treatment.
Recently, my LFT indicated a ALT(114), AST(207), ALP and GGT in normal range.
Is this because my HBV virus mutated?
Am very worry now.

[stef2011]

hbv has been isolated a long time ago so we can be certain about what the tests detect

if you dont isolate the tests can detect whatever, even our own cells

[stef2011]

no hbvdna is a goldstandard test, hiv rna detects who knows what, hiv has never been isolated
the indications of the producers of hiv tests say "this cant be used to determine an hiv infection"

look what nobels and biologists have to say about this fraud....do not waste your time on hiv, documentary "the house of numbers"
http://www.youtube.com/results?search_query=house+of+numbers&aq=f

[scaredman2010]

is the test of hbvdna the same that can detect hiv dna/rna as well?

[stef2011]

also hiv transmission is to be proved, many couples with one partner hiv pos had unprotected sex for years without any transmission, so it is very difficult to trasmit

it could have been mononucleosis but again even if you got 3 other hepatitis viruses you are still in great danger due to lamivudine, you were safer if you never started it.people without lam mutations are extremely rare

[stef2011]

not hiv, that has not even been scientifically proved to cause any disease or aids, it is probably just a cofactor.

the only thing for certain is that lamivudine doesn t work and that the longer you take it the more mutants you get

[scaredman2010]

could this be caused by caught another virus - HIV? I had an incident about one year before, that I had sex with a CSW. It is protected, but who knows.

[stef2011]

look all the other posts liver cancer and cirrhosis are not detectable by simptoms, you are fully normal right before you dye!

lamivudine can t be used anyway, even if you have hbvdna und and norma alt you cant use it, it doesn t owrk it will only worsen hbv.
it keep mutating even if hbvdna is und

alt at 40 is not normal, normal is below 30 and optimal is below 21

check hbvdna with high sensitivity at 6iu/ml or at least 20iu/ml, make resistance mutations test and add tenofovir as soon as possible

[scaredman2010]

The thing is I am all normal.
My ALT four days ago is 42 in the normal range. I hope the result above is only one abnormal...

[stef2011]

i see you are in china....do not start adeforvir or entecavir these are both useless, if you dont have early access to tenofovir start interferon or move to india for all the drugs i suggested

china has both resistance test (not full genome) which is enough and hbsag quant in iu/ml, move very fast because you are in very bad situation and also might end in death in worst situation

[stef2011]

of course it is, didn t you know lamivudine worsen hbv?

now you can use only tenofovir and you need to start it as soon as possible because if the mutants get hbvdna too high even tenofovir might not work

the flares are also very dangerous because they can end up in liver failure and death, if your country allows this i d sue the doctor since lam is out of hbv guidelines

i also suggest to add alinia (nitazoxanide), generic is nizonide500 and possibly interferon

if you can get to rome there is policlinico tor gvergata with full hbv genome test so you can see all the mutants done by lamivudine