nucs peg add on combo with 100% response and 91% hbsag loss

[stef2011]

this was posted already but it is better to enhance this data for all members and for all readers and keep this thread up all the time and separated

baseline hbsag<1000iu/ml has 100% response and 91% hbsag loss

http://medicalxpress.com/news/2014-04-optimal-combination-therapy-chronic-hepatitis.html

[mer971]

Me, you and Steff are not scientists, nor researchers. This is said because of study done by researchers.

Professor Cihan Yurdaydin from the Department of Gastroenterology, University of Ankara, Turkey, have conducted this study and had presented on liver conference 2014
192 patients who had received at least two years treatment with NUCs without achieving HBeAg loss or seroconversion were treated with 48-week combination therapy with additional Peg-IFN to on-going NUCs or NUCs monotherapy.

Out of this population, 83 patients were treated with combination therapy and 109 patients were treated with NUCs monotherapy. All patients were followed for a further 24 weeks and the HBsAg level was measured both during treatment and post-treatment.
http://virtualpressoffice.easl.eu/three-new-studies-help-clarify-optimal-use-of-combination-therapy-in-chronic-hepatitis-b-patients/

Where is your prof that mostly do not reduce hbsag on nucs? I think that Steff is not misleading anybody, but thanks to him we know much more about hep B. Personally I would thank him,for taking his time to response to everybody,advising them for what he has done through his experience,bringing latest news from pisa's researchers and what is reading from internet. If you have prof for your saying you are very welcome as well.

[melcul]

I am in no position to speak about the treatment of hepatitis but have in mind that at least in my country until last year they treated hepatitis b just to achieve undetectable  hbvdna, they just started to watch hbsag quant .if nucs can lower hbsag, in a few years it is logic that this can be possible after many years to achieve seroconversion. I didnt seen official trials on this but speaking of this, stef, do you have some links on this ? Let's hope that replicor  will manage to get to the market their arc vaccine in the next years

[hatehep]

In patients with baseline HBsAg< 1000 IU/ml, 100% patients achieved complete response and 91% patients achieved HBsAg loss

IN THOSE PATIENTS

how many had hbsag less than 1000? what was hbsag before starting nucs?

what is your hbsag level? how long have you been on nucs?

[hatehep]

nucs do not reduce hbsag in the majoritory and many people are above 1000 iu/ml so how can this work?

if nucs could reduce hbsag so much then why the peg add on?

POST YOUR RESULTS FOR PROOF UNTIL THEN STOP SPAMMING

chronic hep b is currently uncurable, sorry folks.

some people may be lucky and clear on peg/nucs but most will not.

[hatehep]

ok great lets all take nucs for 10 years and hope our hbsag level is below 1000iu/ml then hope peg can clear our hbsag..... great stef2011....   tell me if this is so great then why have you not put it into use? post your results of this cure you speak of and we can all believe........

this is spam...... if this worked we would all be on it.....

false hope.............. stef2011 also posted alinia was the cure....... did that work for anybody? cure to make hbsag positive to negative was your words..... stop misleading people with your theories

[stef2011]

t cell recovery and possible clearance by immune therapies is all thanks to nucs use for 5 to 10 years.so use of nucs is the base of hbv cure