HBsAg Reactive

[ali256]

Sir for a job medical in 2005 i found incidently that

HBsAg +  ,   LFTs normal ,  HBeAg  Negative and HBe antibody positive

i had no problems with my health and still i am fit but now again in 2011 for another job medical my labs are as under

HBsAg Positive ,  HBs Ab Negative , HBc Ab Positive , HBeAg Negative ,  HBe Ab Positive , LFTs Normal and
PCR for HBV DNA ( Quantitative ) Negative

Now this HBsAg positive status is becoming a problem for my job abroad ,  how can i get it negative .. i am ready to take any medicines .. how about getting vaccine... interferon ... just want to get rid of this HBsAg please help me please

[wishful01]

what happened?

[ali256]

a lot of weakness

[Magda123]

Hi ali! What sides are you experiencing while on int?

[ali256]

yea must think positive to cope up side effects of pegasys

[StephenCastlecrag]

I am hoping it is an indication that your immune system is clearing the virus. Stef2011 will be able to tell you more. Keeping my fingers crossed for you.

[ali256]

Newtr kindly comment on my raised ALT

[ali256]

hey stephen also comment on my raised ALT

[ali256]

hey
got the 5th inj pegasys 180 mic today
platelet 159000
WBC 3000
ALT 103

ALT had always been normal before that  
HBsAg quantitative 20.9 iu/ml before starting therapy
Also taking Vit D

What does that mean

[ali256]

got two inj
many still to go
its tough but managable

[stef2011]

if you have reached good blood levels of vit d like 40-60ng/ml you can go on with pegintf and see hbsag at 24 weeks

[ali256]

stef ???

[ali256]

anything else i can do

[ali256]

thanks a lot
i was waiting for your reply since the time i had inj pegasys 3 days ago
first day was awful and now feeling almost normal

[ali256]

yes the unit is iu/ml
is that the right strategy
what do u think

[stef2011]

20.23, and the unit is iu/ml?

hbsag should go und by 24 weeks, add hbv vaccine when hbsag goes und

[ali256]

hbsag + since 2005
anti hbs -
hbeag -
anti hbe +
alt and ast normal
hbv dna less than 116 copies / ml ( undetectable )

HBsAg quantitaive from 19 to 13.4 then 16 and now 20.23 over last one year
No treatment taken

Now have started with
-PEG interferon 180 mcg once weekly
-Alinia 2gm daily in divided doses
-Vit D
-Simvastatin 20 mg daily

tolerated the first inj well
and continuing with the rest of meds

[newtr]

but check hbsag and cbc and report, it will be useful to predict future response.

[ali256]

yea its not that expensive
is it expected to come down so early
can be discouraging

[newtr]

test hbsag after 4 weeks instead of 8 weeks, its not too costly.

[ali256]

hbsag + since 2005
anti hbs -
hbeag -
anti hbe +
alt and ast normal
hbv dna less than 116 copies / ml ( undetectable )

HBsAg quantitaive from 19 to 13.4 then 16 and now 20.23 over last one year
No treatment taken

Now have started with
-PEG interferon 180 mcg once weekly
-Alinia 2gm daily in divided doses
-Vit D
-Simvastatin 20 mg daily
Today was the first day
will recheck HBsAg after 8 weeks

any suggestion ?
any hopes ?

[ali256]

Going to repeat the HBsAg quantitative
Did not take any medicines
18 months ago was 19
an year ago was 13.4
6 months ago 16

Fingers crossed lets see whats the result now

[misbah77]

Dear,

Please let me know that, in specifically my case where Hbsag value is 4007, which i have tested in June 2012 and DNA was not scanned in test. could i get success in medical examination for Australia immigration, as they have even mentioned on their website that they does not treat HBV as treat to public but in some cases need undertaking.
Please provide your doctrine in this regards, since i have received my EOI(Expression of Interest)  and have a chance of one month for visa application, but i need to pay a visa fees in this regards, which is approx 3060 AUS $ and i don't want to loos it.

Please advice.......
  

[Magda123]

Any update ali? Did you start with peginterferon?

[imran4535]

With numbers as low as yours I would do the following.

1. Start with a full set of labs and tests from a very good doctor
2. Get a genotype test and under an expert doctor look to start interferon therapy, possibly with Alinia

You may have a very good chance of clearing the virus if you act quick and smart. The virus is very smart, if you waste time it might get out of control of your immune system.

Also keep in mind in Pakistan most doctors are terrible. Your results could even be wrong.