@OC, Since Sofosbuvir is fast tracked by the FDA, it will be approved or rejected in 6 months.
@JimmyMose, yes they need to combine Sofosuvir with another DAA to increase effectiveness. Currently, they're combining it with Ledipasvir, a NS5A inhibitor, with quite good results...
More Sofosbuvir news Early 2Q Done
Gilead Submits New Drug Application to U.S. FDA for Sofosbuvir for the Treatment of Hepatitis C 4-8-2013
http://www.gilead.com/news/press-releases/2013/4/gilead-submits-new-drug-application-to-us-fda-for-sofosbuvir-for-the-treatment-of-hepatitis-c
HCV Treatment — No More Room for Interferonologists?
http://www.nejm.org/doi/full/10.1056/NEJMe1303818
What are we to conclude from these studies? The low incidence of side effects, the relatively short duration of treatment, and the pangenotypic properties of the drugs are strong selling points of a sofosbuvir–ribavirin regimen and will probably lower the threshold for HCV treatment for both patients and physicians. The likely next step is to combine sofosbuvir with other direct-acting antivirals to enhance its potency. Is the interferonologist down and out? I do not think so, but it is surely time for reeducation.
This is hopeful but past experience tells us to be cautious.
Nobody knows how long it will actually take the FDA to approve anything.
how many weeks were you taking the meds?
How were you able to get into a trial? Were you treatment naive? Or had you previously failed a treatment with Peg-Ifn? I can't get into a trial because I don't fall into either category. Had prior treatment with just plain interferon and ribavirin. Arghhhh.
No..it was with INF and Riba..
Did you have it with Riba & Ledispavir?
That is very good news!!
I'm GT 1a and the Sofosbuvir w/ the triple therapy just Cured me..SVR
~Country
Such good news! This has made my day :-). Thank u for this post!