Aa
help needed regarding HB ve treatment
Dear Freinds
I am 33 years old lady. One and half year erlier i was dignosed HB+ve patient at the time i consulted with different two three physicians they told me that i B+ve but it is bellow of range. I am worried about my health.
i am requesting you kindly suggest me the treatment or any injection which is helpful to elminate the HB virus.
Hope to hear from any body soon
I am 33 years old lady. One and half year erlier i was dignosed HB+ve patient at the time i consulted with different two three physicians they told me that i B+ve but it is bellow of range. I am worried about my health.
i am requesting you kindly suggest me the treatment or any injection which is helpful to elminate the HB virus.
Hope to hear from any body soon
MEDICAL PROFESSIONAL
Even people who clear the virus on their own, even if they clear it in the acute stage ( 90%), still have the virus in their liver. They do not SHOW the surface antigen, because the anti HbS binds to it, forming immuncomplexes, if the antibody is in excess. It is well published that by sensitive methods that you can find traces of HBV DNA in the liver and even in the serum many years after the acute disease. It is the HBV minichromosome - the cccDNA- that is very stable. For practical purposes - why this is important to know- see my comment #3 above.
How do you have the virus if you have no S antigen and S antigen antibodies?
Are you saying those that cleared the virus on their own still have the virus?
Are you saying those that cleared the virus on their own still have the virus?
I had active HepB twice...First, Just because you go from having the active phase of HepB into an inactive phase does not mean that you "clear" the virus. Second, I've known more than one person who has had HepB twice: the "active" stage. Both bouts of HepB were closely monitored and treated by the same doc and showed the same results. If you're having a problem understanding this issue, go ask your doc for some help. I can't explain it any better. Good luck. Pauly
This answers the question of getting Hepb twice.
"If a patient is diagnosed with acute hepatitis B and then resolves the infection, can the patient ever get hepatitis B again?
Generally speaking, no. It is possible, however, for a person to have two different HBV infections, the second due to an HBV variant or a different HBV subtype."
http://www.immunize.org/catg.d/p2021b.htm
"If a patient is diagnosed with acute hepatitis B and then resolves the infection, can the patient ever get hepatitis B again?
Generally speaking, no. It is possible, however, for a person to have two different HBV infections, the second due to an HBV variant or a different HBV subtype."
http://www.immunize.org/catg.d/p2021b.htm
I'm curious how you got HBV twice. If you got it once and cleared you would have the natural antibodies to get it again.
If you had it once and didn't clear you will have it so I don't know how you get it twice.
If you had it once and didn't clear you will have it so I don't know how you get it twice.
MEDICAL PROFESSIONAL
If the vage expression "cleared the virus" is is used in HBv disease it can mean many different things:
1. Loss of e-antigen , appearance of anti Hbe mostly accompanied by a dramatic reduction in viral laod in serum and in the liver.
This generates the "inactive carrier" status. After years however a certain percentage will develop e-Ag negative hepatitis. You have to watch this.
2. A drop in the viral laod to "undetectable" by the assay used in the particular case. The surface antigen remains pos. A flare of HCV can also cause temp. HBV negativity.
3. A drop in viral load to undetectable and a loss of surface antigen, often followed by anti HbS. This dramatically improves the outlook of the disease, inflammation will be low to none, progression to cirrhosis halted. But the virus is still in the liver and elsewhere in small amounts, in the form of the so called cccDNA. But the cancer risk is still elevated, depending on how long the disase existed before this seroconversion. Furthermore, immunosupressive treatment for rheumatic disorders or malignancies will reactivate the virus and the hepatitis will be back.Therefore your treating doctor will give you antivirals for prevention in such cases.
1. Loss of e-antigen , appearance of anti Hbe mostly accompanied by a dramatic reduction in viral laod in serum and in the liver.
This generates the "inactive carrier" status. After years however a certain percentage will develop e-Ag negative hepatitis. You have to watch this.
2. A drop in the viral laod to "undetectable" by the assay used in the particular case. The surface antigen remains pos. A flare of HCV can also cause temp. HBV negativity.
3. A drop in viral load to undetectable and a loss of surface antigen, often followed by anti HbS. This dramatically improves the outlook of the disease, inflammation will be low to none, progression to cirrhosis halted. But the virus is still in the liver and elsewhere in small amounts, in the form of the so called cccDNA. But the cancer risk is still elevated, depending on how long the disase existed before this seroconversion. Furthermore, immunosupressive treatment for rheumatic disorders or malignancies will reactivate the virus and the hepatitis will be back.Therefore your treating doctor will give you antivirals for prevention in such cases.
If I was you, I'd get a copy of the lab results and sit down with your doc and let him explain your situation to you. Otherwise you might make a decision that could haunt you later on. Are you experiencing any symptoms: fatigue, jaundice, flu like symptoms, and unusual aches or pains? They do have tx for HBV and luckily for you ( if you need it) it is much simpler than is tx for our little sickness: HCV. I've had HBV twice and it isn't someting to take lightly. Go to a gastro or a heptologist and get the real deal: a copy of your labs and an explanation of what they mean and what if any tx is indicated!!! Best of luck, good wishes... Pauly
Just because you have HBV doesn't preclude you from getting it a second time, take my word for it. The second time was nearly fatal. years later, when I found out that I had contracted HCV, I was told that I had cleared the HBV and I wouldn't need the tx for it. Have you ever had HepB, do you know what the process of getting over the active phase of it is? Many who have had HepB and not have had HepB do not understand the difference between them, they're significant. Pauly
Yes I have Hepb and I still don't understand how you can get it twice.
It seems it is possible that your 2nd bout of acute HBV was actually acute HepC.
If you get HepB and clear it then you have antibodies to the virus (you are HBsAb+) and you are then immune.
It seems it is possible that your 2nd bout of acute HBV was actually acute HepC.
If you get HepB and clear it then you have antibodies to the virus (you are HBsAb+) and you are then immune.
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