I'm taking entecavir,1 mg dose daily, from the beginning of March this year.
Age 27, male
On the 6th month of entecavir treatment I have done a tetanos shot. The next day I started to experience tingling and numbness all over the body, tinnitus in my ear and dizziness.
- I have done brain MRI - all ok
- I have done electric nerve test - all ok
Blood test:
- HBs positive
- Hbe positive
- HBV DNA at the 6th month on Entecavir 1mg 23 000 copies per ml
Blood panel 26th September 2017
Eritrocite(Rbc)4.86mil/µL4.20 - 6.00
Hemoglobina(Hgb)15.30g/dL13.50 - 17.20 Hematocrit(Hct)44.40%39.50 - 50.50 - Volum eritrocitar mediu(Mcv)91.40fL80.00 - 99.00 Hemoglobina eritrocitara medie(Mch)31.50pg27.00 - 33.50 Concentratia medie Hb/eritr.(MCHC)34.50g/dl32.00 - 36.00 Latimea distributiei eritrocitare12.30%10.00 - 15.50 Leucocite(Wbc)5.69mii/µL4.00 - 10.50
Limfocite %39.60%20.00 - 44.00 Limfocite2.25mii/µL1.10 - 4.50 Monocite %6.00%2.00 - 9.50 - Monocite0.34mii/µL0.10 - 0.90 Neutrofile %53.20%42.00 - 77.00
Neutrofile3.03mii/µL1.50 - 7.70 Eozinofile%1.00%0.00 - 5.50 - Eozinofile0.06mii/µL0.00 - 0.50 Bazofile%0.30%0.00 - 1.50 - Bazofile0.02mii/µL0.00 - 0.20 Trombocite (Plt)201.00mii/µL150.00 - 450.00
Volum trombocitar mediu (Mpv)9.40fl6.00 - 13.00 Trombocitocrit (PCT)0.19%0.12 - 0.43
Total cholesterol 281 mg/DL normal range under 200 mg/DL
Serum creatinine 1.03mg/dl laboratory range 0.72 - 1.18
TGP (ALAT/ALT) 39.00U/L 0.00
- 50.00
TGO (ASAT/AST) 28.00U/L0.00 - 50.00
Vitamina D (25-OH Vit.D3)* Abbott, Metoda CMIA, ser59.60ng/ml
Fibroscan done in October 7,4 kpa F2 fibrosis
Vitamin B12 result 168.00 Pg/ml
Normal range:187.00 - 883.00 Pg/ml
a) Values > 400 pg/ml they exlcud B12 deficit
b) Values < 400 pg/ml test Holotranscobalaminei (vitamin B12 active)
Is there any connection between entecavir, low b12 and tetanos shot?
Could entecavir depleted b12 vitamin.
Thank you,