If the Hemopurifier being tested by AEMD in India is able to reduce viral loads in blood of HCV ?

[Ruffuss]

If the Hemopurifier being tested by AEMD in India is able to reduce viral loads in blood of HCV infected subjects, then how could this not be anything but helpful?
I am sure that it is not cure because not every copy of the virus is in the blood.
There are likely only a small percentage that in the blood.
But from the virus''s point of view , is it not a numbers game.
Because the reason that a person's own immune system can not rid the body of the virus is because the virus keeps mutating? The only way it can mutate is by making lose copies of it self in high numbers until one copy figures out how to defeat the immune system. Right? And then natural selection will of coarse favor that copy of that virus and it will survive and multiply until the immune system figures out how to defeat it and then the virus will have another mutant copy that natural selection will favor. And the war goes on.
At least that is how I think it works. So if a person could even reduce their viral load in there blood by 1% then
would that not decrease the odds of one of the losely made copies of the virus becoming the new mutant strain?
Of coarse if that is true then Blood letting would likely reduce the viral load in the blood by 1%.
I am not advocating the return to middle evil medicine .
But it makes so much sense to me that if the Hemopurifier does being down the load then it would definately be of great help before starting any treatment.
Unless I got it all wrong and virus's really do their thing though the aide of some sort of divine intelligence for the outside that guides their mutation.
I have no knowledge or training in medicine of any kind, so I can only look at the problem of HCV
in the way a statistic would, or a game theorist.
Can someone please straighten me out and tell me where I am wrong?

[FlGuy]

I can't help ut think that Aethlon picked the wrong disease (HCV) and at the wrong time. With drugs like teleprivir and boceprivir very close, it seems that the Hemopurifier - even if it was ever proven will be rendered obsolete for HCV in the very near future.  We have all read, and received actual patient reports, about the very fast viral effects of the new drugs even in the first few hours of administration.  Assuming that the PI's will have SOC timeframes of about 24 weeks, I don't see how AEMD would be able to carve any niche and make any inroads to the treatment of HCV.  Even if the thing works the Company management are a bunch of boob.  Good thing there aren't many of them.

AEMD's website states "...studies have confirmed the capture of Dengue Hemorrhagic Virus, Ebola Hemorrhagic Virus, Lassa Hemorrhagic Virus, West Nile Virus, H5N1 Avian Influenza Virus, 2009 H1N1 Influenza Virus, the reconstructed Spanish Flu of 1918 Virus, and Monkeypox Virus.."  If astute, it seems like the management of the company should turn it's attention to that dastardly Monkeypox virus.  If any of you recall our former member , Meki from Alaska, you might recall her references to monkey sex which she referred to on a number of occasions.  Maybe there is something there...hmmm.

Aaron was also kind enough to remind us of the Medhelp policy which includes    "ALWAYS check with your personal physician before taking any action regarding your health! "  There could be a whole bunch of people who, after reading this thread, have run to their doctors and said "hey, doc can you write me a prescription to go to Hyderbad India so I can get me Hemopurified".  It coule be, I suppose, some relief for the unemployment problem because people could get call center jobs while they are there.  Imagine, making a customer service call and getting transferred to India and actually speaking with an American.  I don't know, maybe this thing has legs after all.

Aaron also referenced the VA. The freaking VA.  The one government agency that probably creates more HCV than it cures!!

I think I'll stand by by my earlier asertion that the best course of action for AEMD might be your local Jiffy Lube location. I think it's the only way AEMD will do any business in the US.

[Trinity4]

Rubbish, the lot of it.

Trinity

[Aaron57]

This from the VA's hep website: http://www.hepatitis.va.gov/vahep?page=prtop04-wp-01

Pay particular attention to the last statement regarding beginning Tx with a high viral load and clearing the virus.........


HCV viral load. This results of this test, quantifying the amount of virus in their blood on a particular day, usually are given in "international units (IUs) per mL" and often additionally as "copies per mL." The IU measure was established to be very similar among different laboratories, so that a viral load measured in IUs by one laboratory should be equivalent to that measured by another laboratory. Values in copies/mL may vary among laboratories. Practitioners also should bear in mind that viral load often fluctuates 10-fold or more in a given patient without any clear reason.
viral loads >800,000 IU/ml or >2x106 copies/ml are considered "high."(1,2) Some laboratories will give values merely as a range (eg >800,000 IU/ml). Since a "2-log reduction" after 12 weeks of interferon therapy often requires precise knowledge of pretreatment viral load, practitioners may ask their referral laboratory to further "dilute" samples to yield an estimate of the height of viral loads outside their usual dynamic range.

"High" viral loads are associated with lower viral clearance rates in all published studies of interferon and ribavirin therapies.


All published studies of INF + Riba Tx concluded a high viral load at the start of SOC Tx lowers the clearance rates ......

nygirl - Where was it you get your data again ??

[Aaron57]

Thought this insert from MedHelp would be a good thing to remind the viewers of here:


Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.

[Aaron57]

I didn't ignore your questions, thought all the info was right in front of you, self-evident.

Your questions :

1) Are you referring to the 60 patient study that you referenced or the 9 patient study that I posted?  Those are your definition of solid reseach and proof?

Actually there is more than 100 english references I refereed you to , so yes. The most important fact is that Japanese Govt, gives financial support to their citizens who use the DFPP which was approved for HCV Tx in 2008.

If you can read Japanese you'll find thousands of references to this machine ,however that I doubt.

2) Why doesn't AEMD mount full scale independent tests like other new drugs and devices?

I'm not affiliated with AEMD , I have no idea why not ...

3) Isn't AEMD's plan to combine their device with those toxic drugs? Where is the gain there?

The gain is , if it is a success in trials like DFPP , not layering another drug on top of the SOC to achieve a high SVR ratio.

4) And make big $$$ doing it this way

Nothing in this world is free ... more power to them .


To the contributors of their valuable closed minded opinions here :

HCV virus Tx has only made small steps forward in treatment protocols in the last few years with the introduction of PI's into clinical trials ,

True or not ? This because why ?

Can you explain how INF works for some but not all ? Not likely as it's not understood yet.

For well over 15yrs. starting from the early 90's the only new introduction to the HCV Tx protocol was the Pegelated type of INF.

Recently with the industries realization of billions of $$ to made made in the next 10 yrs or more., thankfully there are steps forward in research of new protocols , PI's + we'll see what the future brings.

To discount new technology, before it has a chance to prove or disprove itself as an effective agent .......

I don't get it , how is it some of you folks think you know it all, when the doctors and scientists freely admit they don't know ??

Why would anyone want to close there mind to new technology before it could be proved or disproved?

DFPP is already and only being practiced over seas, Why only in Japan and Taiwan? I don't know the answer , it's used successfully in more ways than treating HCV as well ....
It appears those folks may well be more forward looking than the folks here ....


HemoPurifier, we'll have to wait and see what the results of their 1st clinical trials are for HCV, this info should be forth coming in the next month or so. At least they are getting their chance.

HP is not available on the market in India or anywhere else yet , only time will tell.


I really don't understand how some folks here claim to know so much, everything, regarding Tx, mutations of the virus , the effects of high or low viral load on Tx, liver regeneration, liver enzymes etc. etc.,  this list is a long one .... and yet have closed minds ......

When in the industry, research scientists, and the doctors themselves freely admit they are not even close to fully understanding what there is to know about this virus ??

[Aaron57]

your first post in response to Ruffuss's question was:

by FlGuy , Jul 21, 2010 08:43AM

Blood-letting of about 5.6 liters will resolve the HCV.  However, there are other treatments available with produce a cure in which the patient lives.

Good for you to have opened up your thinking a bit & giving link to the Energex post of 3 years ago ... !

AEMD is not doing trials or Tx in Japan , they start their clinical trials in India this month.

In Japan, DFPP is approved and successful in up to 80% of patients, the Japanese Govt. is helping patients to pay the bills when they choose to use this Tx regime.

States wise , Energex Systems has their non drug UV blood cleaning system ImmunoModulator . ( As FLGuy directed us all to )


The point is, contrary to NYGirls view of "viral load does not mean a darn thing" ,

Viral reduction at the beginning SOC Tx seems to be an effective approach for increasing the possibility of attaining SVR from 35-50% with INF + Riba alone to apx. 80% ,,, without adding any more drugs .


The DFPP approach is new , only approved in 2008 in Japan, it appears to do just as Ruffuss's question was posed, and is suggesting at the onset of this thread ....

Reducing the viral load at the beginning of SOC Tx also seems to reduce the chances of viral mutation that the virus is capable of, allowing INF+Riba to do it's job (although until now nobody can explain exactly how this happens) and achieve a much higher SVR ratio than with INF + Riba alone .


We should always get at least a second opinion if not more , when dealing with doctors ...

Doctors call their business's , even after many years of school and how ever many years they have been in business :

"Practicing" medicine

Folks, do your homework before making your personal choice. Don't just depend on what someone writes in some forum !