Question on side effects

[Cjb3695]

So Ive been on Viread for 3 years now. Im still eagpositive(forgot the actual term). The virus is still active. But whats bothering me alot lately is my bones. I feel my bones thinning. I lost alot of body mass over the last year. Im also experiencing my bones cracking in places Ive never heard it crack in before and cracking on a constant every other minute basis. So I went and tested Vitamin D. Supposedly it was just under low. So now I'm taking Vitamin D 50,000 weekly. I think its cracking even more now(when I say crack its making pop noises when I move mainly in joints) Also the bones feel alot more fragile now. My question is have anyone else experienced this? And what are my options? Also is it normal to be eagpos 3 years in from taking viread?

Thanks ahead of time!

[mustthinkpositive]

Are you taking Vit D3, not the D2 or other version?

[Goldentree]

Appreciated, thanks Stef

[stef2011]

5000iu daily is a very low dose you can do whatever, also 10.000iu daily is a physiological dose

vit k2, no dairies diet and 2.5l of water daily are for those making serum levels 100-160ng/ml

also test pth if you go for higher vit d doses to make vitd25oh over 100ng/ml

as to milk it is the calcium and the antibiotics, drugs, low quality food animals are fed that are passed to us.if source of dairies is not knwon as organic and so on it is healthier not to have it in the diet

fat is beneficial to immune system

so t sum up, the bad of dairies is:
humans are not designed to drink cows or other animals milk all life, not healthy

dairies have too much calcium that is not fixed into bones unless vit k and vit d are balanced.to us taking high dose vit d3 (high dose is 20.000-40.000iu daily under doctor monitoring) that calcium is not beneficial

animals fed with rubbish food and drugs

[Goldentree]

Steff pls is it adviceable for those of us on vitamin D3 to include vit k2? Am on 5000iu daily. Also if you could advice on daires. Is it ok to take low fat milk and lot fat yoghurt? Ready to quit if they're bad.

[stef2011]

also remember to think about 2 tests few months apart to see the kinetics of increase or decline

[Cjb3695]

I havent taken hbsag quantitative yet. Im trying to see where I can travel to get the test done.

[stef2011]

of course there is because for us vit d goes down immediately as we stop supplements.keep in mind that if pth doesn t lower while increasing vit d we have vit d resistance and vit d is not attaching to receptors

for dr coimbra protocol a doctor for monitoring vit d, pth and calcium is mandatory

[luckyman316]

Stef, if Vitamin D is back to normalized... is there a maintenance amount to take once normalized? Thanks for answering these questions.

[stef2011]

it depends what he wants to try, if just normalize vit d or try dr coimbra protocol

in case of protocol pth is also mandatory to understand if vit d is getting to the cell receptors or not

[mer971]

Steff,do you think when the levels goes back to normal,he should low the unit of vit D, I keep in mind DR Coimbra saying that 10.000 is a normal dose

[stef2011]

you can take both 50.000iu of d3 daily but in this case you need no dairies diet and 2.5l of water per day.after 2 weeks recheck vitd25oh levels and if optimal reduce to 10.000iu daily

or take 10.000iu of d3 daily, in this case no tests or deit required, it is a normal dose, but this will take longer to make optimal vitd25oh levels.with 10.000iu daily you may recheck levels by 2-3 months

[afif120]

do you regularly check your HBsAG quantitative level? If so,  do you mind to share it with us. My son  is treated using viread as well and  wonder how viread works on HBsAG quantitative. Thanks so much

[Cjb3695]

I think you guys are absolutely right. I feel better already. You guys suggest 50,000 a day? Im currently taking 50,000 a week.

[flyinsky]

check olso your calcuim level

[luckyman316]

Stef is correct, this is an issue with lack of Vitamin D... not the Tenofovir. If you are doing 50,000 iu daily then fine but don't stop taking Vitamin D once your level is back to normal. Make sure to keep taking a "maintenance" level to keep your Vitamin D levels STAYING normal. Otherwise, it will go back down again.

Like you, I experienced bone thinning but it happened before I even took Tenofovir. It was from the virus and lack of Vitamin D. It happend VERY quick (in 2 months time). If it makes you feel any better, I am on the Clinical Trial for Tenofovir TAF which is supposed to be used to control bone thinning.... which is primarily happening in HIV patients. So, unless you have HIV on top of Hep B, the drug has been proven not to cause bone thinning in Hep B patients. It's the lack of Vitamin D. However, that new drug will be released probably something in 2016 at the latest.

[stef2011]

this is the result of a whole life without vitamin d in your body, not tenofovir

add also vitamin k 2 (mk-7 type only) which takes ca out of circulation and fixes it into bones, 1000mcg daily at least