I don't wish to sound like a ninny -- for I am beyond lucky... But a trial is exactly that... A trial.
They do NOT know what is going to happen.
Anything - including death can happen at a trial.
I do not believe in trials for me.
I do not think I would be in the first groups of humans to test out a product --- I'm sorry. I just don't have that much faith in human science... YET...
There will be a time in the future - that humans will understand how we are exactly created - and what substances will do... They will understand the chemical components and they will be able to see more clearly what future results will be.
Until that day - however - trials are shots in the dark.
No one knows what will happen ---- for good or for bad... and how far in the future.
When you do a trial - you should know that.
You might cure --- you might die --- you might never be able to cure --- you might become INF resistant - you might cure half way then get another disease.... and so on ad infinitum.
I'm glad you are warning others - but you should not be so angry for yourself.
Keep your chin up --- and your hopes out...
There will someday be a cure.
I was at Hep Dr. on Wed., I barely read about the conference before the appt. What I did ask was would I be considered interferon resistant?...He said NO...I am a slow responder. BTW, he was at AASLD. I don't know if he was playing golf, or downing shots at the bar..but. I am 35 weeks (or so) double dosing 2x a week...my last pcr showed a vl 1350...down from 45000 4 wks. b4. He gave the impression I should be happy....I asked about Alinia...he said maybe down the road..if necessary. So here i am double dosing...weight based should be taking 1000 mg. riba but an overdosing with 1400 mg.....and feelin' some rage today.
I feel like I'm between a rock and a hard place. I have just about had mor3e than I can take today...i can't seem to find a point for anything. Woe is me.
No disrespect to anyone, but I don't think things are necessarily as black and white as presented and the idea that you may have f*cked up future chances may not be correct. Please take your concerns to your doctor or another specialist and have them review your history against what is coming out of AASLD, including the resistance issue. I would think that if the repercussions of failed triple tx were that bad we'd be hearing more. At least don't give up hope without exploring things further.
would you mind giving me the address of the thread -- I can't find it
Did you say you've been double dosing for 35 weeks and you still have viral load of 1350?
Have you gotten another opinion on your treatment? I forgot your stats, but I believe most stop at week 24 if still detectible unless you're treating only to improve liver condition as opposed to having reasonable odds of SVR. Also, never heard of anyone double dosing that long.
No...I started DD at 26 weeks..@ 10 -11 weeks upped riba from 1000 to 1400mg. I Have asked to stop tx....Hep Dr. (Director of Hep. Dept at a University Hosp) says...he cannot advise that at this time....
Be gentle with me fellows...I'm having a very rough day.
My thoughts are with you. I can see you are having a difficult time.
Trials are trials, yes, but the arms without ribavirin seemed to be a lost cause from start. I understand dointime's reaction. One would think it is not too much to ask to have the risk of resistance explained ahead of entering a trial.
Dr D told me that one of the PIs in trial, I think the one from BI, goes after a different sequence in the RNA and would be effective with people resistant to Telaprevir.