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Avatar universal

thymosin alpha1

any study on this immune modulator reporting hbsag quantitative?also clinical case reports....anyway i am afraid we ll have to trial this ourselves

it would be very helpful to see what it can do on hbsag less than 1000iu/ml, even little is ok since it has low sides effects.
2 Responses
Avatar universal
sciclone makes zadaxin and approved in some asian countries (china for sure) and italy

it is expensive and we dont know if it has any effect on hbsag quant, the trials show hbvdna and hbeag seroconversion, combo with peg, there should be a trial combo with etv but dont know if started/where.no sides effects from zadaxin

with your low hbsag  we know pegintf has a high cure rate

also note that cuban vaccine will be on the market in cuba on march
Avatar universal

found the studies but they require cirrhosis but anyway zadaxin is already on the market so those who can afford it can try theirselves if it lowers hbsag

Optimized Treatment and Regression of HBV-Induced Compensated Liver Cirrhosis – China  
Patients with HBV induced compensated liver cirrhosis will participate in a study to evaluate entecavir alone, entecavir + thymosin-alpha, for varying durations, etc. Assessed at baseline and every 6 months. Contact: Dr. Hong You at 8610-63139019 or ***@**** or Dr. Jidong Jia at 8610-63139816, ***@****.  Refer to identifier - NCT01943617 (Study ID # 2013ZX10002004-3)

Optimized Treatment and Regression of HBV-Induced Early Cirrhosis – China Patients with chronic HBV histologically confirmed with early cirrhosis are randomized in a 1:1 ratio, multi-armed study – entecavir alone, entecavir + thymosin-alpha for varying durations, etc. Assessed at baseline and every 6 months. Contact: Dr. Hong You at 8610-63139019 or ***@**** or Dr. Jidong Jia at 8610-63139816, ***@****.  Refer to identifier - NCT01938820 (Study ID # 2013ZX10002004-2)
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