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Hep B test inconclusive and confusing~!
My rheumatologist's office called and wants me to have bloodwork called Hep B Core AB IGM Total I dont know what this is but my test came back inconcluive so the nurse could only tell me that this test will give more info. Of course my dr was gone for the day.
I've had 3 sets of tests for Hep B. The Hep B Cab always comes back as REACTIVE This test was done a month ago. HepB sag non reactive. **Hep B AB Quant was 20.94 HIGH Range should be 0-9
In 2013, the same at when I had it done at a hematology center. Hep B Core Ab was Reactive Heb B Surf AB was 37.8 which stated is patient is considered to be immune to infec with HBV. Not determined what clinical significance if for values greater than 12. Other than immunity to HBV infection.
MY Cleveland Clinic results in 2013 was Hep B Core AB positive and also Hep B Surf AB Qual was Positive but both Hep C and HBsag were negative.
MY rheumy's nurse said my tests came back inconclusive and wants me to have the HepB core AB IGM Total done...
can someone explain this to me that knows something about Hep and values? NO one has mentioned anything about these tests to me since y first one in 2013.
also what does the IGM tell my dr and what could the results mean to me? more testing, vaccine?
I was dxd with cirrhosis in 2012. I see the hep at Cleveland Clinic every 6 months, US, labs, etc. Things have been good so far with pretty normal labwork in October.
Thanks to anyone who can answer this for me. So confusing!
Paula
I have had autoimmune disease rheum arthritis since 1984. also have sjogrens, raynauds, limited scleroderma...etc etc
I've had 3 sets of tests for Hep B. The Hep B Cab always comes back as REACTIVE This test was done a month ago. HepB sag non reactive. **Hep B AB Quant was 20.94 HIGH Range should be 0-9
In 2013, the same at when I had it done at a hematology center. Hep B Core Ab was Reactive Heb B Surf AB was 37.8 which stated is patient is considered to be immune to infec with HBV. Not determined what clinical significance if for values greater than 12. Other than immunity to HBV infection.
MY Cleveland Clinic results in 2013 was Hep B Core AB positive and also Hep B Surf AB Qual was Positive but both Hep C and HBsag were negative.
MY rheumy's nurse said my tests came back inconclusive and wants me to have the HepB core AB IGM Total done...
can someone explain this to me that knows something about Hep and values? NO one has mentioned anything about these tests to me since y first one in 2013.
also what does the IGM tell my dr and what could the results mean to me? more testing, vaccine?
I was dxd with cirrhosis in 2012. I see the hep at Cleveland Clinic every 6 months, US, labs, etc. Things have been good so far with pretty normal labwork in October.
Thanks to anyone who can answer this for me. So confusing!
Paula
I have had autoimmune disease rheum arthritis since 1984. also have sjogrens, raynauds, limited scleroderma...etc etc
Best Answer
Hi ann
Can i ask what your final results were after you got inconclusive reaults? My GP said i had hep b ag inconclusive and have to repeat test. Its takes 1 week for results and i am scared.
Thanks
Can i ask what your final results were after you got inconclusive reaults? My GP said i had hep b ag inconclusive and have to repeat test. Its takes 1 week for results and i am scared.
Thanks
vit d dose depends on your blood levels of vitd25oh and intact parathormone levels.ther exsist no fix dose, anyone is different and especially us with illnesses
the target is 60-90ng/ml for vitd25oh, 10-20pg/ml for intact pth (vitd25oh lowers pth) and vit k2 that you can get from japanese natto or from supplements like this:
https://www.bigvits.co.uk/product.asp?pid=953&cid=309&tid=&bid=
this is a good and cheap vit d, chose 5000 or 10.000iu pills, both are ok to start but then after 1 month you need to check vitd25oh, intact pth, calcium to know where you going
https://www.bigvits.co.uk/product.asp?pid=260&cid=240&tid=&bid=
as to source of calcium try to get it from vegetables sources instead of milk, some studies indicate milk worsen osetoporosis but anyway when vitd25oh is 60-90ng/ml you ll get enough calcium from all foods
the target is 60-90ng/ml for vitd25oh, 10-20pg/ml for intact pth (vitd25oh lowers pth) and vit k2 that you can get from japanese natto or from supplements like this:
https://www.bigvits.co.uk/product.asp?pid=953&cid=309&tid=&bid=
this is a good and cheap vit d, chose 5000 or 10.000iu pills, both are ok to start but then after 1 month you need to check vitd25oh, intact pth, calcium to know where you going
https://www.bigvits.co.uk/product.asp?pid=260&cid=240&tid=&bid=
as to source of calcium try to get it from vegetables sources instead of milk, some studies indicate milk worsen osetoporosis but anyway when vitd25oh is 60-90ng/ml you ll get enough calcium from all foods
search all the forum and vitamindwiki for info about your illnesses and liver.US is not a great place for healthcare, you have to look for the best ones in the country and study all posts here and of course studies correlated
liver damage, liver disease. low vit d, low vit k, high intact parathormone are all linked
fibroscan will tell how your liver is (not surprised in US you had no fibroscan and dont know about it).this i the only machine to tell you how your liver is and how it improves (no blood tests or US can tell you this)
just follow my steps from 2010 to 2013, i went from advanced micronodular cirrhosis (supposed to be so advanced not to regress) and it did in 1.5years from 16.3kpa to 6.3kpa, today i am in the 4kpa range)
you have to study all you can find here because most liver specialists are ignorant, so by studying here you will help yourself and will be able to understand if your doctor is good and updated
liver damage, liver disease. low vit d, low vit k, high intact parathormone are all linked
fibroscan will tell how your liver is (not surprised in US you had no fibroscan and dont know about it).this i the only machine to tell you how your liver is and how it improves (no blood tests or US can tell you this)
just follow my steps from 2010 to 2013, i went from advanced micronodular cirrhosis (supposed to be so advanced not to regress) and it did in 1.5years from 16.3kpa to 6.3kpa, today i am in the 4kpa range)
you have to study all you can find here because most liver specialists are ignorant, so by studying here you will help yourself and will be able to understand if your doctor is good and updated
Thank you for that link. I had a vitamin d bloodtest done and I am low....also have osteoporosis but now taking reclast infusions and its helping some. I am taking some vit d but not religiously. I always worry about what meds I take now.
Dr hasnt suggested a fibroscan. what is hbvdna? Is that found in the fibroscan?
My hep tells me that by the time I will need a transplant, I will be too old to have one. I am 65 now and they stop giving liver transplants in the 70's. Thanks doc. I imagine my other comorbidities doesnt help me much.
I just learned about bios maybe reactivating hep. I have been on so many of them..enbrel, humira for a short short time and lastly orencia. But I didnt think they were helping my lungs either though drs in england say rituxan may help r/a lung. I dont even know what other damage its caused me but wanted to stop them. My hands and feet are deformed..hands clawlike and so cant imagine what its going inside..or can I? My BMI is about 21, 22. I dont know what food changes to make because of my GI tract..IBD, etc. did I say I was a mess? I'm kind of sticking to cereals, eggs, salad, cukes. Ice cream..sure thats not good. But things that dont bother my tract.
I dont even know how much Vit D I need. I used to take Livatone but its expensive..so now silymarin.
I am on 5 mg prednisone, inderal, pepcid 30 mg. stopped the orencia..
Thank you for that link..will check it out now..
Dr hasnt suggested a fibroscan. what is hbvdna? Is that found in the fibroscan?
My hep tells me that by the time I will need a transplant, I will be too old to have one. I am 65 now and they stop giving liver transplants in the 70's. Thanks doc. I imagine my other comorbidities doesnt help me much.
I just learned about bios maybe reactivating hep. I have been on so many of them..enbrel, humira for a short short time and lastly orencia. But I didnt think they were helping my lungs either though drs in england say rituxan may help r/a lung. I dont even know what other damage its caused me but wanted to stop them. My hands and feet are deformed..hands clawlike and so cant imagine what its going inside..or can I? My BMI is about 21, 22. I dont know what food changes to make because of my GI tract..IBD, etc. did I say I was a mess? I'm kind of sticking to cereals, eggs, salad, cukes. Ice cream..sure thats not good. But things that dont bother my tract.
I dont even know how much Vit D I need. I used to take Livatone but its expensive..so now silymarin.
I am on 5 mg prednisone, inderal, pepcid 30 mg. stopped the orencia..
Thank you for that link..will check it out now..
I dont know...the hep doesnt know. I took mtx for a long long time and that is one med that is very toxic to the liver. When my liver enzymes went up 3 fold on mtx, I never had another drink. It never bothered me to stop. I used to work as a surgical secretary and worked in a clinical lab as a receptionist. I did come in contact with needles but we never thought of anything to worry about back then. This was back in the late 60's and in 1970's. I never did drugs. My alk phos is fine. I thought I may have autoimmune hep but those tests were good also. Hep isnt doing a liver bx. My platelets run 115-130. Hep thought maybe PBC but the bloodwork doesnt show that. I have r/a and all the overlapping diseases...and some rheum lung... I'm a mess.
check all vitamin d studies on both cirrhosis, liver damage and rheumatoid arthritis on vitamindwiki.com
if you have cirrhosis you are sure deficient on vit d and levels of it correlates with severity of cirrhosis, risk of liver cancer and death so you better corrrect it as soon as possible
check also how we regressed cirrrhosis, me included and how to monitor improvment by fibroscan.supplements and diet/lifestyle changes to regress that fast are posted and being hbsag neg and hbvdna neg will make regression faster
a bmi less than 25 and no processed fods with chemicals are mandatory, then correction of oxidative stress and deficiencies like vit d are mandatory too
try changes of diet, life style and supplements first and go for most toxic drugs only if everything fails and you risk a lot.being cirrhotic (hbv and liver cancer are in the liver waiting a door to come out) it is a little mad to think about immune suppressive therapies, you did it right to think twice because antiviral is not sure to prevent hbsag to come back positive and liver cancer
if you have cirrhosis you are sure deficient on vit d and levels of it correlates with severity of cirrhosis, risk of liver cancer and death so you better corrrect it as soon as possible
check also how we regressed cirrrhosis, me included and how to monitor improvment by fibroscan.supplements and diet/lifestyle changes to regress that fast are posted and being hbsag neg and hbvdna neg will make regression faster
a bmi less than 25 and no processed fods with chemicals are mandatory, then correction of oxidative stress and deficiencies like vit d are mandatory too
try changes of diet, life style and supplements first and go for most toxic drugs only if everything fails and you risk a lot.being cirrhotic (hbv and liver cancer are in the liver waiting a door to come out) it is a little mad to think about immune suppressive therapies, you did it right to think twice because antiviral is not sure to prevent hbsag to come back positive and liver cancer
Not really, you have recovered from a previous Hepatitis B infection and have developed immunity against Hepatitis B (your HBsAb is greater than 10 IU/L).
What do you think causes your cirrhosis?
What do you think causes your cirrhosis?
Thank you. I had no clue I had Hep B in the past. I dont even know how I would have gotten it actually.
I told my rheumy that I wanted off of the biologics because of the drug pamphlets and all the side effects, warnings, etc. I had just found out that a biologic can reactivate hep once you had it. I have cirrhosis now and know I can develop liver cancer. The nurse at Cleveland Clinic ordered a viral load test for hep b, surf antigen and hepatic function (had that before) in case I go back to a biologic..which I highly doubt. My rheumy ordered the IMG since one of my tests was inconclusive. the two remarks on my bloodwork results was that "results were obtained with the centaur xp. values ontained w/diff mfrs assay methods cannot be used interchangeably." these the nonreactive HBsag and the reactive HBcab.
also what is the hep b ab quant (high at 20.94 and values s/b 0- 9.99
Am I contagious at all since I had Hep B at one time? I am worried about being around my daughter and family.
I told my rheumy that I wanted off of the biologics because of the drug pamphlets and all the side effects, warnings, etc. I had just found out that a biologic can reactivate hep once you had it. I have cirrhosis now and know I can develop liver cancer. The nurse at Cleveland Clinic ordered a viral load test for hep b, surf antigen and hepatic function (had that before) in case I go back to a biologic..which I highly doubt. My rheumy ordered the IMG since one of my tests was inconclusive. the two remarks on my bloodwork results was that "results were obtained with the centaur xp. values ontained w/diff mfrs assay methods cannot be used interchangeably." these the nonreactive HBsag and the reactive HBcab.
also what is the hep b ab quant (high at 20.94 and values s/b 0- 9.99
Am I contagious at all since I had Hep B at one time? I am worried about being around my daughter and family.
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"“The present authors and the American Association for the Study of Liver Disease strongly recommend that all patients undergoing chemotherapy, immunosuppressive therapy, HSCT, or solid organ transplantation be screened for active or prior HBV infection by testing for HBsAg and anti-HBc in serum. … In addition, it is recommended that screening of patients with inflammatory bowel disease or other benign medical conditions necessitating long-term immunosuppressive therapy for hepatitis B be incorporated into their routine care,” they wrote. “While further study will be necessary to completely define the risks, benefits, and costs of universal screening, we feel that the evidence as it stands now is sufficiently compelling to make routine screening for hepatitis B a standard practice.”
http://www.healio.com/hepatology/chronic-hepatitis/news/online/%7B1d9c272b-ff9f-4af6-91fa-92943c4c4c60%7D/routine-screening-for-hbv-should-be-standard-practice-experts-say