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Am I the only one all hyped up on grapefruit?
I read the article from Science Daily Feb. 08 and the articles on Hepatitis Central, Liver Foundation and Hepatitis Foundation International. They seem real positive about grapefruit. They also list a few drugs which can't be taken with grapefruit. Just came back from my doctor and he said I could have it. He says he has grapefruit everyday. Well, I had already started eating and drinking it. Thought I would be the guinea pig! Maybe I should change my name to the Grape Fruit! Going to be shot 17 tomorrow and feel good today! UND at 12 week and doc says I have a 60-65% chance of clearing. Thanks to all of you for helping to keep me positive. So, see what you think about grapefruit!!
DelMonte Fruit Naturals come in a box. These are red grapefruit cups that are delicious and don't make you pucker as slicing into a defenseless grapefruit does. They are available at Costco and grocery stores.
I also drink one small glass daily of pure pomogranate juice by Lander's, also available at Costco and other stores. The combination of these two has helped bring down the viral load according to my last blood work. The Hepatologist and Gastroenterologist both know I have this daily regiment and did not warn me about any adverse effects or potential trauma to my body or liver....Otherwise, it's up to you...
Magnum
I also drink one small glass daily of pure pomogranate juice by Lander's, also available at Costco and other stores. The combination of these two has helped bring down the viral load according to my last blood work. The Hepatologist and Gastroenterologist both know I have this daily regiment and did not warn me about any adverse effects or potential trauma to my body or liver....Otherwise, it's up to you...
Magnum
Everything I have found, agrees with Cocksparrow's information. We have purchased naringenin capsules very affordably from Swansons vitamins on the web. Just check and double check your other meds with a pharmacist before taking it. I bothered several pharmacists before I was satisfied that we were ok. HR recommended taking other good antioxidants if you were trying naringenin to help counterbalance the oxidation possibility. He didn't advise using it. He just laid out cautions if you decided to use it.
We have chosen to take some calculated risks with this being Joe's 3rd attempt and him being at stage 4.
Go with caution,
Ev
We have chosen to take some calculated risks with this being Joe's 3rd attempt and him being at stage 4.
Go with caution,
Ev
Maybe this is a repeat..if so..apologies.
You might want to consider taking citrus bioflavonoids which contains naringenin.
Haven't found that flavanoid alone so far.
Like said in the article...it would probably need to be taken by injection for it to be very affective.
Aren't there more sensitive tests?...5 IU/ml?
Grapefruit Compound Inhibits Hepatitis C Virus
Flavonoid called naringenin silences infection pathway, hints of new disease treatments
-- Robert Preidt
TUESDAY, May 6 (HealthDay News) -- The grapefruit flavonoid naringenin inhibits the secretion of Hepatitis C virus (HCV) in infected cells and could offer a new approach for treating the disease, according to a Harvard Medical School study.
About 3 percent of the global population is infected with HCV, which can lead to cirrhosis and liver cancer. The current standard therapy of interferon and ribavirin is only effective in about 50 percent of cases and can cause major side effects, according to background information in the study.
Recent research suggests that HVC may be "hitching a ride" along the lipoprotein life cycle, and that compounds and dietary supplements that influence lipoprotein metabolism may also affect HCV.
In this new study, researchers demonstrated that HCV is actively secreted by infected cells while bound to a very low-density lipoprotein.
"Silencing apolipoprotein B (Apo-B) mRNA in infected cells causes a 70 percent reduction in the secretion of both ApoB-100 and HCV. This ApoB-dependent HCV secretion pathway suggests a novel therapeutic approach for the treatment of HCV infection," the researchers wrote.
They then tested the grapefruit flavonoid naringenin and found it reduced HCV secretion in infected cells by 80 percent.
"The concept of supplementing HCV patients' diets with naringenin is appealing," the researchers wrote.
*But they noted the intestinal wall doesn't absorb naringenin well, which means therapeutic doses of the flavonoid would have to be given by injection or combined with other compounds to boost its absorption by the intestines.
The researchers also noted that naringenin and several other compounds in grapefruit have significant drug-drug interactions.
"Future studies would focus on long-term ability of naringenin and perhaps other citrus flavonoids to reduce viral load in animal models and long-term cultures of primary human hepatocytes," the researchers concluded.
The study was published in the May issue of Hepatology.
More information
The U.S. Centers for Disease Control and Prevention has more about hepatitis C.
content by:
SOURCE: Hepatology, news release, April 29, 2008
You might want to consider taking citrus bioflavonoids which contains naringenin.
Haven't found that flavanoid alone so far.
Like said in the article...it would probably need to be taken by injection for it to be very affective.
Aren't there more sensitive tests?...5 IU/ml?
Grapefruit Compound Inhibits Hepatitis C Virus
Flavonoid called naringenin silences infection pathway, hints of new disease treatments
-- Robert Preidt
TUESDAY, May 6 (HealthDay News) -- The grapefruit flavonoid naringenin inhibits the secretion of Hepatitis C virus (HCV) in infected cells and could offer a new approach for treating the disease, according to a Harvard Medical School study.
About 3 percent of the global population is infected with HCV, which can lead to cirrhosis and liver cancer. The current standard therapy of interferon and ribavirin is only effective in about 50 percent of cases and can cause major side effects, according to background information in the study.
Recent research suggests that HVC may be "hitching a ride" along the lipoprotein life cycle, and that compounds and dietary supplements that influence lipoprotein metabolism may also affect HCV.
In this new study, researchers demonstrated that HCV is actively secreted by infected cells while bound to a very low-density lipoprotein.
"Silencing apolipoprotein B (Apo-B) mRNA in infected cells causes a 70 percent reduction in the secretion of both ApoB-100 and HCV. This ApoB-dependent HCV secretion pathway suggests a novel therapeutic approach for the treatment of HCV infection," the researchers wrote.
They then tested the grapefruit flavonoid naringenin and found it reduced HCV secretion in infected cells by 80 percent.
"The concept of supplementing HCV patients' diets with naringenin is appealing," the researchers wrote.
*But they noted the intestinal wall doesn't absorb naringenin well, which means therapeutic doses of the flavonoid would have to be given by injection or combined with other compounds to boost its absorption by the intestines.
The researchers also noted that naringenin and several other compounds in grapefruit have significant drug-drug interactions.
"Future studies would focus on long-term ability of naringenin and perhaps other citrus flavonoids to reduce viral load in animal models and long-term cultures of primary human hepatocytes," the researchers concluded.
The study was published in the May issue of Hepatology.
More information
The U.S. Centers for Disease Control and Prevention has more about hepatitis C.
content by:
SOURCE: Hepatology, news release, April 29, 2008
The sensitivity is 50 IU/ml
Correct, even though UND, the virus is still in hiding and thus you need to treat for 48 weeks.
Marcia
Correct, even though UND, the virus is still in hiding and thus you need to treat for 48 weeks.
Marcia
Yes, I cleared at 12 week, test just said <50. From Quest Lab. Not sure how sensitive. But I am going 48 weeks. The virus is still hiding in the tissues, correct. I think thats what I was told.
Cindy
Cindy
I started buying grapefruit juice after reading things on this forum. I put a little steviaside in it to sweeten it up(another "might be beneficial" substance). Not on treatment, not holding my breath waiting for grapefruit. I think grapefruit also has something to help the memory. Now what was this thread about? . . . . .
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