Hi Sunny, a question, where are you from?
benign for most carriers with no treatment required, just have hbsag quant in iu/ml by elecsys or architect , hbvdna in iu/ml, fibroscan, all every year
ultrasound every 6months
hbv genotype once
when you post all tests we can tell you if treatment is necessary.if you want to cure it you have to start tenofovir irrespective on tests and add on pegintf when hbsag less than 1000iu/ml
stef, is it good idea to start antiviral even when one is in immune tolerant phase? I mean normal ALT. Is there any comparative study on the effect of antivirals for patients with immune tolerant and immune clearance phases?
is it good idea to start antiviral even when one is in immune tolerant phase?
So that means, he/she has to do ALT test first, no?
no to know if immune tollerant:
hbsag very high
hbvdna very high
fibroscan less than 6kpa (perfect healthy liver)
ast alt less than 30 men, 19 women
immun tollerant has no immune response so no damage.i bet you did not read all our posts.....hbv makes no damage but is even making liver cells healthier, it is our immune response to make liver damage.no immune response no damage
I m 35. Usg normal, fibroscan F0-F1,normal. Hbv dna 6100 iu ml. HbeAg antibody positive, hepB e antigen negative. Dont know my genotype unfortunatelly.
Shall i begin treatment??
no because you have no damage but if you want to clear hbv once and for all test your hbsag quant in iu/ml and then we see if peg directly or tdf and peg add on later
Thanx Stef. I will def mention hbsag quant on my next visit. When hbv dna is quite low what is the risk of hcc?
immune tollerant: no risk
inactive very low risk
hbvdna und and hbsag less than 1000iu/ml low risk
high hbsag and high hbvdna low risk
the risk is correlated to degree of immune response, genotype C has higher risk
high hbsag and high hbvdna low risk, low ast alt, simialr stage to immune tollerant low risk