cure!!!

[jagado]

s hepatitis b cn be cure nw a days?

[stef2011]

40% is in hbeag negative, hbeag positive should have higher percentages but as you know if you are already on a potent nuc for 1-3 years you get probably hbeag neg by the time you add interferon

anyway add on of interferon from stable nuc with hbvdna und makes 40% clearance by 48weeks and extremely low hbsag in the remaining which are continuing therapy and proabbly clearing by 96 weeks.

only 1 patient on lam+adv was non responder, maybe use of etv+tdf could make him responder

[hbv]

in same situation of HbeAg- then still chances are 40% when dna recently UND?

[hbv]

in same situation of HbeAg- then still chances are 40% when dna recently UND?

[stef2011]

yes interferon+tenofovir or interferon+entecavir has a cure rate of 40% in 48weeks if hbvdna was already undetactable from long time

starting interferon+tenofovir directly with hbvdna detactable has a lower clerance rate of 26% in 48weeks