NASVAC is meant to be a therapeutic vaccine, so the results of the Phase II trials are keenly awaited as they should be testing on patients with chronic hepatitis B. A paper was presented at a recent conference in Cuba by the doctor in charge of the Bangladesh trial. The Cuban press hailed the vaccine. Despite numerous requests to the Conference organizer about publishing papers from the conference, no reply was ever received. A direct request to the doctor concerned elicited only the most general response. So, we still have no concrete figures about the results from any of these phase II/III trials. I hope you would have better luck.
That´s what they say, the phase II/III is ending... If I understood well it is very promising..
That is what they keep on saying, without publishing any data - very frustrating.
...then of course all the producers of antivirals and interferon will be ungry because for them is much more lucrative keeping us sick...
Just to clarify some things.can we say that the hbv theraupetic vaccines will increase the odds of becoming hbsag -ve.they will be used(if proven effective)mono or in combination with existing hbv therapies?do they act on hbvdna or on hbsag?thanks in advance.
If I have read well, there was 100% seroconverted people in trial..
this info was disclosed along with other information ?
I have asked the info directly via e-mail the Cuban institute, so they have sent me two huge PDF files..
Is it possible to send us a copy of the PDF files if I give you my email address?
of course, but I am not sure you can put your e-mail address here..
send me an e-mail to david.***@**** then I will send you those files back
you see, I tried to put my e-mail and it deleted part of it..:-(
you can use space:
name @ yahoo . com
or you can put the files on google docs and put the link, so everybody can see the docuemnts
Thanks, my email address is
swong888 at gmail.com
if is possible I want to see this results also
st4est at gmail.com
I have sent it, just tell me if when zou dont get it.
Many thanks for the files. It is greatly appreciated.
hello david, could you also send it to me please?
pkmedinfo A gmail.com
could you send one to me too? thank you
Stephen & David i suppose you have read the article. Can you please inform us briefly about the results of nasvac(% hbsag loss, % hbvdna undetectable) when it will be available? thank you in advance.
Sounds like a very good news.
I tried to google this too but I didn't find any answer. Can anyone tell me how long will it roughly take for this Vaccine to be available for general use? that is ofcourse of everything goes according to plan. If phase ||| trails are coming to an end doesn't this mean it will be available soon e.g. in 1 or 2 years?
Thanks in advance.
DavidEurope had very kindly sent us the files. However, the files did not contain any results from the Phase 2 clinical trials of NASVAC. It had the results of a Phase I trial that demonstrated NSAVAC is safe in healthy volunteers and is able to induce immune response against HBV through the production of antibodies.
The effect of NASVAC on patients with chronic Hepatitis B is yet to be announced. The second file is a paper that explains the scientific basis for investigation of therapeutic vaccine.
According to media reports, the results of the ongoing Phase 2 trials are promising.
The clinical trial Phase II-III is ending. The vaccine is not registered yet for general use. Clinical trials are ongoing in Cuba and Bangladesh and new trials should start in Brazil and Europe next year.
I think it is very promising. Cuba got a huge power in the production of pharmaceutics. There were a lot of doctors comming to the Cuban hepatitis conference this year, that means it is something very important.
I dont understand too much all that HBV mechanism but would the vaccine heal us 100% ? Would it mean no more virus? Could I drink good French wine again? And now, when Entecavir will make the virus undetectable..can I drink a little again? I am already fed up of telling my friends that I cant have a drink with them...