On just SOC one should be UND at week 12 for best chances of SVR and doing 48 weeks total, becoming UND between weeks 12 and 24 one should treat for 72 weeks.
I became und on SOC between weeks 16 and 24, extended tx but relapsed anyway.
The first time I was und at 12-13 week, did 32 weeks and relapsed.
However I had decompensated cirrhosis.
Now, with a healthy liver, I was und at 4 weeks.
My doc said that upped my chances of SVR.
The 240 mg arm finished that medication at 12 weeks and continued to receive all placebo. The 120 mg arm continues 120 mg until week 24.
After receiving the 'new' meds at week 12, I knew I wasn't in the 240 mg arm. I had a side effect that was unique to my morning dosage (when I take the PI pill) for me. Burning stomach. So even before receiving my PCR results from week 12, I knew I hadn't been getting the 240 mg.
I wonder if receiving the PI for 24 weeks will increase my odds of SVR, if I am receiving it...
Ah well, time will tell I suppose...
Unfortunately, it isn't my choice about how long to continue treatment. I'm in a study and I will remain on int/riba for 24, 36 or 48 weeks. I'll find this out on Jan 20.
24 is OUT. I'm at 19 weeks now and was very hopeful at the start of only doing 24... But being in a double blind study I knew there was a chance I'd have to do 48.
There is no EOT option of 72 weeks in this study. The longest is 48.
However, if I'm in the placebo arm, I'll be offered the rollover study where everyone receives the study drug. That's approximately one year away.
My week 12 result was <25. That was a 5 log drop. So I'm choosing to see the good news and won't be discouraged! :)
There are still other options available to me...