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my anti hbs reactive after 8 months of tenefovir
please guide doctor guide me for anti hbsag and report show anti hbs positive is it mean anti hbsag positive i am on tenefovir from last eight months please guide
my last two consecutive blood work shown hbv dna not detected, alt in 40's range, (alt was as high as in hundreds before, the dr. was more nervous than I was), hbsag non-reactive, hbsab reactive, immune to hepatitis B virus. the Dr. did tried to find my genotype back in 2009, but the lab was not able determine my genotype, possible due to low hepatitis B virus activity. now the dr. told me I am converted, in a few more weeks, I will go draw blood one more time for 6 months after stopping the viread pill, if everything stays the same, then probably i am officially off the hook.
A person who I talked with also had ALT spike just before natural seroclearance. She had HBsAg and HBsAb+ for many years, no treatment.
Many HBV patients do have both HBsAg and HBsAb positive at the same time. Whether you will clear HBsAg is difficult to predict unless your serum HBsAg is < 100 iu/ml. Having HBsAb positive does not predict that you will clear HBsAg. You can research this topic by googling "simultaneous HBsAg HBsAb positive".
1 Comments
please help me that do tenfovir have some role in anti hbs postive report and do in my hbsag quantitative please tell me about the role of medicine
not uncommon means that this is common case means this report has some
meaning means do i have chance of becoming hbsag negative in near future
meaning means do i have chance of becoming hbsag negative in near future
i think my hbsag positive but the anti hbs is positive then what does the report mean do anti hbs reactive mean any thing means will i become hbsag negative in near future
Your doctor should base his decision on HBsAg only. Whether HBsAb is positive or negative is not important, in my opinion.
4 Comments
so anti hbs postive mean nothing what does it mean do i have chance to become hbsag negative in near future please guide
Are the other measurements available, such as quantitative of hbsag, hbv dna pcr, ast, alt, if your hbsag is out numbering your hbsab, and do you have the baseline before take the medication? maybe your immuse system will still need more time to make more hbsab, or the lab measuring equipment has limitation, do you experience any change/effects body recently? Once my hbsab became reactive, i have not experience any hbv related symptoms.
i have f4 fibrosis with second liver biopsy i ahve undetected hbv liver enzymes are high and my dna was always low 47 iu/ml before tenfovir and 461 before entecavir since then doctor have done two liver biopsy for high liver enzymes and now anit hbs positive result does it mean i have chance of being negative in near future please do guide
I was looking to see if there is any similarity, in my case, my hbv dna went undetected (maybe due to limit of equipment, the lab i used can only go down to 29iu/ml) for a number of years, hbsag reactive, then all the sudden, hbv dna spike to 1800 ui/ml, very high ALT, the dr. was very concerned, and ordered another blood work, about two months later, hbv dna went undetected, and another two months later, hbsag non-reactive, and hsbab reactive, ALT then lower. all this just happen in the span of 4 to 6 months, and since not feasible to do blood work daily or weekly, I do not know if I also have hbsag and hbsab reactive for a period of time aswell, but I waited and kept taking the viread daily until dr. told me to stop about 1 years later just to make sure hbsag wouldn't come back. the changes I am experiencing is now my digest system is working better, bitter taste in tongue gone, food taste better.
I wish you best luck and hope you can get rid of this virus as soon as possible.
I wish you best luck and hope you can get rid of this virus as soon as possible.
please explain is this anti hbs mean something or not mean my doctor told that he will stop tenefovir after it get positive please explain about it
My dr took me off viread about 1 year after my hbsag non-reactive, and hbsab reactive, hbv dna undetectable. also patient who is take viread might have strong flare after stopping the medication.
This is my opinion:
When she was HBsAg positive, her surface antibody was not the matching antibody to her surface antigen, rather it was to another serotype of the surface antigen (explanation as to why varies from co-infection to mutation).
Finally, she lost her HBsAg, with or without appearance of the matching antibody.
In the theory of antigen-antibody, matching antigen/antibody neutralize each other. Since we are not yet able to detect HBsAg/HBsAb immunocomplex, it may be more appropriate to say when HBSsAg is positive, there is zero HBsAb or an excess of HBsAg over HBsAB. When HBsAb is positive, there is zero HBsAg or an excess of HBsAb over HBsAg.
When she was HBsAg positive, her surface antibody was not the matching antibody to her surface antigen, rather it was to another serotype of the surface antigen (explanation as to why varies from co-infection to mutation).
Finally, she lost her HBsAg, with or without appearance of the matching antibody.
In the theory of antigen-antibody, matching antigen/antibody neutralize each other. Since we are not yet able to detect HBsAg/HBsAb immunocomplex, it may be more appropriate to say when HBSsAg is positive, there is zero HBsAb or an excess of HBsAg over HBsAB. When HBsAb is positive, there is zero HBsAg or an excess of HBsAb over HBsAg.
I know a woman who have been inactive carrier for a long time and she had both HBsAg and HBsAb (low but postitive) for many years but finally she'd lost HBsAg without any treatment. Doest it mean HBsAg and Ab started to match finally ?
If HbsAg is still positive when HBsAb is positive, it means the HBsAb is not the matching antibody for the antigen. Both HBsAg and HBsAb positive at the same time are not uncommon.
In general, HBsAb positive WITH HBsAg positive too is not significant.
2 Comments
means doctor told that he will stop medicine after it get positive
what do you mean please explain ? is it not good to have anti hbs positive what does it mean please help me as you know that i have f4 please explain?
This is my opinion: probably you have f1 to f4 because your immune system who cleared the virus, liver got some damage . But, if you are clear of virus now your liver should regenerate itself, helped by you with correct diet, vit D, exercises.etc. correct me if i am wrong. Best luck!
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