Gilead Trial with Sofosbuvir & GS-5816

[mdudley]

Gilead Sciences:  Twelve week Phase 2 trial of sofosbuvir + GS-5816 (without ribavirin or interferon) for genotypes 1, 2, and 3 treatment-naïve.

The Protocol Number:  GS-US-342-0102
Clinical Trial Number:  NCT01858766

Anyone else in the Gilead 12-week trial with sofosbuvir & GS-5816 (without ribavirin or interferon)?  The initial enrollment was 140 patients and I would like to connect with or hear from anyone else who may be in these trials.  Thanks!

[theskier]

Your story is really interesting. Let us know when you get the real deal because it for sure will wire you up and grab your stomach from time to time but other than that the war begins and c will lose. I completed treatment Jan 12.There are a lot of strange phases during the war;sleep  fatigue inspite of the wirey drug. I was called this thursday and told I had the real pill. August is next appt. The body aches have diminished  tremendously but the last week liver region is on fire 24/7 very weak. F4 is a bad place to be so eliminating all fun food. No medicine, no marijuana as I recently see that it can contribute to fibrosing.. Hope you are being treated by now  drink lots of water..

[patra_]

Congratulations!!  What a wonderful place to be!!

Now, step up the last step onto the dias and receiver your Dragon Slayer, Supreme Insignia!

Please don't forget to go to the SVR or Relapse threat that Nan535 started, so that there is a record!

Blessings, and enjoy your Hep C FREE life!  : -)

Pat

[jenn1958]

I found out today that I am SVR 12.  I started the Astral 1 trial on November 24th.  I am 57 and have had hep C since I was 17 so I am looking forward to seeing what life is like without the virus.  I have noticed some changes which I had never even associated with hep C.

[caz77777]

and these results from the triple phase 2...http://investors.gilead.com/phoenix.zhtml?c=69964&p=irol-newsArticle&ID=2039076

xox

[caz77777]

Here you go: https://clinicaltrials.gov/ct2/show/NCT02378935?term=hepatitis+c&cond=%22Hepatitis+C+Virus%22&lup_s=03%2F18%2F2015&lup_d=30

[caz77777]

Interesting, thanks for posting...doesn't feel right for me, I did not actually feel better, but wired and tired, and my skin cleared unexpectedly in the first week, and has stayed clear. This was the last thing I had anticipated, and the wired/spaced feeling I hadn't heard about till after I had reported it myself, I simply felt as if I had had too much coffee...Now I know that an active placebo exists I think this is quite likely, since Gilead make both the drug and the placebo. It is neither here not there really, it just made it more of a shock for everyone concerned. I still felt ill after treatment even though I thought I was cured. I am glad now as I have a chance to feel better maybe!