Hi All, I completed a 12 week trial with sofosbuvir + GS 5816 five weeks ago. Trial is blind however I did get my liver function test results all the way through, both by ALT & AST dropped into the normal range and have stayed there - ALT dropped very quickly, AST was slower to decrease. At the end of the trial ALT was 25, AST around 30 - I've seen much lower numbers posted by people but I do have cirrhosis. 4 weeks after finishing the trial my ALT & AST were more or less exactly what they were on the final day of the trial, I think both were up 2 points, to 27 & 32.
My question is this; How quickly would ALT & AST rise if TX had not been successful? Both were around the high nineties, one hundred level before TX. A PCR test is $450 and while I'm busting to find out if I have achieved SVR I'm thinking my ALT & AST are a good guide. Am i wrong?