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More about Hep B labs
.... just wanted to run by my results from my labs my rheumy ordered and that Cleveland Clinic ordered in case I go back on a biologic.
My rheumy ran Hbsag Non reactive
Hbcab Reactive high
Hep B AB Quant high at 20.94 s/b 0.00 to 0.99 (these are from results end of January) He said he ordered two tests though I only saw one on the script. which was the IGM. So now he needs me to have the Hep B core ab total serum ql drawn. He only rcvd the IGM test back (no results posted as yet?) Hate when that happens. I have had rheum arth since 1984.
Cleveland Clinic ran the Hep B Viral DNA Quan which was Negative
Hep B Surf AG Screen which was Negative
Hep B Core ab total - Positive result rechecked
Hepatic Panel which was normal range mostly.
I will get labs drawn for Hep B Core AB Total Serum ql this week. Also have no knowledge of what the Igm showed
Can you give me an idea why? This is all Grrek to me so simple English would be appreciated.
Thank you....
Paula
My rheumy ran Hbsag Non reactive
Hbcab Reactive high
Hep B AB Quant high at 20.94 s/b 0.00 to 0.99 (these are from results end of January) He said he ordered two tests though I only saw one on the script. which was the IGM. So now he needs me to have the Hep B core ab total serum ql drawn. He only rcvd the IGM test back (no results posted as yet?) Hate when that happens. I have had rheum arth since 1984.
Cleveland Clinic ran the Hep B Viral DNA Quan which was Negative
Hep B Surf AG Screen which was Negative
Hep B Core ab total - Positive result rechecked
Hepatic Panel which was normal range mostly.
I will get labs drawn for Hep B Core AB Total Serum ql this week. Also have no knowledge of what the Igm showed
Can you give me an idea why? This is all Grrek to me so simple English would be appreciated.
Thank you....
Paula
500iu of d3 is nto existent, all studies on doses are wrong, the minimum is 10.000iu of d3 daily which is normally made by healthy people under intense sun
calcium must be avoided in supplements, once vit d rises you take it from food
vit k2 mk7 is also a must because it fixes calcium in the bones, deficiency let calcium accumulate on organs and vessels
magnesium is also a must
tests must be in ng/ml
there are a lot of frauds on vit d from drug makers because most modern diseases can be controlled by vit d and not drugs
on vitamindwiki.com u see all studies and will understand where the fraus is
vitd 46 is low on any unit and deficient on lmol/l unit, better refer only to ng/ml unit and optimal is 60-100ng ml.best 100ng/ml
again no calcium
calcium must be avoided in supplements, once vit d rises you take it from food
vit k2 mk7 is also a must because it fixes calcium in the bones, deficiency let calcium accumulate on organs and vessels
magnesium is also a must
tests must be in ng/ml
there are a lot of frauds on vit d from drug makers because most modern diseases can be controlled by vit d and not drugs
on vitamindwiki.com u see all studies and will understand where the fraus is
vitd 46 is low on any unit and deficient on lmol/l unit, better refer only to ng/ml unit and optimal is 60-100ng ml.best 100ng/ml
again no calcium
Oh I see...the antiviral. I will ask him when I see him for my appt in a month.
I have been off the biologic since early december and I really have not had pain at all. My pain was so bad in the early days 1983 till about the the mid 90s..when I started with the bios but now I dont have pain even off of it. I just checked my labs from December and my vit d registered at 46 s/b 24-80. I've been taking Calcium Citrate + D3 Vit D3 500 iu Calcium 400mg and sodium 5 mg (know the sodium is prob not a good idea). 1 daily.
Lots of questions for my rheumy, pulmonologist and hepatologist.
Enjoy your weekend.
Thank you stef
I have been off the biologic since early december and I really have not had pain at all. My pain was so bad in the early days 1983 till about the the mid 90s..when I started with the bios but now I dont have pain even off of it. I just checked my labs from December and my vit d registered at 46 s/b 24-80. I've been taking Calcium Citrate + D3 Vit D3 500 iu Calcium 400mg and sodium 5 mg (know the sodium is prob not a good idea). 1 daily.
Lots of questions for my rheumy, pulmonologist and hepatologist.
Enjoy your weekend.
Thank you stef
Hepatitis B Core AB Igm Ser QN
Hepatitis B Core AB Tot Ser QL
The above are the two tests my rheumy ordered at the end of January but somehow only the Igm was run and he had to order the AB Tot Ser which was either not run by the lab...or he didnt order it. why would he order these two tests? He hasnt seen the Cleveland Clinic bloodwork results. But he does have the others since he ordered them. Is this just to make sure all is fine if I do start on another immunosuppressant? which I wont.
I do take prednisone 5 mg..is that a better choice than the biologic? I know my esr increases without the biologics.
Hepatitis B Core AB Tot Ser QL
The above are the two tests my rheumy ordered at the end of January but somehow only the Igm was run and he had to order the AB Tot Ser which was either not run by the lab...or he didnt order it. why would he order these two tests? He hasnt seen the Cleveland Clinic bloodwork results. But he does have the others since he ordered them. Is this just to make sure all is fine if I do start on another immunosuppressant? which I wont.
I do take prednisone 5 mg..is that a better choice than the biologic? I know my esr increases without the biologics.
Thank you stef..my eyes are crossing.
I told the rheumy that I wanted to stop the biologics..immunosuppressants. I have been on humira, enbrel, orencia, mtx *bad*... and he didnt want me to. He wants me to use xeljanx but I said No, they dont seem to be helping me. The bios dont seem to be stopping the progression of the ra....matter of fact, I now have lung issues also. and all the overlapping r/a diseases. I am only on 5 mg prednisone now. But I know my inflammation is higher on lab results.
I was looking at the drug info and saw that these can reactivate hep and I was concerned. I asked him about it and then he ordered the hep tests and tb. I've been on them for 10 yrs or more!? I dont know if he knew that they can reactivate hep. I talked to my hepatologist who had ordered the tests when I was first dxd with cirrhosis in 2012 and knew I was still on them. I mentioned it to him when I went off and he said if I went back on bios, I'd have labs every 3 months. Shouldnt I have already had them done then? I will look up tenofovir. and add more vit d.
Thank you for your help...its wonderful to have members like you that can explain these things that are so difficult to understand. Have a great evening...
I told the rheumy that I wanted to stop the biologics..immunosuppressants. I have been on humira, enbrel, orencia, mtx *bad*... and he didnt want me to. He wants me to use xeljanx but I said No, they dont seem to be helping me. The bios dont seem to be stopping the progression of the ra....matter of fact, I now have lung issues also. and all the overlapping r/a diseases. I am only on 5 mg prednisone now. But I know my inflammation is higher on lab results.
I was looking at the drug info and saw that these can reactivate hep and I was concerned. I asked him about it and then he ordered the hep tests and tb. I've been on them for 10 yrs or more!? I dont know if he knew that they can reactivate hep. I talked to my hepatologist who had ordered the tests when I was first dxd with cirrhosis in 2012 and knew I was still on them. I mentioned it to him when I went off and he said if I went back on bios, I'd have labs every 3 months. Shouldnt I have already had them done then? I will look up tenofovir. and add more vit d.
Thank you for your help...its wonderful to have members like you that can explain these things that are so difficult to understand. Have a great evening...
now the only thing that you must be careful is drugs that suppress immune system, better never use them,they suppress b cell response and if there is even one template of hbv inside a cell (no virions at all, i mean a template of the virus) once the immune suppressive drug is used hbv infection can come back in a deadly way
unfortunately there is no way to know if any viral template is left after decades from clearance but the many cases of hbv coming back after chemio or immune suppressive drugs suggests that it happens
so be careful in the future and if a drug like a chemio, or steroids or rheumatoid drug is to be used, you simply take tenofovir antiviral before starting these drug and no hbv will com back as long as the antiviral is taken
unfortunately there is no way to know if any viral template is left after decades from clearance but the many cases of hbv coming back after chemio or immune suppressive drugs suggests that it happens
so be careful in the future and if a drug like a chemio, or steroids or rheumatoid drug is to be used, you simply take tenofovir antiviral before starting these drug and no hbv will com back as long as the antiviral is taken
Hep B AB Quant 20.94 mIU/m
this is hbsab, the immunity antibody for hbv, you had a past infection and now you are immune.this is 100% sure because the unit miu/ml is used only for the quantitative antibody against hbv surface antigen which makes a person immune
so nothing to discover or order more...sorry your doctor is so ignorant about hbv but we often find even liver specialists with no knowledge of the disease...this is dangerous for the patients
this is hbsab, the immunity antibody for hbv, you had a past infection and now you are immune.this is 100% sure because the unit miu/ml is used only for the quantitative antibody against hbv surface antigen which makes a person immune
so nothing to discover or order more...sorry your doctor is so ignorant about hbv but we often find even liver specialists with no knowledge of the disease...this is dangerous for the patients
This is from Cleveland Clinic..
HEP B SURFACE AG NEGATIVE
HEP B VIFAL DNA QUAN NEGATIVE NOT DETECTED linear range of assay is 20-170,000,000 iu/ml
HEP B CORE AB TOTAL IS POSITIVE rechecked.
I couldnt copy and paste their info.
Hepatic panel was pretty normal
HEP B SURFACE AG NEGATIVE
HEP B VIFAL DNA QUAN NEGATIVE NOT DETECTED linear range of assay is 20-170,000,000 iu/ml
HEP B CORE AB TOTAL IS POSITIVE rechecked.
I couldnt copy and paste their info.
Hepatic panel was pretty normal
These are the tests I am waiting for results and to get lab done He has the igm but not the core ser QL since he didn't order it or the lab didn't run it.
Hepatitis B Core Igm & Total 02/26/2015
Hepatitis B Core AB Igm Ser QN
Hepatitis B Core AB Tot Ser QL
RESULTS from 12/29 Rheumy:
Hepatitis C Antibody 12/29/2014 HCV AB NONREACTIVE Nonreactive 4
Laboratory test finding 12/29/2014 Hbsag NONREACTIVE Nonreactive 5
Hbcab Reactive High Nonreactive 6
Hep B AB Quant 20.94 mIU/mL High 0.00-9.99 7
4 SCREENING TEST NEGATIVE NONREACTIVE HCV ANTIBODY SCREEN IS CONSISTENT WITH NO HCV INFECTION, UNLESS
RECENT INFECTION IS SUSPECTED OR OTHER EVIDENCE EXISTS TO INDICATE HCV INFECTION
5 RESULTS WERE OBTAINED WITH THE CENTAUR XP. VALUES OBTAINED WITH DIFFERENT MANUFACTURERS' ASSAY
METHODS MAY NOT BE USED INTERCHANGEABLY.
6 RESULTS WERE OBTAINED WITH THE CENTAUR XP ANTI-HCB ASSAY. VALUES OBTAINED WITH DIFFERENT MANUFACTURERS'
ASSAY METHODS MAY NOT BE USED INTERCHANGEABLY.
7 STATUS OF IMMUNITY Protective Immunity: greater than or equal to 10 mIU/mL (Traceable to WHO International Reference Preparation)
No Protective Immuniity: less than 10 mIU/mL Note: The magnitude of the measured result above the cutoff is not indicative of the total
amount of antibody present.
will send CC next Thank you!
Hepatitis B Core Igm & Total 02/26/2015
Hepatitis B Core AB Igm Ser QN
Hepatitis B Core AB Tot Ser QL
RESULTS from 12/29 Rheumy:
Hepatitis C Antibody 12/29/2014 HCV AB NONREACTIVE Nonreactive 4
Laboratory test finding 12/29/2014 Hbsag NONREACTIVE Nonreactive 5
Hbcab Reactive High Nonreactive 6
Hep B AB Quant 20.94 mIU/mL High 0.00-9.99 7
4 SCREENING TEST NEGATIVE NONREACTIVE HCV ANTIBODY SCREEN IS CONSISTENT WITH NO HCV INFECTION, UNLESS
RECENT INFECTION IS SUSPECTED OR OTHER EVIDENCE EXISTS TO INDICATE HCV INFECTION
5 RESULTS WERE OBTAINED WITH THE CENTAUR XP. VALUES OBTAINED WITH DIFFERENT MANUFACTURERS' ASSAY
METHODS MAY NOT BE USED INTERCHANGEABLY.
6 RESULTS WERE OBTAINED WITH THE CENTAUR XP ANTI-HCB ASSAY. VALUES OBTAINED WITH DIFFERENT MANUFACTURERS'
ASSAY METHODS MAY NOT BE USED INTERCHANGEABLY.
7 STATUS OF IMMUNITY Protective Immunity: greater than or equal to 10 mIU/mL (Traceable to WHO International Reference Preparation)
No Protective Immuniity: less than 10 mIU/mL Note: The magnitude of the measured result above the cutoff is not indicative of the total
amount of antibody present.
will send CC next Thank you!
I DON'T see igm on that test but do see this listed as
Hep B AB Quant as high at 20.94 0.00-9.99
The rheumy wrote an order for the igm and also total but only rcvd igm test back so now I need to have the Hep B core AB total serum ql done. he hasnt posted the IGM yet on my portal.
I have had rheum arth for 33 yrs.
If hb sab is surface antigen that registers negative.
Hep B AB Quant as high at 20.94 0.00-9.99
The rheumy wrote an order for the igm and also total but only rcvd igm test back so now I need to have the Hep B core AB total serum ql done. he hasnt posted the IGM yet on my portal.
I have had rheum arth for 33 yrs.
If hb sab is surface antigen that registers negative.
my rheumy.....
also be aware that some rheum drugs are so immune suppressive that any past infection, even if clear decades ago, can come back in a deadly way.maybe this doctor is checking for any past hbv infection to use these drugs?
before using those drugs i d try vitamin d
http://www.vitamindwiki.com/Rheumatoid+Arthritis
other members came here about these drugs and it is best to correct vitd25oh and intact parathormone first and see if the diseases lessens this way.if you dont take vit d you are sure 99% deficient and no way optimal ranges to stop these diseases.the target is vitd25oh around 100ng/ml and at the same time intact pth 10-20pg/ml (lowest normal for the lab range)
also be aware that some rheum drugs are so immune suppressive that any past infection, even if clear decades ago, can come back in a deadly way.maybe this doctor is checking for any past hbv infection to use these drugs?
before using those drugs i d try vitamin d
http://www.vitamindwiki.com/Rheumatoid+Arthritis
other members came here about these drugs and it is best to correct vitd25oh and intact parathormone first and see if the diseases lessens this way.if you dont take vit d you are sure 99% deficient and no way optimal ranges to stop these diseases.the target is vitd25oh around 100ng/ml and at the same time intact pth 10-20pg/ml (lowest normal for the lab range)
anyway make sure to have hbsab and hcab igg and igm so you can understand everything
Hep B AB Quant high at 20.94
this is not a correct way to call a test, there are so many antibodies in hbv infection, can this be hbsab instead of hbcab igm?do you have the results with you and the name of the test, the range with the units, machine used for the test?
it is wrog to call a test hep B ab, but i d think more of hbsab than hcab
Hep B AB Quant high at 20.94
this is not a correct way to call a test, there are so many antibodies in hbv infection, can this be hbsab instead of hbcab igm?do you have the results with you and the name of the test, the range with the units, machine used for the test?
it is wrog to call a test hep B ab, but i d think more of hbsab than hcab
Hep B AB Quant high at 20.94
so this is hbcab igm and it is detected?if igm is detected this is a recent infection and if hbsag is negative and hbsab not detected you are on time for hbv immune globulin and hbv vaccine, but this must be made in a clear set of markers and very fast, i mean these stupid cheap tests are ready same day in good labs and if you have all the clear picture you go for immune globulin.also a recent exposure like healthcare settings such as dentist or similar where the infection can be spread
what about hbsab?which is the main immunity antibody, most western countries have these by hbv vaccine and population is covered from hbv
so this is hbcab igm and it is detected?if igm is detected this is a recent infection and if hbsag is negative and hbsab not detected you are on time for hbv immune globulin and hbv vaccine, but this must be made in a clear set of markers and very fast, i mean these stupid cheap tests are ready same day in good labs and if you have all the clear picture you go for immune globulin.also a recent exposure like healthcare settings such as dentist or similar where the infection can be spread
what about hbsab?which is the main immunity antibody, most western countries have these by hbv vaccine and population is covered from hbv
There was only 1 lab ordered on the script my rheumy faxed. Not two..unless it was written as one test. IGM total? What do I know?
I felt this so confusing anyway but you're right MESSY! Wednesday I go for the draw for Hep B core ab total serum ql....maybe he is adding this because of the igm values.
Frustrating when other labs are thrown into the mix. I'm losing hair at a fast pace.
Thank you stef.....P
I felt this so confusing anyway but you're right MESSY! Wednesday I go for the draw for Hep B core ab total serum ql....maybe he is adding this because of the igm values.
Frustrating when other labs are thrown into the mix. I'm losing hair at a fast pace.
Thank you stef.....P
tests ordered in a messy way when everything is so easy (hbvdna pcr was a robbery, first you check if there is hbv then you check pcr which is the most expensive and no needed because the 4 cheap markers clear evrything):
hbsag
hbsab
hbcab igg and igm
from these you have complete picture...., hbcab should never be ordered total but igg and igm so you have more details (maybe a mistake of the lab to make total)
hbsab will confirm total immunity on hbv and no need to check hbcab igm if this is over 10miu/ml
hbsag
hbsab
hbcab igg and igm
from these you have complete picture...., hbcab should never be ordered total but igg and igm so you have more details (maybe a mistake of the lab to make total)
hbsab will confirm total immunity on hbv and no need to check hbcab igm if this is over 10miu/ml
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also do follow my suggestion to make vitd25oh 100ng/ml, if vit d receptors are working intact parathormone should fall in the lowest range of normal which is 10-20pg/ml for most labs.the minimum dose to do this is 10.000iu of vit d3 daily.this may lessen all reumy pains and help liver and kidneys repair themselves or at least work better
try the vit d3 first before going for heavy drugs.i am not on expert on remy drugs so i prefer not to suggest anything where i am not expert on toxicity/immune system balance