Read the thread started by Mei. You two have a similiar presentation:
Since typing the same stuff takes alot of time. Here's a cut and paste of the relevant points to your presentation:
Sometime prior to Dec 2006, you were probably in the inactive phase of the disease before with eAntigen negative, eAntibody positive, low DNA, and normal LFTs and ALTs.
If you DNA jumped from low to 107,000 IU/ML (which is a sign of the disease breaking through immuno-control) then to 487,165 IU/ML, with elevated ALTs, those are classic signs of a eAntigen negative active disease. This is a classic sign of the core-promoter mutant strain, which is quite common. Like 50% of all carriers eventually have this mutation. This is the re-activation that carriers have to look out for. If this is you, you should treat. And start soon, try to cut down the virus' replicating abilities. Treatment in such cases are long-term. Consider combo treatment to reduce the risk of resistance. Lamivudine monotherapy should not be used because of its poor resistance profile.
With a 50 miilion viral load, you could do genotyping now to check for the pre-core or core-promoter mutation. Ask your doctor for that. It's probably the core-promoter.
With an eAntigen negative disease, treatment is basically long term. I think most doctors recommend antivirals because it has minimal side effects and easier to tolerate long term as opposed to Peg Interferon (some on the HepC forum referred to Interferon as doing hard time).
Combo treatment is taking 2 antivirals to cross protect against resistance. It attacks the virus on 2 fronts to reduce it adaptive abilities. Important because you may may to take antivirals for the rest of your life. Always think of the long term.
Discuss the above with your doctor. Good luck.
And hope you stick around and let us know how you are doing.