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What can of result can I expect from my liver biopsy?
Hi,
The doctor has told me with confidence that I have chronic hep b based on the following test results:
Hbsag pos
Anti hbs neg
Anti hbc igm neg
Hbeag pos
Viral load around 6000
Hbv dna > 110000000
Gpt, got levels around 200-300
Fibroscan normal
Ultrasound normal
I've already had my biopsy done but I am still waiting for my results. Based on the above information, does anybody have any ideas of the most possible outcomes?
Liver damage? Outlook? What kind of therapy will I most likely face? The mentioned that I will have to choose between pills or injections; he said that if I take pills, there is always the possibility that the virus can become immune to the meds, whereas taking injections is guaranteed greater success but with more side effects. Is this true?
Has anybody heard of a 48 shot regiment for chronic hep b therapy? The doctor makes it sound like its going to work 100% whereas taking meds would be risky.
Thanks for the help.
The doctor has told me with confidence that I have chronic hep b based on the following test results:
Hbsag pos
Anti hbs neg
Anti hbc igm neg
Hbeag pos
Viral load around 6000
Hbv dna > 110000000
Gpt, got levels around 200-300
Fibroscan normal
Ultrasound normal
I've already had my biopsy done but I am still waiting for my results. Based on the above information, does anybody have any ideas of the most possible outcomes?
Liver damage? Outlook? What kind of therapy will I most likely face? The mentioned that I will have to choose between pills or injections; he said that if I take pills, there is always the possibility that the virus can become immune to the meds, whereas taking injections is guaranteed greater success but with more side effects. Is this true?
Has anybody heard of a 48 shot regiment for chronic hep b therapy? The doctor makes it sound like its going to work 100% whereas taking meds would be risky.
Thanks for the help.
I recommend that you read http://www.aasld.org/practiceguidelines/Documents/Bookmarked%20Practice%20Guidelines/Chronic_Hep_B_Update_2009%208_24_2009.pdf before you see another doctor. That way, you can make better informed decisions.
Hi,
how old are you?
34
When did you get married?
Married 6 years ago
How and when did you discover that you have Hep B?
In the middle of May 2010, I started getting muscular aches and pains in the mornings. Felt very much like shoulder, wrist, and finger sprains. I couldn't raise my arms above my shoulders in the mornings. During that time I thought I had some kind of never damage or something. The body aches lasted for about a month before I decided to go see a doctor. The doctor gave me a blood test and that's when she discovered the elevated ALT and AST levels and sent me to see a liver specialist. By the end of June most of the aches and pain had subsided when I went to see a specialist. That's when I found out I was HBsag positive.
The specialist tells me that he is pretty confident that I have Chronic Hep B based on the test results above.
How do I feel these days?
I actually feel like I'm almost 99%, except for some mild pain once in while in my wrists, and the never ending thoughts of having the virus inside me and my future.
Once the liver biopsy results come in and I get the doctor's recommendations I plan on seeing another doctor for a second opinion.
how old are you?
34
When did you get married?
Married 6 years ago
How and when did you discover that you have Hep B?
In the middle of May 2010, I started getting muscular aches and pains in the mornings. Felt very much like shoulder, wrist, and finger sprains. I couldn't raise my arms above my shoulders in the mornings. During that time I thought I had some kind of never damage or something. The body aches lasted for about a month before I decided to go see a doctor. The doctor gave me a blood test and that's when she discovered the elevated ALT and AST levels and sent me to see a liver specialist. By the end of June most of the aches and pain had subsided when I went to see a specialist. That's when I found out I was HBsag positive.
The specialist tells me that he is pretty confident that I have Chronic Hep B based on the test results above.
How do I feel these days?
I actually feel like I'm almost 99%, except for some mild pain once in while in my wrists, and the never ending thoughts of having the virus inside me and my future.
Once the liver biopsy results come in and I get the doctor's recommendations I plan on seeing another doctor for a second opinion.
how old are you? When did you get married? How and when did you discover that you have Hep B?
The thing is you tested negative for IgM anti-HBc... (this is known to be an unreliable test) which may indicate that you are in the early stages of acute Hep B or you are quite chronic.
I did not see the 6000 figure anywhere, so I'm settled on the other one that I saw readings for.
The other readings, high ALT (ALT should be a max of 30, for men) and extremely high HBV DNA viral load are patterns seen more often in acute Hep B, rather than in chronic.
If I were you, I would rest for a while (how do you feel these days?) , and re-do all the blood-work tests after a month (i.e. not biopsy, ultrasound, fibroscan). In the mean time, I hope you educate yourself about Hep B.
The thing is you tested negative for IgM anti-HBc... (this is known to be an unreliable test) which may indicate that you are in the early stages of acute Hep B or you are quite chronic.
I did not see the 6000 figure anywhere, so I'm settled on the other one that I saw readings for.
The other readings, high ALT (ALT should be a max of 30, for men) and extremely high HBV DNA viral load are patterns seen more often in acute Hep B, rather than in chronic.
If I were you, I would rest for a while (how do you feel these days?) , and re-do all the blood-work tests after a month (i.e. not biopsy, ultrasound, fibroscan). In the mean time, I hope you educate yourself about Hep B.
Here is my complete blood count:
http://i29.photobucket.com/albums/c297/vsengdara/utf-8BSU1HMDEwMjctMjAxMDA3MjYtMTQ0MS5qcGc.jpg
http://i29.photobucket.com/albums/c297/vsengdara/utf-8BSU1HMDEwMjctMjAxMDA3MjYtMTQ0MS5qcGc.jpg
Sorry about the mistakes, here are links to pictures of my lab work. Hope you can give me a better prediction of my future.
http://i29.photobucket.com/albums/c297/vsengdara/IMG01025-20100726-1422.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01023-20100726-1421.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01022-20100726-1420.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01021-20100726-1420.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01025-20100726-1422.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01023-20100726-1421.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01022-20100726-1420.jpg
http://i29.photobucket.com/albums/c297/vsengdara/IMG01021-20100726-1420.jpg
Sorry about the mistakes, here are links to pictures of my lab work. Hope you can give me a better prediction of my future.
[IMG]http://i29.photobucket.com/albums/c297/vsengdara/IMG01025-20100726-1422.jpg[/IMG]
[IMG]http://i29.photobucket.com/albums/c297/vsengdara/IMG01025-20100726-1422.jpg[/IMG]
Agree Sharp7 completely.
does anybody have any ideas of the most possible outcomes?
--G1S1 or better.
Liver damage?
--Little.
Outlook?
--Depends.
What kind of therapy will I most likely face?
--Could be just monitoring.
The mentioned that I will have to choose between pills or injections; he said that if I take pills, there is always the possibility that the virus can become immune to the meds, whereas taking injections is guaranteed greater success but with more side effects. Is this true?
--Yes.
Has anybody heard of a 48 shot regiment for chronic hep b therapy?
--No.
does anybody have any ideas of the most possible outcomes?
--G1S1 or better.
Liver damage?
--Little.
Outlook?
--Depends.
What kind of therapy will I most likely face?
--Could be just monitoring.
The mentioned that I will have to choose between pills or injections; he said that if I take pills, there is always the possibility that the virus can become immune to the meds, whereas taking injections is guaranteed greater success but with more side effects. Is this true?
--Yes.
Has anybody heard of a 48 shot regiment for chronic hep b therapy?
--No.
"Viral load around 6000
Hbv dna > 110000000 "
This can't be... they both refer to the same thing. Can you post exactly what it says on the report, including units?
Biopsy may not have been necessary, given normal fibroscan and ultrasound reports. But, since you got it done already, it's fine.
Don't be in a hurry to begin medications: Reconfirm your HBV markers once again, and check your ALT frequently for a couple of months.
Do not decide between pills and injections until you get HBV genotyping done. These injections are useful only in 2 of the 4 common genotypes. Meds... once you begin, if you have to stop for any reason (other than a stable cure) will backfire badly.
Many of us here, including me, have done peginterferon injections. It has worked for some, and not worked for others.
Bottom line (this is just my opinion, others here and elsewhere may disagree): do not be in a hurry to start medicating. Do spend time in understanding the disease, understanding your status, understanding the options, etc.
Hbv dna > 110000000 "
This can't be... they both refer to the same thing. Can you post exactly what it says on the report, including units?
Biopsy may not have been necessary, given normal fibroscan and ultrasound reports. But, since you got it done already, it's fine.
Don't be in a hurry to begin medications: Reconfirm your HBV markers once again, and check your ALT frequently for a couple of months.
Do not decide between pills and injections until you get HBV genotyping done. These injections are useful only in 2 of the 4 common genotypes. Meds... once you begin, if you have to stop for any reason (other than a stable cure) will backfire badly.
Many of us here, including me, have done peginterferon injections. It has worked for some, and not worked for others.
Bottom line (this is just my opinion, others here and elsewhere may disagree): do not be in a hurry to start medicating. Do spend time in understanding the disease, understanding your status, understanding the options, etc.
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