Results after about 2 months of VitD3 5000iu and heptec

[April9903]

In April my viral load was 1.7 mil copies/ml.

the results now:-
Fibroscan -- 4.6 kpa
HBV DNA --  55,814 copies/ml
HBsAg (Quantitative) --  2906.99 IU/ml (cut off= 0.05 IU/ml)
25OH Vitamin D3 --  40.8 ug/l

Alt -- 54 u/l -----high (normal 0 - 44)
Ast -- 53 u/l ----high (normal 15 - 41)

Genotype, Precore Mutation, Polemerase mutation have to wait about 2 weeks.
My alt, art is always a little bit high. My doctor already wanted to treat me and she said I have about 50% chance now if I make peg interferon treatment. But I told her I wanted to wait for the time being.
I think vitD3 or heptec or both helped me in dropping so much hbv dna.

my alt and art is high like this for about 2-3 years I think.

[stef2011]

https://docs.google.com/open?id=0B_yFgxI8KNcRY1RfRXNlMFVxVWs

as a reference this is data from a guy adding ntz to intf, he started intf mono and had no response from intf, it looks like he ven had an hbvdna/hbsag increase
ntz add on looks like made an immediate effect on hbvdna, hbeag (hbsag not tested but when hbeag goes down hbsag goes dwon the same)

his doctor thought it was intf having this effect and put him on max intf dose, the sides were so heavy that this guy stopped all therapies, too bad we have such stupid doctors around.

[stef2011]

well the 4 weeks lead in was on hcv trials, maybe it ll work the same on hbv even if starting all at the same time

as regards ntz i checked all trials done on this drug and it was very safe, the higher dosages had the highest response they just did not approve the 3-4g daily dosage because of the costs of big trials required by FDA but one trial in new york used the 4g daily dose on severe aids patients for over an year, soi think you can do just as i did and try doses between 3-4g daily by starting at around 2g daily and slowly increasing to 4g daily and see if you get any sides on gut or creatinine

i had both gut problems, solved by live probiotics and creatinine increase solved by use of fibroguard or coq10+nac antioxidants

[April9903]

Oh...it's a bit late now. I am going to start all at one time.
I'll start taking NTZ tomorrow and evening I'll have Pegasys.
Thanks for the info. Hope you are doing well.

[stef2011]

4-12 weeks of pretreatment with ntz monotherapy are very useful because it makes a drop of hbsag which allows a better intf response when it is added

[stef2011]

no 1 tablet would be just 500mg, not enough for antiviral effect.ntz stays in blood about 5hrs and effective doses were about 3g daily, so it is 1 pill at meals breakfast, lunch,dinner, before going to bed

ntz can have an effect on gut bacteria too so those with weak gut may have diarrea for a few days (i was among these) so it is best to take probiotics or yogurt before starting ntz.i used home made bifidus yogurt and another probiotic i dont remember the name...it was used in ntz trials, the name is in old posts

[April9903]

After long discussions and thinking, I am going to start treatment this Saturday, Pegasys + TDF treatment for 48 weeks. As Stef suggested before  I'll add Ntz also. (this would be without doctor's knowledge) and Vit D3.
@ stef..I have Nizonide 500 from Lupin. I should take 1 tablet a day after food right?

I'll keep you all informed my status.