Harvoni failure?

[48weeks]

I was just curious if any of our regulars have experienced or know of anyone who has experienced a Harvoni relapse or failure. I'm going into week 8 of 12 with good lab results and feeling good.  Again best wishes for all of us against this beast.  

[h2sguy]

I just finished 8week harvoni treatment on feb3rd....got bloodwork done on feb 4th.....my hepatology nurse phoned me today while I was at work and left a message saying my result was less than 12 viral load count, ,which is apparently common after first bloodwork....more will be revealed april 28th on my 12week post treatment bloodwork ....im praying that 8weeks was enough to cure

[Nortforky]

Sorry, I wasn't sure my initial comment had posted since I had not verified email. Don't mean to duplicate.

[Nortforky]

I just found out I have relapsed after 24 weeks on Harvoni.This was week 12 post treatment and a viral load of 1.3 million. Liver enzymes still in the normal range, but that won't last. I took my dose each day at 6am and never missed. I followed all the instructions regarding supplements and took nothing to interfere. No drinking, etc.

Harvoni thinned out my hair a little bit. I had a 12.1 fibroscan which equals f-4.
Had failed daclatasvir in clinical trial.

[nan535]

I am so sorry to hear that you relapsed after 24 weeks on Harvoni.  What genotype are you? My husband, a liver transplant patient)  just went through 24 weeks also and has finally reached SVR 12. His genotype is 1b and his viral load was 92,000 when he started. He failed two prior treatments so we were very nervous about this one.
I know how you are feeling but don't give up. Talk to your doctor and find out what he/she thinks would be best to try and get going.  Trust me, if my husband
finally got there, you can too.
Good luck!

[pacman1372]

Hello Nort , I am extremely sorry to hear about your relapse .

How soon after stopping harvoni did u relapse if i may ask !!

I am assuming that you took it for 24 weeks as stated by you above .

Best wihses and keep that hope up , there are new meds around the corner with better cure rates ..

God bless you .  

[Nortforky]

Just found out I Relapsed after 24 weeks of Harvoni. 3years ago I failed a clinical trial of Daclatasvir and Aspunaprevir.Had a breakthrough at week 20.
I was f-2 before the trial. According to a fibroscan before the Harvoni I am f-4. I asked the doctor if ribavarin would help in the last 2 months of treatment, since I was undetected and wanted to stay that way. He said there was no data on that so I didn't do it. This treatment cost me $12,000 out of pocket. I am mad and think that my treatment was not well thought out.

[flyinlynn]

So when you say you were UND at 12 weeks was that 12 weeks after your treatment ended?

Most if not all are not detected on treatment what was you post treatment testing? What tests were done at what weeks after you stopped treatment?

Thanks wishing you the best
Lynn