MY LATEST LAB RESULT WEEKS 23

[soa923]

Before I start treatment HBV DNA 7998 IU/ml Hbsag quantification 15978 IU/ml fibroscan 7.8 kpa body weight 82kg obesity , ultrasound shows liver size to be 13.2cm with mild fatty  ALT 7.9 u/l  .   After 23 weeks of pegylated interferon injection HBV DNA 267 IU/ml body weight 67kg (from 82kg) ultrasound show liver size to be 12.6cm with grade 3 FATTY LIVER ALT 17 u/ l . My question is what causes the liver to show grade 3 fatty liver and reduction in size from 13.2 cm to 12.6 cm . Am worried because of the grade 3 fatty liver . Should I stop the injection? Should I be worried about the ultrasound result ? Can the liver return to normal ?

[stef2011]

vitamin E 1000 IU dialy

be sure you choose the natural type and not the synthetic

[soa923]

Thanks again. How can I know that the treatment is working , will it show on ultrasound that the fat is reducing

[Aduiski]

I don't know what exactly caused your very heavy liver fattiness...

However, check these web sites:

http://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/basics/definition/con-20027761
Go trough all of the sections on this page (links to jump to next section are bellow the text, to the right side).
..especially this subsection:
http://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/basics/lifestyle-home-remedies/con-20027761

You can read it here as well:
http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/hepatology/nonalcoholic-fatty-liver-disease/

As you have both hep b and very significant liver fatty-ness this is becoming very very serious issue and you must act - meaning you must totally change your died and start with regular exercise.

[soa923]

Can I be eating fruits such as apple, pineapple, pawpaw , banana, water melon, orange and groundnut , beans , yam and boiled plantain , I really need your help  , am presently taking TOCOVID tablets, can I include vitamin E 1000 IU dialy

[soa923]

@Aduiski thanks , so does that mean that the reduction is a good thing? How soon can I get rid of the fat from the liver ? I will start the exercise today. Also am not overweight again my present weight is 67kg I was 83 kg before I start peg interferon injection and LDL 81,  it was 170 before . My doctor give me TOCOVID tablet to be taking once a day but my concern is why is the scan now showing grade 3 fatty liver ? I was expecting a better result from the scan because of reduction in weight and LDL . What could cause it not to improve ?

[Aduiski]

Of of the possible reason for your liver reduction is reduction in inflammation of your liver. An inflamed liver enlarges.

[Aduiski]

It is your diet and your overweight that were contributing your fatty liver. You have to change the diet as indicated and start regularly exercising. You should exercise on at least 5 days per week but preferably 6-7 days per week for 30-40 minutes at the very least. That exercise should not be just walking...but rather running or swimming..something that makes your breading faster.
Start slower first 2 weeks until your muscles adjust....

[soa923]

Thanks I really appreciate your advice my vit d3 was 20.7 ng before I start treatment . I just order for vitamin d3 5000 IU  to be taken dialy I HOPE I can reverse the liver back to normal . Please which other supplement or vitamins should I take again

[nicolefor]

To soa923 , what Stef2011  says  is very pertinent , ''sugar suppresses immune system and increases insulin resistance and so makes fatty liver, also carbohydrates make glucose spikes'' Take  note of it . Your fibroscan was 7.8 kpa. have you tested it again after the 23 weeks treatment ? If you don't change your diet , your fibroscan may increase .

[stef2011]

i said  with zero sugar because sugar suppresses immune system and increases insulin resistance and so makes fatty liver, also carbohydrates make glucose spikes

paleo diet boosts immune system and avoid sugars which suppress immune system and make insulin resistance.

diet is mainly carbohydrate, no wonder.....

no it is easy if you change diet totally it will go and anybody can see that on ultrasound

also vitd25oh must be around 90-100ng/ml and intact pth lowest of normal.low vit d makes fatty liver and fibrosis all by itslef with no need of food or hbv

[soa923]

@stef2011 what do you mean by paleo diet ? And do you mean peg interferon suppresses the immune system and increase insulin resistance . My present diet is mainly carbohydrate . I was obese before I start peg interferon please stef2011 I really need your help . My doc told me today that it is difficult to assess progress of fatty liver if the ultrasound is not done by the same person

[stef2011]

do not stop peg bt change diet to paleo diet, with zero sugar because it suppresses immune system and increase insulin resistance

change your diet as i answered on the other post, size of liver changes and is not a concern in your case, you dont have to look at size but fibrosis and as long as firboscan doesn t go in the 14-75kpa range you have nothing to worry about.
liver regenerate itself so even if you cut half of it it will regenerate