Vit D3 and side effects

[OrientS]

Finally i found a pharmacy in my country (saudi arabia) in Jeddah that sells vit d3
It was in drops form , each drop contains 400 iu of vit d3 ..
The problem in the presecription which attached withthe drug written a risky side effects can damage the kidneys .. And the huge amount of vit d3 ( 1000-3000 iu) it has poisinous that lead to negatively affects on the liver and kidney functions !!!

I was planning to take 5000 iu of vit d3 per day .. However i prefer to lower the quantityper day ..

[stef2011]

thank you so much for this very clear presentation, i ll post it separately in a new thread

finally we have a clear indication for correction of deficency with 50000iu weekly or 10000iu daily which is exactly the only dose that works for me and my sister, 5000iu didn t work and levels stayed lower than 50ng/ml

[stef2011]

please see if you find any article on cccdna on combos, i have found only once old article on interferon+adefovir with measure of cccdna, of course this is the most potent reported but probably interferon+tenofovir is more potent

i am particularly interested to see my combo tenofovir+entecavir effect on cccdna, i could not find even animal studies on this

[StephenCastlecrag]

For those of you interested in Vitamin D and Statin, there is an excellent talk available on the AASLD website:
http://www.aasld.org/education/bolm/Pages/default.aspx

It is must informative.

[stef2011]

use tan beds, 1000iu is useless, tan bed 3 times a week can rise vitd3 very fast to 40-50ng/ml

[kac366]

In September I use to take vit d3 1000 every day and I  notice  
•Metallic taste  ( the development of unpleasant metallic taste
•Dry mouth thick and sticky saliva
* No sleeping at all and cofusion in the night time
I stopped after 3 weeks when i notice and all is gone.

However Recently I cheked my VIT D3 level which became 32ng and my doctor descrtibed 1000 iu daily on life I started again and as soon as i started all the above came back which I stppoed again and i will see how it goes.

Is any one experience sleeping disorder and dry mounth with vit d3

[stef2011]

the best way to take vit d is by checking vit d level every 3 months and calcium in urine as well instead of calcium in serum, this is because calcium in urine gets higher much before calcium in serum

rise of calcium is not toxic or makes any damage until a level of 15 in serum is reached and even after you reach this level it needs a lot of time to make damage, so making damage by taking vitamind is very very difficult especially checking the levels

[stef2011]

that is 50000iu for several months, we dont need that much doses are from 5000 to 10000iu daily

i just got the result form the good lab and my vit d is 68ng/ml, the 26ng/ml result was complitely wrong, i have been taking 20000iu daily for 2,5days

the problems with calcium rise are only when vit d 25oh reaches 150-500ng/ml, this level cannot be reached unless taking 50000iu dailyfor more than 6 months

[enolia]

It is probably just old information...You will find toxicity risks everywhere on the internet. Wikipedia says this: ''...sustained intake of more than 1250 micrograms/day (50,000 IU) can produce overt toxicity after several months;[''
You better be careful and moderate in everything.

[4est]

:) .. this ca be a important change, even the brand can be a important change, but we will see :)

[April9903]

When I started in May I took the brand soft gel type for about 3 weeks. Then I changed to  tablet form.

Only now I realized the change I have done. I am sure soft gel type is better than the tablet form. I'll change back to soft gel type. Soft gel type absorb better vit d3.

[April9903]

This test is always done in the same lab. It's not sun exposure or diet, but it could be the exercise. Because I don't exercise regularly...sometimes i do it for 1-2 months then I stop again for 3-4 months and so on. I am not sure this is the reason. Now I am thinking to start doing the exercise again and if the result changes dramatically in December test then it must be the exercise.

[4est]

OK, I understand.

Anyway as you say it is strange, if you don't change anything (sun exposure or diet, or exercise ...).
the test was on the same lab ?

[April9903]

No. I started taking vit d3 in May and June I made the test. June test is just one month after taking vit d3 5000iu per day.

Actually I also think this is strange. I didn't change anything particularly. I'll check again in December.

[4est]

so before starting D3 supplement you have 9.4 (june) and during the first month of D3 supplement you go at 7.5 (august) and after 3 month you are at 8.6 ?

this is really strange, do you change something in you diet or habit ? (you stay more in sun in june then in augurst ? ...)

[April9903]

Not yet but I wish to start soon.
You can check the following link.

http://www.medhelp.org/posts/Hepatitis-B/Results-after-about-2-months-of-VitD3-5000iu-and-heptec-/show/1601656#post_7327334

[grmr]

just for my acknoledge are you on any therapy?

[April9903]

25OH Vitamin D3 --  40.8 ug/l   in September 2011

[grmr]

what about vit 25doh values???

[April9903]

Just checked the numbers.
in June ( I think it's one month after I started taking vit d3 5000iu per day )
9.4  mg/dl  ------normal ------ 8.5-10.1 serum ( Ref. Range )

in August    7.5 mg/dl  ------low ------ 8.5-10.1 serum ( Ref. Range )

in Nonember    8.6 mg/dl --------normal------8.5-10.1 serum ( Ref. Range )

[April9903]

I have checked calcium levels every month since I started taking vit d3 5000iu per day. On one month my calcium level is even lower than the range. Another month it's just a little above the lower range.
At the moment my doctor in my home country is abroad and will be back on 15 of this month. I will see him when he's back.

[4est]

do you double check the last result of vit d (vitd25oh = 26ng/ml) ? (maybe a false result or a false supplement)

[stef2011]

by the way when i started in jan 2010 i used 5000iu daily and i could only rise vit 25oh to 25-35ng/ml in 4-5months, the response varies according to bmi and cronic infections, if obese vit d wont rise unless 10000iu are used

[stef2011]

absolutely not, you d better use 5000iu daily and check calcium serum or urine in 4 weeks
you have high calcium from start but if you dont have paratiroidism disease your body will keep calcium in balance

calcium can rise to abnormal 15 without any damage, it is having calcium at 15 for months to make damage

all this stupid and wrong info about vit d is written like if we are so stupid to take it without double checking all the correct parameters

by the way if you drink about 2-3 liters of water daily you can lower calcium  of 1-1.5 points, calcium increase is not a problem at all and it is treated by drinking water...there are also many drugs to lower calcium but we dont need this at all
calcium is also a part of immune system response so better keep it between 9 and 10 when possible

[grmr]

by the way stef.. I began this mornin to take 5000IU vit D3 pills bought on line.. my vit 25Doh was 23 and calcim around 10.... i now take one pill everty two days (1 day yes and 1 no)... then I'm planning to re.check vitd and calcim in 2 months.. won't this be hazardous?