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Is it safe to switch from ETV+TDF Combo to TAF 25 mg?

Hello my mother has been on etv+tdf combo for the last 4 years with -ve hbv dna and normal ALT,AST. Actually she is LAM resistant so will it be safe to switch to TAF as per my doctor's recommendation?
1 Responses
Avatar universal
i would not risk anything there are no studies on taf potency on resistant strains, if you get taf resistance there is no way to rescue her
3 Comments
But taf resistance has not been documented during the long trial period
how many years?
Yes you are right! Phase 3 trials for taf are no more older than 36 weeks.
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