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HBV Viral load decreasing without medications

I am hepatitis B chronic patient and I know for 15 years but could me more than that.
1- My viral load decreases.
a) Jan,2020 was 53 IU/ML.
b) June,2020was 38 IU/ML
c) Dec,2020 was <20 IU/ML

Hbsag Elisa shows 97.5 and then 78.5

2-All this time the ALT and AST level was normal.
3- Alpha Feto protein was 9 then 15 and now 12. This is down from 15 to 12.
3-MRE shows MILD Liver fibrosis.

I feel dull pain under the right rib cage which goes when I take antibiotics.
I AM NOT on medications.
Based on this information, please advise on my condition.
4 Responses
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Avatar universal
Sorry forgot to add.
Hbeag is negative.
MRE fibrosis is 5.7kpa
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Please help
Avatar universal
This is very good news. Are you doing anything different recently in diet?

Your virus load is decreasing which is extremely good. If this continues to happen you may clear the virus.
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Avatar universal
@Quincyw33. Thank you so much. No. I have not changed my lifestyle. I maintain the same pattern of lifestyle from the day I started doing tests. I was diagnosed 15 years ago but started doing tests 3 years ago.
My concern was despite decreasing HBV DNA, the
1-  HBSAG quantitative is >1000
2- HBSAG Elisa decreases from 97.5 to 78.
Which is which? What is difference between HBSAG quantitative and HBSAG Elisa?.  Once I know this then I can know the status and also help others understand better giving my case as a study.
Helpful - 0
the hbsag number followed by iu/ml (negative less than 0.05iu/ml) is the right test
Avatar universal
hbsag is not quantitative, the number means nothing wihout a unit.hbvdna goes up and down but means nothing too.you have to check hbsag quantitative in iu/ml to know if you are clearing something
Helpful - 0
If the HBSAG test says 'Quantitative Monitor/ QN Monitor' then it is the right test and it is reported in IU/ML. Elisa is simply the name of the method used to measure the levels.

The test that is the right test would sometimes say "Not for diag" and this means that is is only for people who already know they have the virus and want to monitor.

The other test that only shows whether you have it or not would say "for diagnosis" and this is usually not useful as stef2011 is saying because it only tells you if you have the virus. They usually report it like >0.01 or something like that.

When you get tests done at different places sometimes the results are slightly different and sometimes the report shows different units of measurements so read then carefully.

In the above comment you mentioned that 1-  HBSAG quantitative is >1000.  Was this the way that is was printed on the report or was it an actual number like 1256? This is important because for the diagnostic tests that they use to determine if you have the infection, they just check if it's above a certain point. So they don't care about the actual number. They just show that it's above a certain range. If they are not reporting the actual number then stef2011 is right and it is just the diagnostic test and it only tells you if you have the virus.

However, the second test you mentioned 2- HBSAG Elisa decreases from 97.5 to 78. This test I believe is the correct test and is the quantitative test and shows that the surface antigen level is going down. So you are doing really good!

When I started to take vitamin D my HBSAG started going down. It would not hurt to add 2000 IU of vitamin D a day.

I hope the numbers continue to go down. Thank God for your progress.
Is there away that I can attach the report here for a better perusal?.
I don't think you can attach things like that.
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