there are cases in hiv pos/aids patients with a lot of hbv mutants without hbcab and/or without hbsag too, that's due to many mutations of hbv with a very weak immune system
in any case variants are possible in hiv neg too, hbsag negative hbv is more common than hbcab negative
if you google hbcab negative hepatitis b you might find some articles
Thanks for that but I didn't quite understand. Is it possible for a patient to be HBsAg POSITIVE but Anti-HBc Total NEGATIVE?
hbcab igm is always negative on cronic hbv and if you mean hbcab igg negative it doens tmake a big difference because even if positive the titer is very low
what really matters on hbv infection is:
hbsag quant in iu/ml (i bet this is inversely correlated with nagalase enzyms)
hbvdna
all the rest is not very important since immune response is suppressed by hbsag and there are very low/undetectables antibodies anyway