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How does Sovaldi work?
Now I am not in the medical field so I don't expect to understand detailed medical terminology but my curiosity is piqued. What was the breakthrough that allows Sovaldi to eradicate the virus? And to KEEP it eradicated?
In other words, at the cellular level, what did this drug do differently to kill that bugger?
If anyone knows please.. in layman's terms..
In other words, at the cellular level, what did this drug do differently to kill that bugger?
If anyone knows please.. in layman's terms..
Oh and if you want a good snooze, read this.
http://www.ncbi.nlm.nih.gov/books/NBK1630/
It just goes to show you how a few years of research can change the whole view on a disease.
http://www.ncbi.nlm.nih.gov/books/NBK1630/
It just goes to show you how a few years of research can change the whole view on a disease.
Interesting and thank you. I am still amazed that the virus does not mutate and keep growing. And more so that it does not return. I guess once the virus stops replicating it dies off and does not reoccur. I just pray some bit of it isn't hiding out in some tissue somewhere, just waiting for another opportunity to pounce..
Also this. It is hard to avoid some technical language hope this is helpful to you.
How Does Sovaldi (Sofosbuvir) Work in Hepatitis C Virus? Sovaldi (sofosbuvir), a nucleotide analogue inhibitor, acts as an imposter to trick the hepatitis C virus (HCV). Sovaldi (sofosbuvir) blocks a polymerase enzyme that plays an essential role in HCV replication. The polymerase enzyme builds new RNA genomes (the complete viral hereditary information) so that the virus can replicate. Sovaldi slips into the RNA, which prevents the virus from growing because it does not recognize Sovaldi in the RNA.
Sovaldi is known as a direct-acting agent (DAA), meaning that it interferes directly with the HCV life cycle by suppressing viral replication. Sovaldi is given as a once-a-day pill.
How Does Sovaldi (Sofosbuvir) Work in Hepatitis C Virus? Sovaldi (sofosbuvir), a nucleotide analogue inhibitor, acts as an imposter to trick the hepatitis C virus (HCV). Sovaldi (sofosbuvir) blocks a polymerase enzyme that plays an essential role in HCV replication. The polymerase enzyme builds new RNA genomes (the complete viral hereditary information) so that the virus can replicate. Sovaldi slips into the RNA, which prevents the virus from growing because it does not recognize Sovaldi in the RNA.
Sovaldi is known as a direct-acting agent (DAA), meaning that it interferes directly with the HCV life cycle by suppressing viral replication. Sovaldi is given as a once-a-day pill.
Found this
In December 2013, the FDA approved a new medication that is a part of a drug group called polymerase inhibitors. It works by blocking a specific protein the Hepatitis C virus needs to grow. It is called Sofosbuvir (brand name Sovaldi)
http://hepc.liverfoundation.org/treatment/the-basics-about-hepatitis-c-treatment/what-medications-are-used-to-treat-hepatitis-c/
hope that helps
In December 2013, the FDA approved a new medication that is a part of a drug group called polymerase inhibitors. It works by blocking a specific protein the Hepatitis C virus needs to grow. It is called Sofosbuvir (brand name Sovaldi)
http://hepc.liverfoundation.org/treatment/the-basics-about-hepatitis-c-treatment/what-medications-are-used-to-treat-hepatitis-c/
hope that helps
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