You need to get in contact with Frank J Perotta --- methinks that you may be having the same issues he is having...
He may have some more info for you than any of us.
He's here on the board - try looking him up.
I will try an find him. Thanks for help.
2 things come to mind, besides the obvious anemia, one is your ammonia level. Get it checked. You need 3 BM's a day and low protein diet whenever you have liver disease. If your liver is not 100 % better, which many never are even with SVR, it means diligence on the diet front. Too much ammonia will make you disoriented and tired.
Two: more patients with HCV have low functioning pituitary. the disease seems to effect this gland, although old age, whiplash, and other things can as well.
Get your doc to do a simple blood test called an IGF-1. (insulin growth factor one).
this will tell if you are making enough hormone to repair your body each night. If you aren't you will feel 90 years old, and spend way more time prone because you aren't repairing tissue.
let me know if this number is low. It is age based. If you are 50 your number should be between 120 and 180. (mine was 40).
you can read more about this on a thread I staarted, I'll find the link.
My guess? Low Thyroid. Obviously I'm not a doctor so this is only a guess based on the symptoms you're describing. But the fact that you wrote a post that includes all your symptoms can be an advantage. When you go see a doctor, you usually see him for individual complaints, so sometimes he's unable to see the whole picture.
And believe it or not, every single symptom you mention on your post is a symptom of LOW THYROID.
Iron deficiency ANEMIA
Mental and physical slowness
Low sex drive
Weakness (and poor circulation)
Slow and staggering movements
See what I mean? Every single one of your symptoms is on the list. And low thyroid can also cause LOW BLOOD PRESSURE, which can cause dizziness when you first get up from being horizontal. So it makes sense when you say.....
"This affect is so severe that if I try to get up from horizontal position that I stumble around as if I have been drinking alcohol"
Also...low thyroid can cause difficulty sweating and perspiration may be decreased or absent even during heavy exercise and hot weather. So that (plus low blood pressure) would impact the ability to exercise.
So it all fits. I have a feeling I'm right.
Plus, I've seen this happen to other people in the past. At first I couldn't believe how something as simple as low thyroid could cause so many severe symptoms and debilitate a person so much. But I also saw those same people recuperate in a few weeks after they got thyroid medication and their levels came back to normal.
I would copy the list of symptoms and talk to your doctor about it. Have him do a THYROID PANEL which includes T3, T4, etc (not just a TSH test).
And come back and let us know what happens!
Good luck to you.
This is the link where I got the info on low thyroid symptoms:
If after first looking into the above useful advice Ammonia and Thyroid, you still don't have an answer consider this:
From Book: Drug-Induced Liver Disease By Neil Kaplowitz, Laurie D. DeLeve
Interferon-alpha inhibits the transcription of mitochondrial DNA into mitochondrial transcripts, thus decreasing mtDNA-encoded respiratory chain polypeptides and mitochondrial respiration. Some of the adverse effects of Interferon-alpha, such as minor blood dyscrasias, myalgias, paresthesias, convulsions, and depression, resemble those observed in mild forms of inborn mitochondrial cytopathies.