Aa
Aa
A
A
A
Close
Avatar universal

Having failed triple tx. Do my risks increases?

I was taken off triple therapy with incivek in week 11 with a VL of 1170. In had been 220 in week 4.  I have had hep C genotype 1A for 30 years with minimal damage and no symptoms.  Have I now awakened the sleeping giant?  Is there increased risk after failed treatment?
7 Responses
Avatar universal
No ..the fact the you treated and did not eradicate the virus will have no effect on incresed fibrosis progression other than te fact that you still have virus
.The way your liver is damaged when HCV infected is a very complex process dependant on many factors.
Studies have been done  and for the most part show no direct correlation between VL and amount of fibrosis progression (however like everything else with HCV there is some controversy on this subject also)

Basically it is the complex interrelation between the virus and your own immune response rather than the direct effect of the virus itself.

That is the very simplified version ,however there are articles and studies that have been done if you are interested in the medical jargon (linked one below)



Good luck..
Will.

http://www.turkgastro.org/text.php?id=2

1747881 tn?1546175878
More medical jargon on hep c and fibrosis progression.

http://www.hawaii.edu/hivandaids/Fibrosis%20And%20Disease%20Progression%20In%20Hepatitis%20C.pdf
Avatar universal
Hey Keith ..how ya holding up?
Will
1747881 tn?1546175878
Hey Will, I'm doing ok, definitly ready for EOT, hope all is well on planet Canada.
Avatar universal
My husband has been through three failed treatments, and each time his hepatologist has told him that she believes that treating when you have the opportunity does give your liver a break (from Hep C).
Advocate1955
Avatar universal
sorry to hear that..hopefully the liver is in good shape and you can get the next generation..I'm finishing the incivek this week , 3 days left, and I am UND- wish i could share it with you-- I hope the new PI's coming out will be more friendly to your immune system
Avatar universal
I also could not slay the dragon. I was taken off the triple treatment only after 7 weeks. I needed 3 blood transfusions and had an incident of a spontaneous pneumothorax. I have stage 2,grade 2, genotype 1b, and my viral load was 265,000 before treatment and at 4 weeks during treatment was undetectable. I have been dealing with my RA also and just seem to think that it may just be all about diet and lifestyle. If I can't treat my hep, I can't treat my RA. Any one hear about LDN?  Low Dose Naltrexone ?
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
For people with Obsessive-Compulsive Disorder (OCD), the COVID-19 pandemic can be particularly challenging.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.