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Somebody knows about Lutein?
Does somebody know something about this Lutein? Can it be future drug for HBV?
In vitro antiviral activity of lutein against hepatitis B virus.
Department of Hepatology and Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, P.R. China.
Abstract
Despite the availability of an effective vaccine, the hepatitis B virus (HBV) infection and its treatment remains one of the foremost public health problems in the world. The present study was performed in order to investigate the anti-HBV activity of lutein in vitro. The antiviral activity of lutein was examined by detecting the levels of HBsAg, HBeAg and extracellular HBV DNA in stable HBV-producing human hepatoblastoma HepG2 2.2.15 cells. It was found that lutein effectively suppressed the secretion of HBsAg from HepG2 2.2.15 cells in a dose-dependent manner, and it also suppressed the amount of extracellular HBV DNA. A luciferase reporter gene assay was used to determine the effects of lutein on the activities of HBV promoters. The results showed that lutein inhibited the activity of HBV full-length promoter (Fp). These data indicate that lutein possesses an anti-HBV activity and exerts its antivirus effects via inhibition of HBV transcription. Copyright © 2010 John Wiley & Sons, Ltd.
Copyright © 2010 John Wiley & Sons, Ltd.
PMID: 21031619 [PubMed - in process]
More on Lutein:
Where to Find Lutein
Though lutein is deposited into many areas of the body prone to free radical damage–like the eyes and skin–it cannot be manufactured by the body.
The only way to take advantage of lutein's antioxidant benefits is by consuming it–or, in the case of a growing number of skin care products, by applying it to the skin.
You can find lutein…
…in vitamins and nutritional supplements
…in raw foods
…in fortified foods
…in topical applications
http://www.luteininfo.com/
In vitro antiviral activity of lutein against hepatitis B virus.
Department of Hepatology and Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, P.R. China.
Abstract
Despite the availability of an effective vaccine, the hepatitis B virus (HBV) infection and its treatment remains one of the foremost public health problems in the world. The present study was performed in order to investigate the anti-HBV activity of lutein in vitro. The antiviral activity of lutein was examined by detecting the levels of HBsAg, HBeAg and extracellular HBV DNA in stable HBV-producing human hepatoblastoma HepG2 2.2.15 cells. It was found that lutein effectively suppressed the secretion of HBsAg from HepG2 2.2.15 cells in a dose-dependent manner, and it also suppressed the amount of extracellular HBV DNA. A luciferase reporter gene assay was used to determine the effects of lutein on the activities of HBV promoters. The results showed that lutein inhibited the activity of HBV full-length promoter (Fp). These data indicate that lutein possesses an anti-HBV activity and exerts its antivirus effects via inhibition of HBV transcription. Copyright © 2010 John Wiley & Sons, Ltd.
Copyright © 2010 John Wiley & Sons, Ltd.
PMID: 21031619 [PubMed - in process]
More on Lutein:
Where to Find Lutein
Though lutein is deposited into many areas of the body prone to free radical damage–like the eyes and skin–it cannot be manufactured by the body.
The only way to take advantage of lutein's antioxidant benefits is by consuming it–or, in the case of a growing number of skin care products, by applying it to the skin.
You can find lutein…
…in vitamins and nutritional supplements
…in raw foods
…in fortified foods
…in topical applications
http://www.luteininfo.com/
Lutein, an herbal medicine, provides nutritional support to eyes and skin etc.
http://www.luteininfo.com/about
Following links provides info re its connection with HBV but only on research stage:-
LUTEIN Overview Information
http://www.webmd.com/vitamins-supplements/ingredientmono-754-LUTEIN.aspx?activeIngredientId=754&activeIngredientName=LUTEIN
Phytotherapy Research
In vitro antiviral activity of lutein against hepatitis B virus
http://onlinelibrary.wiley.com/doi/10.1002/ptr.3155/abstract
Page 386
Alternative Medicine
http://books.google.com/books?id=95RQkiCxTGEC&printsec=frontcover#v=onepage&q&f=false
There are many herbal medicines from Asia such as India, Pakistan, China, etc. claiming able to cure HBV. What I expect to see is the clinical proof.
http://www.luteininfo.com/about
Following links provides info re its connection with HBV but only on research stage:-
LUTEIN Overview Information
http://www.webmd.com/vitamins-supplements/ingredientmono-754-LUTEIN.aspx?activeIngredientId=754&activeIngredientName=LUTEIN
Phytotherapy Research
In vitro antiviral activity of lutein against hepatitis B virus
http://onlinelibrary.wiley.com/doi/10.1002/ptr.3155/abstract
Page 386
Alternative Medicine
http://books.google.com/books?id=95RQkiCxTGEC&printsec=frontcover#v=onepage&q&f=false
There are many herbal medicines from Asia such as India, Pakistan, China, etc. claiming able to cure HBV. What I expect to see is the clinical proof.
very interesting, thanks
are you able to get full article?the dose active in vitro?the people in the study should have some animal study too because many compounds are active in vitro but no activity in vivo
we should find best brand of natural lutein supplements with not even minimum toxicity for liver/no alcool in it
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