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Avatar universal

Starting IFN next month.

Hi all,

I will be starting a mono IFN therapy in 5 weeks time. After deliberating about it for the last 6 months, I think I need to at least give it a try. I just missed the trial for IFN/TDF in FEB this year because my viral load was too low for this trial (one of the criteria).

Lastest blood test today confirm HBV DNA has increased from 200iu/ml (2 logs) to 20000iu/ml (4 logs) in 3 months. These are approx. numbers and I didn't ask for a print on the result. We don't measure HBsAg in this hospital, which is not good. HBV DNA fluctuating between these number for the last 12 months.

Latest ALT steady at 40, AST at 34, GGT 16, ALP 52 and Bilirubin at 7.

My history:
Last ETV pill was on Dec 2011. During this treatment (somewhere in between stopping), I convert from HbeAg-Positive to HBeAg-Negative, e-antibody negative to e-antibody positive. Doctor ask me to stop after approx. 18 months. It was not my choice. I think it's because my HBV DNA was UND for a few months and my ALT value was below 40.








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Avatar universal
Totally agree with you.
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10915849 tn?1415112928
Congratss
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Avatar universal
happy for you
you and safi used deferent treatement and deferent diet(safi get married,you want to be cure and think positive when you use peginterf both of you get ride of virus ,i think the will for cure is the best booster of immune system
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Avatar universal
Thank you all.

We actually do not know if diet alone (ridiculously changing diet and lifestyle) can reduce HBsAG to non-detected and create antibodies. The 2% annually cured from HBV could be the one with these healthy mindset and healthy habits that reversed the disease. This is only a speculation.

However, if you are on meds for HBV, it is more imperative that you live healthy and help boost your immune more as the meds (whether IFN or anti-virals) are kick starting your body and need more boost (exercise and healthy eating, along with supplements), let alone you suppressing it further by smoking, drink alcohol and eating unhealthy junk food.

I must admit andrey19 that I was more than suprised to see HBsAB of 943. It starts with 55 (week 36 IFN), then 255 (week 45), then 353 (week 48) and 953 (week 64).

Also please note I was on a reduced dosed of IFN - 2 weeks on 180mcg, 26 weeks on 135mcg and 20 weeks on 90mcg.

Good luck to all.


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Avatar universal
Another member cured! Fantastic, I hope one by one we will get out from here
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Avatar universal
your anti-hbsag level is amazing! Congratulations.
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