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7599415 tn?1392449844

i'm gonna have the peg,in one or two weeks. have some questions

here is my condition.http://www.medhelp.org/posts/Hepatitis-B/my-hbsag-is-35639IU-mi-need-advise-please/show/2216087#post_10625469
1.should i take tenofovir while injecting the peg? because i once heard taking tenofovir could suppress my immune system.
2.should i stop injecting when my hbsag is underdetectable?
3.when should i use hepatitis B vaccine?
your advice will be very important. thanks
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Avatar universal
your example is also very valuable, it looks like using pegintf add on after so many years of nucs have very high success, you confirm on our community the finding of the small trials with sequential add on but using add on only after 5-7years of nucs and not 1-2years of nucs
Helpful - 1
Avatar universal
when we see hbsab rises stable to over 200miu/ml

do contact the guys on mafactive website, they used to make discount if you give feedback on http://www.gcmafresearch.com/
Helpful - 0
Avatar universal

you may also take these supplements to boost response to vaccine, this is a weak formula of gcmaf but approved, cheap and easy to buy.i think the cream on area of hbv vaccine injection and sublingual drops are good.this gcmaf form has no sides effects
http://mafactive.com/mafactive-range/

one member on tdf who had low hbsag 16-25iu/ml for a very long time cleared hbsag after using sublingual gcmaf, this maybe a coincidence but it doesn t harm to try this.
Helpful - 0
Avatar universal
i think alcohol may lower immunity i think it is best to avoid it totally now

yes make another vaccine, we have had 2 trials of monthly hbv vaccine in italy for transplant patients and it worked to make hbsab.they lowered immune suppressive drugs dose and made monthly vaccine

check your hbv vaccine brand and if necessary choose the one with no mercury/formaldeide, they use different names for mercury, choose the brand with the least harmful additives
Helpful - 0
1 Comments
then when can i use some drink?
Avatar universal
Woow. Another HBV survivor. thu i am too late Congratulation!
Helpful - 0
1 Comments
thank you. hope u can make it too
7599415 tn?1392449844
and i have had my second vaccine last week. i plan to have a test next month to check my hbsab. if my hbsab is still not arrive at 200, what can i do? still use the third vaccine?
Helpful - 0
7599415 tn?1392449844
because of my work situation, may i ask if i can drink alcohol like wine or chinese spirits in the meantime i still use tdf
Helpful - 0
Avatar universal
just saw you are in china so zadaxin is available
Helpful - 0
Avatar universal
of all choices stopping peg and making zadaxin+tdf+hbv vaccine is the best

zadaxin is available in few countries, in italy is available
Helpful - 0
Avatar universal
i think studyforhope is the best to help us

personally i think hbsab 33miu/ml is still too low and i would keep peg a little longer if possible using at least one or two courses of hbv vaccine or even better find zadaxin and in this case stop peg and keep zadaxin plus tdf until hbsb rises

another choice is stop peg and keep tdf, check hbsab every week and if stable keep using tdf for 6 to 12 months.hbsab test can be weekly at first then every month to every 3 months once we see it is stable
after 12 months of stable hbsab, even if so low, i think it is ok to stop tdf

in the meantime make your vitd25oh levels optimal at around 100ng/ml. another possibility if zadaxin not available and peg must be stopped would be the use of gcmaf to see if it makes hbsab higher, saisei mirai in japan is the best supplier of this, but it is quite expensive and very few members used it so we cannot say for sure it works.
Helpful - 0
7599415 tn?1392449844
it is my hbsab that is 33 iu, my hbsag is und in the May. so could ii stop peg?
Helpful - 0
7599415 tn?1392449844
i'v had enticavir for 8 years , and tenofovir for 2 years. its obviously below the limit of detection
Helpful - 0
Avatar universal
Some doctors basing on their experience may ask patient if they want to continue if they see it makes sense, in that case it makes definatelly. 48 weeks is just minimal period when you start to see some good results.
Helpful - 0
Avatar universal
Coule a patient decide whether if continue peginterf or just doc who decide?especially in case of getting result of very low hbsag value?
Helpful - 0
Avatar universal
can't you just keep peginf a bit longer until HBsAg becomes und ?
Helpful - 0
Avatar universal
you have to keep tdf until hbsag und and hbsab high stable for 6-12 months

so please repost all results and if you are still on peg, hbsag 33iu/ml, hbsab?
Helpful - 0
Avatar universal
viral load is und being on peg+tdf
Helpful - 0
Avatar universal
And what about your viral load?
Helpful - 0
7599415 tn?1392449844
and my hbsag is 33 for now
Helpful - 0
7599415 tn?1392449844
sorry for not updating so long. after ten months' peg + tenofovir, i've got HBSAB last month from Hepatitis B vaccine(60ug).and i plan to get the other injection until my hbsab reach 100 or more.
my question is that how long can i stop tenofovir? should i take it for one or two years?
Helpful - 0
Avatar universal
Thank you..whatbcan you suggest to totally decrease his hbvdna of 27 and hbsag quantification of 167?
Helpful - 0
Avatar universal
Its 69 ng/ml....what can you suggest
Helpful - 0
Avatar universal
Conversion rate is 2,5 so seems that his level is 69 ng/ml
Helpful - 0
Avatar universal
The unit to use is ng/ml not nmol/l which are confusing, ask lab esult in ng/ml
the target is 100ng/ml and intact pth 10-20pg/ml, i m not sure but 100ng/ml should be 250 or 400nmol/l

To know if sufficient get both result in ng/ml and pth
Helpful - 0
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