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Urgent Advise for Entecavir Usage

Dear Friends,

I am a chronic Hepatitis B patient (29 male from Turkey) and I need your help for the medicine (Barclude 0.5mg) usage schedule and some suggestions (if you have).

Before you answer, I would like to share my story and my daily life.

I learned that I am a chronic Hepatitis B patient in last day of July 2013 after the Elisa test for the marriage (I got married in September). I was shocked because I have a fit body, eat quality foods, and I do not have any illness or discomfort.

Then I have done some test including HBV DNA. The results are;

HBSAG: 492
HBEAG: 882
ALT: 86 (it should be 15-60 for healties)
BILIRUBIN: Normal
ALBUMIN: Normal
HBV DNA: over 170 millions (could not be counted. It is may be over billions)
ULTRASOUND: TOTALLY NORMAL

Then after 2 months later I have been done biopsy. The results were not good:

FIBROSIS: stage 3
HAI: phase 11

My doctor is one of the leading professors on Hepatitis B in the world. He and his assistant started treatment with Baraclude 0.5mg (Entecavir) 2 days ago. I will buy the medicine and start taking today. My doctor told me that it does not differ that what time I take the medicine. The only important think is that I should take it everyday in the same time.

My main question is “ At what time should I take the medicine for the best results? ”. I need the suggestions of Hepatitis B patients using Baraclude.

I know it differs for everybody because everybody has different daily life routine. So, before write your answers please read below and see my daily life routine and the natural supplements for Hepatitis B.

MORNING
07:00 am ; eat one dessert spoon of black seed (nigella sativa) with honey and continue sleeping
08:00 am ; eat one dessert spoon of honey-royal jelly-propolis-bee pollen mix and continue sleepig
08:45 am ; wake up and breakfast (bread+white cheese+juice) plus garlic
09:30 am ; start working (by computer in my office)

NOON
12:00 am ; lunch (with vegetables and a little bit meat)
13:00 pm ; start working (by computer in my office)

AFTERNOON
16:00 pm ; a little bit junk food (such as; biscuit)
17:30 pm; stop working

EVENING
18:30 pm ; at home
18:45 pm ; dinner (with vegetables or fish ) plus garlic
19:30 pm ; fitness (15min treadmill and 7 exercises OR swimming )
21:30 pm ; stop fitness

NIGHT
22:00 pm; at home, watch TV (or internet surfing), and eat some fruit
23:00 pm; take natural turmeric (curcuma longa)
23:30 pm; eat one dessert spoon of honey-royal jelly-propolis-bee pollen mix
24:00 pm; go to bed

Above you see some natural supplements (such as; black seed, turmeric, royal jelly-propolis and etc.). All the natural supplements are for Hepatitis B and I have started taking them for 3 months (after I learned I am patient). They have anti-viral effects and renewing the liver cells (I hope).

When it comes to question: “AT WHAT TIME SHOULD I TAKE BARACLUDE FOR THE BEST RESULTS?” I need the suggestions of Hepatitis B patients using Baraclude (Entecavir). And also I am very open your suggestions and sharings about Hepatitis B to get rid of this or to be more comfortable with this.

Thank you for your reading this stupid and long writing.
Best Answer
Avatar universal
Entecavir is usually taken with an empty stomach, that is, two hours before a meal and two hours after a meal. So some patients take it before going to bed. However, this is not suitable for everyone, as some patients report that they have difficulty falling asleep.
So maybe take Entecavir two hours after breakfast or two hours after lunch?

Don't be too concerned about taking the medication at the same time, but a routine does make you remember to take it everyday.

If you are taking antiviral treatment for the first time, the empty stomach rule is not that important, according to the label information.
43 Responses
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Avatar universal
Did you taken interferon before your Hepatitis B was cured
Helpful - 0
Avatar universal
Hello,

I think yes, the photos are very similar to black seed.
Helpful - 0
Avatar universal
Is black seed cumin same as Indian's Kalonji or Nigella?
Helpful - 0
Avatar universal
yes alt over 200 increase inflammation which in turn increase stiffness, there are new ways to determine correct fibroscan per abnormal alt but i d wait 3-6 months after a alt flare or simply recheck by 6 months

fibroscan is the sum of fibrosis, inflammation and when present nodules and fatty liver too, so when reading results all this must be taken into account

empty stomach needed for best accuracy
Helpful - 0
Avatar universal
@safisifa..

i remeber me reading somewhere thath fibroscan/bviopsy results are not accurate at all when ALT AST are so high.. high alt means liver is suffering in that moment so it can be stiff... so i would not be 100% you are F3..

am i rigth stef?
Helpful - 0
Avatar universal
if you change life style/diet like you see many others in the community your liver will be back to 0 fibrosis and full health in few years, 1-2 years if etv+diet+vitamins+antioxidants
Helpful - 0
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