I have been undergoing treatment for Hep C: Peg Interferon, Ribervarin and Biocipreviar. Just cleared viral load to negative at 16 weeks. ALT and AST shot up to the 300 range then 2 weeks later dropped to 150 range, this week up to 165 range. Any reason why my liver enzymes are soo high. The doc says that it happens sometimes. He did a blood test to rule out autoimmune hepatitis. They have had to adjust my thyroid meds. my TSH was way off also (31)...so they are slowley coming back down.