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Potential Cures for HBV

There are two very recent articles concerning POTENTIAL cures for Hepatitis B:

1.http://www.medscape.com/viewarticle/829588_6

Strategies to Eliminate HBV Infection
What novel strategies are being used to achieve sustained cure or elimination
of HBV? View on www.medscape.com, registration may be required. Registration is free.

Rama Kapoor1,2 & Shyam Kottilil*,2

1Clinical Research
Directorate/Clinical Monitoring Research Program, Leidos Biomedical
Research Inc., (formerly SAIC-Frederick, Inc.) Frederick National
Laboratory for Cancer Research, Frederick, MD 21702, USA

2Laboratory of Immunoregulation, National Institute of
Allergy & Infectious Diseases, NIH, Department of Health & Human Services,
Bethesda, MD 20892, USA


2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069299/

Emerging antivirals for the treatment of hepatitis B
World J Gastroenterol. Jun 28, 2014; 20(24): 7707–7717. Published online
Jun 28, 2014. doi:  10.3748/wjg.v20.i24.7707 PMCID: PMC4069299 Emergi...

18 Responses
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Avatar universal
Yet they have no problems putting out a Hep C cure, right?

Has anyone considered taking these type of arguments to a bigger social media board? Places like reddit may gather more attention to this kind of stuff, and maybe even help this issue go viral.
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Avatar universal
3 of potential drugs, arc520, npv018 and ? Oh 1 drugs is on the earth right now ? Hahahahaha.... we bore to read the potential cure... like this topic
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Avatar universal
the decisions that they make sometimes can make one to feel that they don't need a cure, they mostly push for antivirals which will most likely not cure us, whiles the immune modulators are there to help us cure it.
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Avatar universal
You mean to tell me my doctor won't want to give me a  cure?

The guys down by the Billabong reckon that doctors always try their best to cure everyone of everything. I thought they would always get their salary...

But I thought they would have to take an oath to say they were good people?

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Avatar universal
I think because of a vaccine nobody is interested to invest in a cure release the right amount of money, to have a strong public awareness of HBV like there is about HepC, HIV and Cancer.

But even these diseases are being also manipulated. HIV can be cured with a bone marrow transplant. Cancer with immune therapies that are also in trials now.
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Avatar universal
I am not going to take that risk,because I don't have any issue on my liver(for now). YES, I will if I would have damage on liver, or my situation is getting worse. There are a lot of people that are on bad situation now, and ready to take advantages on new therapeutic technologies. These companies,would have to take advantages on sick people as well. This is the time for them to win money. When? 2 new decades generation is already vaccinated. I don't understand what are they awaiting, they want money,we want cure.
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Avatar universal
If Replicor is using it in their clinical trials then it must work as good as interferon. It is a synthetic Thymus pretty much.

Why no proof? I have no idea! Lets write to Scicore. They usually respond. Several years back their sales rep has told me point blank that with a nuc you will clear hbv in 8-12 month. I was not able neither of my hepatologists to give me a prescription to import it and try. I told them I am willing to pay and take all the risks. They told me NO. :(

It is the same thing with Alinia btw. It works but no official proof. Nobody is interested. Big Pharma is running the show with nucs.

These small companies like Romark Scicore and Replicor just should sponsor patients that are willing to fly.
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Avatar universal
So pathetically, produced in CA, and no used. I browse Zadaxin,and it is approved since 2001 in many countries,what about hepB? are there any results showing decrease of hbsag cause of using it/,logically it can be since is an immune simulator,but i mean real facts,patients?
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Avatar universal
This is very frustrating. Better treatments are there. And the choices for us are so limited.
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Avatar universal
Allah is our hope to expedite discovering hbv cure ..
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9624973 tn?1413016130
I think by now people should start to wake up and see that the cure is already here, they just move to slow maybe because like others said , they have no interest in coming on the market. People should start to wake up because no one will care for our health . For them its just BUSSINESS !!
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Avatar universal
this can be used with NUCS to avoid harsh side effects of interferon with the same results.
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Avatar universal
ZADAXIN directly targets virally infected or cancer cells by:
Increasing the number of surface-marker proteins (MHC Class 1) that are responsible for identification and rejection of foreign agents, like viruses, from the body.

Slowing down the replication of viruses.
Decreasing oxidative stress, which dramatically decreases viral replication.

And it is completely safe with NO sides, short or long term. basically it is a synthetic form of what thymus gland produces.
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Avatar universal
This is something to read on Zadaxin. Makes me ask why things are so bad with medicine when it helps with so many diseases.. Made in California but order through Panama via import! That folks is right there a proof how they care for our quality of life.

=================== a post from another forum...

I was interested in Zadaxin a while back. I contacted a Mr. Greg Olson of Pharmaceutical Solutions by email, and he responded very promptly. Toll free phone # 1-888-322-2244, or email at ***@****.

As I recall, Zadaxin is approved for sale in 33 countries. It is not yet approved in the US, but can be legally imported. I beleive that Mr. Olson is in Panama. The Zadaxin needs to stay refrigerated, so it has to be shipped overnight. I seem to remember that Pharmaceutical Solutions is in Panama, so shipping is quite expesive.

A year ago I was quoted the following: $ 205.00 per box of two vials. Also included is two vials of dilutant for injection prep. FEDEX shipping adds $ 150.00. An order of 12 boxes, the largest amount that can be brought into this country at one time, is $ 2,610.00. This would be a 3 month supply, so the monthly cost is $ 870.00 per month.

There are customs forms that Greg will send you to be filled out. You also need a perscription from a US doctor.

It is really a shame that this drug is manufactured in California, and yet has to be shipped to Panama first.

The cost is high enough that I would like to know it was going to work before I tried it.

John
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Avatar universal
There is no reason for Replicor that has a proven Hbsag knocker to still be in clinical trials. That is like now giving thirsty and dying people water. They know it works but yet don't release.

But we sit here and wait. We have to expose all this. They have to change the way drugs are released for deadly viruses and cancers. For us it is life and death literally.
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Avatar universal
CURE FOR HBV is HERE!!!

most of those agents they speak of have been out for a long time. Alinia and Zadaxin. Do you see them been used?

What we see in clinical trials more nucs, and more tenofovir variants. Instead of immune system therapies.
Helpful - 0
Avatar universal
If real world outcomes reflect your optimism, it would be great!
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Avatar universal
We all know the cure is on way, what we hoping is that this cure will come soon on market. Anyway, glad to hear good news,
Helpful - 0
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