Here is a curveball, along with an article regarding the highprevalance of HCV in alcoholics. See link below.
This is an issue that I have discussed with several HCV doctors, with no clear answer to my questions. The article, as well as several others I have reviewed lately, indicates the abnormally high number of heavy drinkers, alcoholics, etc. that are HCV positive. Often this is within populations with no known risk factors, and no past IVDU history. My big question, which I have wondered about for years, is WHY does this seem to be the case. Why would heavy alcohol users seem prone to developing HCV??? Unless, of course, they are all lying, and happen to also have risk factors which they now deny. I think there is much more to this mystery, which still baffles the medical community.
Along with my concerns about persistent HCV after SVR, is another concern which many of you have responded to in the past when I have posed this issue. Could there be HCV transmission in the general population, on a much larger scale than suspected, that is not in the bloodstream or liver. In effect, a 'latent' tissue, or glandular infection which remains latent or suppressed, until a major stimulus causes it to 'explode' into the bloodstream. This theory would help explain the great numbers of HCV cases worldwide that have no known risk factors.
Could there be a somewhat 'dormant' viral infection in a large portion of our population, within organs like salivary system, sexual organs , membranes, CNS, etc.??? (cont. below)