Aa
Aa
A
A
A
Close
Avatar universal

Great Article On Management of Insulin Resistance and Metabolic Syndrome in HCV

Here is the article:

http://www.hivandhepatitis.com/hep_c/news/2007/121206_a.html

This may be helpful to both HCV+ members, and post treatment SVR's.
Doctors are finally beginning to recognize the connection between HCV and Diabetes, Metabolic Syndrome, and related disorders.

DoubleDose
21 Responses
Sort by: Helpful Oldest Newest
96938 tn?1189799858
I know what you mean.  More Power To The Bulls!
Helpful - 0
Avatar universal
Ahh you meant Torero...
I personally dislike those guys and their entourage...I don't like bullfighting at all(it is brutal and arcaic)(at least the Spanish version is, cause in Portuguese and French fiesta they never stab or kill the bull.... and I really appreciate when the bull wins..that's never too often.
Helpful - 0
96938 tn?1189799858
Sorry, my writing was confusing.  The guy was a famous bull fighter and the way people reacted around him (rock star treatment) you would have thought he was a famous hepatologist, not just a normal hero celebrity.
Helpful - 0
Avatar universal
Hi Florida Guy:
They don't have the name of the test as such but maybe you could email them and ask them the equivalent in the US or maybe the manufacturer. "Test de resistencia a la insulina" is the generic name:

http://www.juntadeandalucia.es/servicioandaluzdesalud/hrs/MEDI_WEB/cartera_diferencial.htm

http://www.unilabs.es/catalogo.asp?ID=1&servicio=1

Dr Torredo? never heard of the guy. But my docs are young & extremely friendly & internet savvy. Not like the jerk that dx me. He didn't even wanna shake my hand.

saludos and have a good weekend
Helpful - 0
Avatar universal
After I read the "nil" comment, my gut reaction was to post immediately...who the f...are you to make such a statement.
Still steaming, I decided to read on and saw your answers, knowing that you as a diabetic would get your feathers ruffled.
Well, I thought if he can keep his cool about it, so can I.
But just between you and me, I was blazing mad.
Your posts guided me to be controlled and civil,though with great effort :) and yeah it was a compliment, even though you may not agree with it.
Happy?, lets say neutral.

Ina
Helpful - 0
Avatar universal
This may be the first time that I have been described as "diplomatic". I am not sure whether I should feel flattered or insulted but since it's you I'm happy just to be referenced. I hope you're well and happy. Mike
Helpful - 0
Avatar universal
Oy....now no sugar,does that include chocolate (lol)

I guess this news is coming at a good time, holidays & all.
I do greatly value my SVR (7 years now) but I've always thought of my little induldgence in chocolate or sugary treat's as a splurge. Something to reward myself for NOT partaking in the following~ alcohol, smokes (cigs or pot) , no fatty creamy foods, and now no/or less sugar,
so whats left....?
Sorry, as I said just venting.....

Pozzy
Helpful - 0
Avatar universal
I consider myself very realistic. I am also not as diplomatic as Mike.  I actually had to take a deep breath, or I would have exploded with anger after having read your comment about diabetics chances of achieving  SVR are being nil.
Not sure if you read a study saying so, but there is a huge difference between once chances being diminished, and being nil.

Upbeat, hmm....wrong name for somebody making such bleak statement.

Ina

Helpful - 0
Avatar universal
I agree with you - I only took exception to the word "nil". Mike
Helpful - 0
Avatar universal
This is exactly a summarized english version of the study made by doctors in Seville.
My docs didn't check my eyes (they just checked thyroid markers and insulin resistance)...they said the sugar issues are the ones that affect svr chances the most. What I didn't know was that insulin resistance increased fibrosis :-(
No wonder I have 10 KPA in my last fibroscan...
I've given up on candies and marzipan :-( and I do encourage all my heppers friends to drop sweets in all forms...and those with diabetes maybe should evaluate extending tx or exercise prior and during tx and follow and all of us shoudl manage glucose levels imho
Helpful - 0
96938 tn?1189799858
Do you know how (name of the test) that was used to test insulin resistence?  I was in Madrid a few years ago, standing beside a famous torredo (spelling?) and of course didn't realize it until I was informed later. Got the impression from my associates that this gentleman was the equivalent of a rock star or a hepatologist. He did have an entourage.
Helpful - 0
Avatar universal
How long you have had the virus isn't a factor I have heard before, maybe I am misunderstanding what you mean. What do you mean?

I contracted the virus about 7 years ago, my geno is 3a which has shown to escalate fibrosis in some and a number of other factors contributed but I haven't had it long and I am stage 3.

Others have had it 20, 30 years and are still stage 0 or 1.

Helpful - 0
Avatar universal
I am just trying to be realistic. The blood sugar is just one more thing to add to odds of SRV.  Your Geno type,  your viral load, your age,  your gender, and of course how long you have had the virus.  These all play a role in a persons chances of SVR and it seems now that diabetes also plays a role.

                                                          Ron
Helpful - 0
Avatar universal
I agree with most of what you say. I do take exception to your characterization of a person's chances of achieving SVR who has diabetes brought on by HCV as "nill". I do so in part because I am diabetic as a result of HCV and yet I am SVR. I am also a transplant recipient who was treated for acute rejection 2 or 3 times with bolus injections of Solu-Medrol and those factors don't bode well at all for one's chances at SVR. I think we should be very careful not to destroy someone's hope because in the final analysis without hope we don't have much left. And people can and do beat the odds and though I don't believe in holding out false hope I also don't believe in dashing someone's hope when there is reason for hope. I'm probably too sensitive about this but that's just the way I am. I wasn't offended by what you said - I just don't agree with it.  Mike
Helpful - 0
Avatar universal
Looks like a good wake up call to all HCV infected and during tx and post.  Fatty livers are becoming more common today and people are eating more and more and exercising less.  And it does seem like lots of people HCV also have diabetes.  I just had a good friend that treated, Stage 1,,,geno 1A, low viral load but fatty liver and overweight, borderline diabetic also. He even agrees that if he can get his weight under control,  that alone will take care of some of his other problems and then if he decided to tx again,,,better success.
Helpful - 0
Avatar universal
is a known complication of all types of liver disease, but research indicates that hepatitis C virus (HCV) infection plays a more direct role in abnormal glucose metabolism - an association that appears to differ based on HCV genotype. Studies have shown that HCV infection is associated with a higher rate of diabetes, and that blood glucose abnormalities, in turn, are linked to more severe fibrosis. Sustained responders to interferon-based therapy typically experience improved insulin sensitivity - though patients with insulin resistance are less likely to respond to anti-HCV treatment.

                                                          Ron
Helpful - 0
Avatar universal
How did you arrive at that conclusion? I just skimmed the article so if it's there I missed it and would appreciate you directing me. Mike
Helpful - 0
Avatar universal
Does this also correlate into what Scuby was saying the other day about high sugar levels maybe?

I didn't have time to read the link yet but I hope that Scuby is aware if it does!
Helpful - 0
Avatar universal
Another factor in deciding if treatment is for you. It sounds like your chances of SVR are almost nil if you have diabetes brought on by the virus.

                                                        Ron
Helpful - 0
Avatar universal
this article sounds like my situation except i'm a 2b..i finished tx in october and 6 week pcr is negative...although i dropped about 20 lbs this year on tx, i still am battling my blood sugar. i am currently taking 3 metformin daily and my sugar is still high...i have added more exercise since i finished tx and i am trying to lose more weight..hopefully my blood sugar levels will decrease.. i also have an increasingly worsening fatty liver over the past year...
                                  thanks for the post,alan
Helpful - 0
Avatar universal
thanks for the info. very helpful to me as I have both diabetes and hep c. funny when I first started treating for both I asked both doctors if they thought there was a connection of course they both said no, I guess not that funny.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.