Aa
Experiencing Alcohol and RX Drug Reactions since TX
My background = HVC Geno-2a, TXd'24 weeks once. Relapsed and will TX again for 48 weeks soon.
The point of this post is incase anyone here has experience the same they can ID it and act. It may not have anything to do with HVC or TX but.........?
Pre TX the only RX I was allergic to was Viox causing raised red skin welts looking like poison oak but without the itch.
The reason for the Viox treatment was CPPD, Calcium Pyrophosphate Dihydrate Crystal Deposition (CAL-see-um PIE-row-FOX-fate DIE-high-drate DEH-poo-ZISH-un) is a condition that causes pain, redness, heat, and swelling in one or more joints. Also referred to as Pseudo Gout or Chondrocalcinosis. It is not diet driven like Gout.
Pre TX I could drink beer as I wanted to without pain. Even with the CPPD lurking, it would not activate it.
Post TX just ONE beer turns it on pretty bad and takes about two weeks to go away. I can still work without taking meds for it. No more beer forever.
The worst I ever had it was the first flare up and it took Dr's a long time to diagnose. Double doses of Celebrex, Cortisone shots, three knee drains, multiple blood works, and six weeks out of work later it was found out and over. Not cured but under control.
Now, after TX I have had two lower back muscle strains and was RXd' FLEXERIL to relax the muscles along with an anti-inflammatory. It turns out the Flexeril floors me joint wise to the point I lost two days of work. It took two times to do the math. I could barley dress myself and hobbled to the bathroom. I dropped the flexeril and took the anti-inflammatory and came out of it.
So after TX be prepared for RX drugs to possibly act differently than before. Coincidence?
The point of this post is incase anyone here has experience the same they can ID it and act. It may not have anything to do with HVC or TX but.........?
Pre TX the only RX I was allergic to was Viox causing raised red skin welts looking like poison oak but without the itch.
The reason for the Viox treatment was CPPD, Calcium Pyrophosphate Dihydrate Crystal Deposition (CAL-see-um PIE-row-FOX-fate DIE-high-drate DEH-poo-ZISH-un) is a condition that causes pain, redness, heat, and swelling in one or more joints. Also referred to as Pseudo Gout or Chondrocalcinosis. It is not diet driven like Gout.
Pre TX I could drink beer as I wanted to without pain. Even with the CPPD lurking, it would not activate it.
Post TX just ONE beer turns it on pretty bad and takes about two weeks to go away. I can still work without taking meds for it. No more beer forever.
The worst I ever had it was the first flare up and it took Dr's a long time to diagnose. Double doses of Celebrex, Cortisone shots, three knee drains, multiple blood works, and six weeks out of work later it was found out and over. Not cured but under control.
Now, after TX I have had two lower back muscle strains and was RXd' FLEXERIL to relax the muscles along with an anti-inflammatory. It turns out the Flexeril floors me joint wise to the point I lost two days of work. It took two times to do the math. I could barley dress myself and hobbled to the bathroom. I dropped the flexeril and took the anti-inflammatory and came out of it.
So after TX be prepared for RX drugs to possibly act differently than before. Coincidence?
Interesting history. Sorry about your CPPD. Sounds painful, and I hope they'll find something to help you with that pain that you can take without feeling wiped.
About the beer, I know several who have never treated and say they simply cannot drink a beer anymore, either, because they feel like they've been hit by a truck if they do -- (just one or two will do it to them.) I have also heard that the hep alone can cause you to react differently to drugs, and that would make sense because your liver could be impaired and may not be metabolizing the drug like it should at the recommended dose.
I don't know anything about post-tx (not personally) or how drugs begin to react differently post-tx, but I'm certain they can indeed be very different.
I'll say this much about Flexeril. I had been prescribed Flexeril many times in years passed for acute cervical pain. It worked well for me. I didn't feel great on it, but it didn't wipe my a** totally out, and I could work just fine. Just prior to my diagnosis of Hep C, I had been on another course of it and had been taking it for at least a month. I began to feel like I was dieing. I didn't associate this ill-feeling with Flexeril because I knew Flexeril very well, and it had never flattened me out like that, and so I went to the doc (has just had a CBC done 6 months earlier which was fine). On this CBC, though, my enzymes were up, my platelets, rbcs, and wbcs were down (this is why I was diagnosed - abnormal labs and history of hep in 70s). I stopped the Flexeril because I did not know what this drug might be doing to my liver. My labs (CBCs and liver functions) for at least 10 years previous to diagnosis had been normal every year on annual physical exam.
It could have been the fact that I had had this virus 30 years and was just at the point that symptoms and change in labs was going to occur. What is strange, though, to me is - having been off all Flexeril, all of my labs returned to normal and have been normal since January 2004. I get them done every three months. Also, a recent fibrosure indicated the degree of inflammation and fibrosis has improved since my first biopsy (which was done when my labs were whacky and when I so sick feeling and had been eating all that Flexeril).
In my heart, I swear I think Flexeril was hurting my Hep C liver and was one reason my enzymes shot up and my platelets, rbcs, and wbcs went down. I know I'll never take it again :)
About the beer, I know several who have never treated and say they simply cannot drink a beer anymore, either, because they feel like they've been hit by a truck if they do -- (just one or two will do it to them.) I have also heard that the hep alone can cause you to react differently to drugs, and that would make sense because your liver could be impaired and may not be metabolizing the drug like it should at the recommended dose.
I don't know anything about post-tx (not personally) or how drugs begin to react differently post-tx, but I'm certain they can indeed be very different.
I'll say this much about Flexeril. I had been prescribed Flexeril many times in years passed for acute cervical pain. It worked well for me. I didn't feel great on it, but it didn't wipe my a** totally out, and I could work just fine. Just prior to my diagnosis of Hep C, I had been on another course of it and had been taking it for at least a month. I began to feel like I was dieing. I didn't associate this ill-feeling with Flexeril because I knew Flexeril very well, and it had never flattened me out like that, and so I went to the doc (has just had a CBC done 6 months earlier which was fine). On this CBC, though, my enzymes were up, my platelets, rbcs, and wbcs were down (this is why I was diagnosed - abnormal labs and history of hep in 70s). I stopped the Flexeril because I did not know what this drug might be doing to my liver. My labs (CBCs and liver functions) for at least 10 years previous to diagnosis had been normal every year on annual physical exam.
It could have been the fact that I had had this virus 30 years and was just at the point that symptoms and change in labs was going to occur. What is strange, though, to me is - having been off all Flexeril, all of my labs returned to normal and have been normal since January 2004. I get them done every three months. Also, a recent fibrosure indicated the degree of inflammation and fibrosis has improved since my first biopsy (which was done when my labs were whacky and when I so sick feeling and had been eating all that Flexeril).
In my heart, I swear I think Flexeril was hurting my Hep C liver and was one reason my enzymes shot up and my platelets, rbcs, and wbcs went down. I know I'll never take it again :)
Fibromyalgia? Why?
I have not heard that one. I am a 2-3 liver condition though.
Also my neupogen got low on last TX.
I have not heard that one. I am a 2-3 liver condition though.
Also my neupogen got low on last TX.
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