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Hepatitis c occult

anyone know which is prevalence of occult hepatitis C or what is the probability to develop this form of hepatitis c
2 Responses
683231 tn?1467323017
I found this reference to a study of patients with kidney disease who are undergoing dialysis so their odds would be higher one would think than the general population from the National Center for Biotechnology Information. PubMed hope this helps answer your question. Why do you ask?


Prevalence of occult hepatitis C infection in chronic hemodialysis and kidney transplant patients.
Baid-Agrawal S, et al. J Hepatol. 2014.
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BACKGROUND & AIMS: Detection of hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells (PBMC) and/or hepatocytes in absence of HCV RNA in serum, designated as 'occult HCV infection', has been a matter of controversy in recent years. We investigated for the first time the prevalence of occult HCV infection in large cohorts of chronic hemodialysis (CHD) and kidney transplant (KTx) patients.

METHODS: We enrolled 417 CHD patients, 417 KTx recipients and 2 control groups - 25 anti-HCV (antibody against HCV)-positive and HCV RNA-positive patients with chronic hepatitis C, and 40 anti-HCV-, HCV RNA-, and HBsAg-negative healthy subjects. HCV RNA was tested in serum and PBMC using a sensitive commercial assay.

RESULTS: In CHD patients, the prevalence of anti-HCV was 3.6% (15/417) and of positive serum HCV RNA 2.4% (10/417). HCV RNA was detected in PBMC in 1/407 (0.25%) HCV serum RNA-negative patients ("occult HCV infection"). In KTx recipients, prevalence of anti-HCV was 4.8% (20/417) and of positive serum HCV RNA 4.6% (19/417). Occult HCV infection was found in 2/398 (0.5%) serum HCV RNA-negative patients. On a mean longitudinal follow-up of 30months of the 3 patients with occult HCV infection, there was no clinical or virological evidence of HCV infection.

CONCLUSIONS: The prevalence of occult HCV infection was very low in our CHD and KTx patients, and it did not appear to be clinically relevant. Further studies in geographic populations with high HCV endemicity are required to clarify the significance of occult HCV infection in these patient groups.

Copyright © 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
i need know if i have this disease yet with anti-HCV Negative
683231 tn?1467323017
If your antibody test was done 6 months after a concerning incident and the result was negative that means you do not have hep c.

The incidence of occult hep c infection per the quoted reference

"The prevalence of occult HCV infection was very low in our CHD and KTx patients, and it did not appear to be clinically relevant."

so the likelihood is very small and primarily involves patients with kidney disease who are undergoing kidney dialysis or have had a kidney transplant

Are you a kidney transplant patient or do you get kidney dialysis?

Occult hep c infection is very rare I would go with negative means negative.
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