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Brown Urine

Side Effect of Hepatitis C Treatment - Brown-colored Urine?  Should I be concerned?
21 Responses
408795 tn?1324935675
Your pee should be fairly clear if you're drinking as much water as you should be.  The rule of thumb for how much water says to take your weight in pounds, divide that in half and that's how many ounces of water you'll need each day.  Usually it equals a little more than a gallon.  Of course if you're big it's gonna be a couple of gallons or more.  Either way, drink enough water and on top of that drink more.  If you're concerned see your doctor.  good luck with the rest of your journey
577132 tn?1314266526
They only time I experienced very dark urine while on treatment was when I hadn't consumed enough water, as fret as outlined above.  

On one of those occasions I had to do an MSU for my monthly safety test and the colour of my urine (very dark) raised a flag.  It was noted on the report as excessive Urobilinogen and my urine was tested for the presence of white blood cells which came back as normal.  I really think it was dehydration that caused it.

There are other reasons for the dark or discloured urine, here is a useful link for you:


Perhaps you could increase your water intake as per the guidlines fret has mentioned and if the colour still persists then ask your doctor for a urinology test.  I would hope they are being done regularly as part of your care as it's important to also keep an eye on kidney functions whilst treating.
Avatar universal
It's it's brown as opposed to dark yellow, could be blood in urine. from urinary infections, etc, See your doctor and get your urine analyzed for a proper diagnosis.

-- Jim
Avatar universal
You should not being peeing brown urine. They can easily test a sample for bilirubin which should NOT be in the urine. Brown urine is a sign of jaundice, so see your doctor ASAP.
717272 tn?1277590780
See your doctor and drink enough water before you go to be able to produce a sample for urinalysis.  That will quicly show if there is blood or concentrated bilirubin in urine.  Brown urine is not normal.
547836 tn?1302832832
are you currently on any other medication?  urine is generally yellow when you don't drink enough water or take vitamins regularly, but when i started on beta-blocker for my heart and methimazole for the thyroid, i started to get some yellow, i guess body adjusted to it, it stablized..
Avatar universal
Brown urine could mean trouble, if it is truly brown colored. It could be a sign of dehydration, yes but could also mean kidney failure. Call your doctor ASAP.  
Avatar universal
My pee was brown at the beginnning of my TX too....im fine...i think it was just the TX drugs doing strange things...it wasnt red,,,,justa shade brown...
475300 tn?1312423126
Mine was brown right before I treated.  One of my doctors told me it was my liver "acting up".  My dermatologist told me it was a part of the whole Porypheria PCT thing.  I wasn't jaundiced either.  

Avatar universal
Mine was brown right before I treated.  One of my doctors told me it was my liver "acting up".  My dermatologist told me it was a part of the whole Porypheria PCT thing.  I wasn't jaundiced either.  
Was this based on a urinalysis or just docs guessing? My urine was brown right before I treated and it was trace blood due to a urinary tract infection confirmed by a simple urine dip stick.
Avatar universal
I was thinkn it was maybe the virus being excreted by the kidneys.
475300 tn?1312423126

13). In porphyria cutanea tarda, the urine will appear reddish brown in natural light but fluoresces pink under ultraviolet light (17).
Avatar universal
From Mayo Clinic:

Dark brown or tea-colored urine

Food. Eating large amounts of fava beans, rhubarb or aloe can cause dark brown urine.
Medications. A number of drugs can darken urine, including the antimalaria drugs chloroquine and primaquine; the antibiotic metronidazole; nitrofurantoin, which treats urinary tract infections; laxatives containing cascara or senna; and methocarbamol, a muscle relaxant.
Medical conditions. Some liver disorders, especially hepatitis and cirrhosis, and the rare hereditary disease tyrosinemia can turn urine dark brown. So can acute glomerulonephritis, a kidney disease that interferes with the kidney's ability to remove excess fluid and waste. The stools may turn gray or whitish also.

Your skin/mucous membranes do not have to be yellow to be jaundiced. It depends on how much bilirubin is being put out. Dark urine is the first sign of jaundice. Do not ignore this.
475300 tn?1312423126
Jenny, I absolutely understand  that I am not the most knowledgable but I can not find where jaundice does not necessarily cause yellowing of the skin and whites of the eyes.  I  agree that it should be looked into by a doctor & hopefully the original poster willbring this to the attention of his doctor.   In my case it was due to hepatitis and porphyria PCT so obviously the liver was not functioning properly.


If a fever or flu-like illness comes before jaundice, it's usually a sign of a viral hepatitis infection. Brown urine, common in hepatitis, is generally a sign of poor liver function or increased red blood cell destruction. The body is trying to get rid of excess bilirubin in the urine. Pale, white, or clay-coloured stool, on the other hand, is an indicator of obstruction in the gallbladder or bile ducts. Many people with obstruction due to gallstones experience abdominal pain, while those with obstruction due to tumours usually have painless jaundice.

Jaundice itself is unlikely to hurt you unless the bilirubin reaches very high concentrations. It is a sign, however, of an underlying problem. There are too many possible causes of jaundice to attempt diagnosis at home. You should see a doctor if you think you have jaundice.

184420 tn?1326739808
my dr told me dark urine and black stools are signs of cirrosis...

my urine is usually very light as i drink alot of water... if i dont go for a while is more yelow  ... and bright yellow after my super b complex vitamin...

i am constantly examining my urine & stool (yes gross i know haha) ... im not treating right now im waiting for the PI's stage 2/grade 2 hoping it stays that way for at least the next few years...
Avatar universal
LOL. well, given all of our online diagnosis, "Gibby" is probably paralyzed with fear by now been unable to dial "911" :)

But seriously, Brown urine has MANY causes. Some serious and some quite benign. Obviously the right thing is for him to simply see his Dr. and get tested.

-- Jim
475300 tn?1312423126
HaHaHa........That was exactly my point, many causes and in My case it went away with TX and hasn't come back thank goodness

Avatar universal
I am saying that you don't have to look jaundiced to be considered jaundiced from personal experience. Last summer I was hospitalized with neutropenia and my urine was like coca cola. My bilirubin was 2.7. My hep doc explained to me that medically I was jaundiced as he could tell from my urine and bili levels but they need to be a bit higher than 2.7 to see the yellowing in the mucous membranes. They turn yellow and the skin follows as the bilirubin levels go higher. With me, it was unrelated to hepatitis/cirrhosis. And the levels were down to less than 1.0 within 2 days.
Avatar universal
Couldn't Gibby be jaundiced (dark urine) from hemolytic anemia from the ribavirin?
475300 tn?1312423126
Thanks for the explaination
Avatar universal
I had Hep C went through P/Interferon 6mts of pure misery, then nearly died of Pericarditas/Pleurisy, had surgery, was extremely anemic, all my muscles completly shot, and now I'm having female & urinary problems of having to go all the time, but can't.  Now the urine is brown.  

The only good thing out of all this is, so far I'm negative for Hep C and holding.

I'm thinking about seeing a urologist this coming week as we don't have a Hep doctor in this area (Southern Oregon), and I'll never go back to the doctor that dumped me after the treatment process was over, said it wasn't his field.  Gota love em, NOT.....

So bummed, is this whole thing gonna kill me?  The doctor said I had fibrosis, but if I didn't drink (which I don't) I would be ok.  Well I've been everything but ok since I began the treatment, (I was fine before).
Bummed out!!!
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