Thaks for posting that news. It sounds very promising and will give people who fail triple med treatment some hope of cure
As with many of us, I am still on treatment and I do have a concern about relapsing after finishing treatment. Therefore, any news about successful new treatments is very good news for me and for all of us.
I put this together and posted to another forum where people are a lot less knowledgeable about trials but thought I'd post here as well.
This is what I understand from the info released this morning.
7977 + Ribavirin, 12 weeks, gt 1, SVR4 88%
7977 + BMS 790052 (daclatasvir) 24 weeks, gt 1, SVR4 100%
7977 + BMS 790052 (daclatasvir) 24 weeks, gt 2/ 3, SVR4 91%
7977 + Peg IFN + Riba 12 weeks, gt 1, SVR12 90%
7977 + Ribavirin, gt 1SVR4, 59% - (Quantum study) only 16% had the ILB28 CC on this.
So,interestingly, the IL28B seems to be strong indicator of SVR. My understanding was that it was thought to have been a response to interferon. It doesn't seem like that anymore.
Just read the news myself! As Pooh said, as a current treater the thought of failing triple therapy is there ...this gives me much relief!! My family has yet to be tested (I know their chances of having it are low) but if I do get hit with some unexpected news the results above make me feel much better. I would never want my husband or son on peg/riba/Inc for 24-48 weeks if there is something like this coming out within the next 5 years.
These are all great results and the future certainly looks bright ,however keep in mind these are all results on "naives " from what I can tell.
I am just praying this is the only time I will have to do this. Being one of the hardest things I have ever endured in my life, I think of finishing treatment as one of my greatest accomplishments in my life. (To achieve SVR would be one GIANT. cherry on top.) I have hope my triple will work..;) the news above makes me SO happy for all the treaters to come.
Did anyone see the Street mention that Gilead and Bristol can't seem to work together and that may keep this combo from going any further? How disappointing!!
I had not heard that ,however something tells me that ,like all "pharma's", their insatiable appetite for profit will keep things moving in the right direction.
Best to you..
Having friends with hep C and so far, minimal liver damage, I am excited about the new orals. I believe they will be the treatment of the future.
Of course, those of us who've done tx, do not want to go down this road again. For those who do relapse, there is now hope for an easier treatment option.
Story about the two pharma's not wanting to work together :-( That will put a damper on future clinical trials. Dang pharmas!