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18227105 tn?1463522012

Can you tell me what hep c genotype i have?

go to my profile and check on my photos and see my last PCR and tell me about it and if harvoni good for it or what? what genotype is?
8 Responses
Avatar universal
Unless I'm missing something, the report does not seem to indicate which genotype you have.   However, I found this in a medical journal:

"Hepatitis C virus genotype 4 (HCV-4) is the most common variant of the hepatitis C virus (HCV) in the Middle East and Africa, particularly Egypt. This region has the highest prevelance of HCV worldwide, with more than 90% of infections due to genotype 4."

So, since you are from Egypt, you probably have genotype 4.  And according to reports, Harvoni is very effective against genotype 4.   I'm not a medical professional, so you really should discuss this with a doctor, preferably a liver specialist.
18227105 tn?1463522012
Yes im from Egypt and most of people have genotype 4 but what test i should make to be sure. and my pcr can tells the liver case or not? thanks so much
683231 tn?1467323017
You need a different test for genotype.

The HCV RNA by PCR only shows viral load or "not detected"
18227105 tn?1463522012
what test i need?
683231 tn?1467323017
Hep c genotype test
18227105 tn?1463522012
we dont have it here. it needs a lot of money and 45 days to go to germany and come back and i will buy Harvoni in 10 days
683231 tn?1467323017
Harvoni is only approved for Genotypes 1,4,5 or 6

If you have genotypes 2 or 3 Harvoni is not as effective.

Genotype 2 Treatment-naïve Patients without Cirrhosis - Recommended regimens.


Daily sofosbuvir (400 mg) and weight-based Ribavirin for 12 weeks is a Recommended regimen for treatment-naïve patients with HCV genotype 2 infection who do not have cirrhosis.
    
Daily daclatasvir (60 mg*) plus sofosbuvir (400 mg) for 12 weeks is a Recommended regimen for treatment-naïve patients with HCV genotype 2 infection who do not have cirrhosis and who are not eligible to receive Ribavirin.

Genotype 3 Treatment-naïve Patients without Cirrhosis - Recommended regimens.


Daily daclatasvir (60 mg*) plus sofosbuvir (400 mg) for 12 weeks is a Recommended regimen for treatment-naïve patients with HCV genotype 3 infection who do not have cirrhosis.
    
    Daily sofosbuvir (400 mg) and weight-based RBV plus weekly PEG-IFN for 12 weeks is a Recommended regimen for treatment-naïve patients with HCV genotype 3 infection who do not have cirrhosis and who are eligible to receive PEG-IFN.
683231 tn?1467323017
Your doctor said they don't have the test in Egypt? I would ask a different doctor about that maybe one associated with a University Hepatology department.

I did find that genotype 4 is the dominant HCV genotype in Egypt

I also found this about Genotype testing in Egypt

In response to this rapidly spreading virus, an American University in Cairo (AUC) research team at the Yousef Jameel Science and Technology Research Center, led by Hassan Azzazy, professor of chemistry, has designed a novel test capable of detecting all genotypes of HCV in less than one hour, instead of days, and at one-tenth of the cost of traditional tests.

“Our test is sensitive and inexpensive, and it does not need sophisticated equipment,” explained Azzazy, adding that detecting HCV during the first six months raises the recovery rate to 90 percent. “Little is done on the national level to combat the alarming prevalence of hepatitis C in Egypt.”
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