Aa
My virus is detected at 14 weeks
I just got my labs back today and my virus is detected I'm so angry and upset this adds to everything that's been going wrong in my life I've been unemployed for 3 months yesterday totaled my car and today get an email from health vault and I'm detected it says 180000 so it's not like its a low number:( what does this mean for me now? Am I gonna have to learn how to live with the disease I'm really heartbroken. My doctor just got the labs cause I called the nurse today and she said he hasn't reviews them but I know what I'm reading I just don't know what's next I know I failed and this is the worst news of my life
I think it is good you cried, and got it all out, that is how I deal with
disappointments also.
Were you on Triple Tx with Victrelis, or just on Interferon and Ribaviran?
Either way, the best thing is to wait for the next generation of Protease Inhibitors, rather than trying Incivek.
My husband is on a Clinical Trial, with some new meds made by AbbVie, and it is Interferon free, with very little side affects, which is a much better Treatment option!
You should look into participating in one of these "Clinical Research Trials", if they have them in your area, We live in near San Francisco, where there is a Doctor who conducts these Trial. There is also a website that can steer you to all these various Trials. They pay fairly well, also~
I think the link is something like "clinicaltrials.gov", then when you get there, you put "Hep C" in the search engine, etc.
There is tons of stress with this journey, but you did everything right. Dont think of it as you "failing" the Treatment, think of it as the Treatment not working for you. Some people just dont respond well to Interferon, thus the relapse. That is why there is so much hope for you and other Heppers, because the new meds will be Interferon free.
Stay brave, and keep up the good fight~ There are so many diseases out there that have no cure, so I suppose we are "lucky" to have a disease where HUGE progress is being made, in finding a perfect cure.
Stick around, and you will remain well-educated, and that is your best defense!
disappointments also.
Were you on Triple Tx with Victrelis, or just on Interferon and Ribaviran?
Either way, the best thing is to wait for the next generation of Protease Inhibitors, rather than trying Incivek.
My husband is on a Clinical Trial, with some new meds made by AbbVie, and it is Interferon free, with very little side affects, which is a much better Treatment option!
You should look into participating in one of these "Clinical Research Trials", if they have them in your area, We live in near San Francisco, where there is a Doctor who conducts these Trial. There is also a website that can steer you to all these various Trials. They pay fairly well, also~
I think the link is something like "clinicaltrials.gov", then when you get there, you put "Hep C" in the search engine, etc.
There is tons of stress with this journey, but you did everything right. Dont think of it as you "failing" the Treatment, think of it as the Treatment not working for you. Some people just dont respond well to Interferon, thus the relapse. That is why there is so much hope for you and other Heppers, because the new meds will be Interferon free.
Stay brave, and keep up the good fight~ There are so many diseases out there that have no cure, so I suppose we are "lucky" to have a disease where HUGE progress is being made, in finding a perfect cure.
Stick around, and you will remain well-educated, and that is your best defense!
My trial was only 12 weeks and my side effects were mild headache, insomnia and a little Diarrhea which they subsided after about the first month. Nothing really.
Stage 1 and 22 years old your in very good shape. I would have the Doc do another PCR just to make sure and if it did return just wait. If your Doctor is any good he'll tell you the same thing. In the mean time no drinking and try not to stress. These drugs are for real and getting very close to being for everybody. I just finished a trial with the BMS all oral drugs, no interferon or ribavirin. I was undetected before my second week and stayed undetected, I am 6 weeks post treatment and just got my 4 week post results and I am still undetected. Your going to be ok, REALLY.
Bob
Bob
Best wishes to you Jackelyn. You have been fighting a good fight and it is not over. I believe you have some great options ahead of you. Let us know how your retest goes and what your doc's input is. You were one of the first to welcome me to the forum and I appreciate that because your attitude toward your tx gave me great inspiration. Keep your chin up! Everything will be okay!
Oh yes and I have had a biopsy already before I started treatment stage 1 I believe I really hope I won't have to do that again
Hey everybody thank you so much for the support I cried all day yesterday so I think I got it all out I already have a lab order for another PCr cause my doctor gave me 2 since I was late to the appointment so ill go get that done Monday. I'm 22 years old and have geno type 1 I'm happy to hear there's other meds out there that are helping that really gave me some hope I know times on my side as you guys know its still so upsetting but ill make it through! I've learned a lot through this little time of treatment and ill stay in touch it would be a miracle if the test was false but I've already accepted that its probably not I will let everyone know.
Jackelyn, so sorry to here this news... and you sound down which is natural. Do as suggested and confirm with another test. If positive, please try and keep your head up as by considering the previous posters points: that you have a very little damage now with years (decades if need be) to await better drugs (I'm at stage 3 but have probably had it for 40 years). Also, read a study which mentioned breakthroughs then to get high VL but typically return to their previous pre-treatment levels (can't recall the time lag though). Sadness and disappointment would be only natural, but don't let the interferon depression get the better of you. This is a set back, not the end and time is on your side.
jackelyn what Genotype are you and have you had a Biopsy, if so what's your liver condition? These new drugs from Gilead,BMS and Abbott are working miracles. Gilead will have approval for types 2 & 3 by December with Ribavirin and types 1,4,5 & 6 with Interferon. 2014 looks like the will all be approved for all Genotypes without Interferon and maybe without the Ribavirin. If your liver is not too bad you'll be fine. I can only imagine how it must feel to have a break through but you don't have to live with it there is some awesome stuff just off the horizon.
Bob
Bob
I am sorry I did not say this in my last post. I, too, am very sorry you are going through this. It is very stressful and devastating.
Please do keep us informed. We do care.
Please do keep us informed. We do care.
I am sorry you are going through this! Listen to all the above advice they know what they are talking about. I hope it's a lab error but if it's any consolation you are lucky to have only minimal fibrosis. So you do have time to treat in the future. Most of us weren't that lucky and had to make decisions immediately to treat. Hang in there and keep in touch!
Jules :)
Jules :)
Hi Jacke. I'm really sorry your seeing this on your labs. I would really call your doctor or wait to hear the results directly from your doctor. This could be an error and if it was me.... I would want a retest to confirm the results.
My Hearts With You
My Hearts With You
I agree with the others who said to get a redraw just to be sure that there was not a lab error.
If that test confirms that you are DET again, then you have had a viral breakthrough (as mentioned above).
You asked if you can do the triple with the Incivek. That would NOT be recommended. The Victrelis and the Incivek are very similar, both being protease inhibitors, and if one did not work, the other probably will not work. It is NOT recommended to try the other if one of them fails.
The other thing is, if you did have a viral breakthrough, the reason is usually due to a person NOT being responsive to Interferon. Therefore, as mentioned above, you probably need to wait for treatment which is not Interferon based.
This is not your fault. It happens, even when one does everything right and has not deviated from the treatment protocol.
The good thing is, you do not have much liver damage, if any, and therefore you do actually have some breathing room in terms of treatment. There will be new Interferon free treatments out in the future. Since you are Stage 0-1, you should have time to treat in the future before you progress to advanced fibrosis.
However, I would still get a recheck just to be sure there is no lab error.
I am posting a link to Dr. Jean-Michel Pawlotky's presentation about resistance issues. It is an excellent presentation and I think you will find that it clearly explains what has happened in your situation.
http://74.43.177.57/courses/2010/pg/pawlotsky/player.html
If that test confirms that you are DET again, then you have had a viral breakthrough (as mentioned above).
You asked if you can do the triple with the Incivek. That would NOT be recommended. The Victrelis and the Incivek are very similar, both being protease inhibitors, and if one did not work, the other probably will not work. It is NOT recommended to try the other if one of them fails.
The other thing is, if you did have a viral breakthrough, the reason is usually due to a person NOT being responsive to Interferon. Therefore, as mentioned above, you probably need to wait for treatment which is not Interferon based.
This is not your fault. It happens, even when one does everything right and has not deviated from the treatment protocol.
The good thing is, you do not have much liver damage, if any, and therefore you do actually have some breathing room in terms of treatment. There will be new Interferon free treatments out in the future. Since you are Stage 0-1, you should have time to treat in the future before you progress to advanced fibrosis.
However, I would still get a recheck just to be sure there is no lab error.
I am posting a link to Dr. Jean-Michel Pawlotky's presentation about resistance issues. It is an excellent presentation and I think you will find that it clearly explains what has happened in your situation.
http://74.43.177.57/courses/2010/pg/pawlotsky/player.html
It's really time to talk to your doctor about stopping treatment. anytime one has a break through treatment should be halted. As desrt said above there are new meds in the pipeline...... Sorry you had to go through this but time is on your side........ Wishing you the best.
Oh okay..sorry about my misunderstanding from the posts. Don't give give up yet. Try to stay calm and wait until your doc has time to review and go over with you. Sounds like you have done everything right and are giving it your all.
No he's doing it right I was suppose to get my labs done at week twelve but couldn't make it to the docs till a week and a half later so I'm just getting the labs now I just don't understand how this could happen I've been doing everything the same? What about the triple treatment with the inkevik can't I do that? I guess it is what it is I'm used to things going wrong just feel like I wanted so much time
I hope this is a mistake. I agree I would ask for another test. If I'm not mistaken it seems that you had a testing protocol issue when they didn't do a 4 week PCR if I remember from one of your posts. I'm curious why they haven't followed a 4 week, then 12 week check (why an 8 and 14). Again, I may have misinterpreted your past posts but if this protocol was followed, I would question it and retest.
If the test is correct, yes this is breakthrough. It just means you'll probably have to wait for a non-IFN based tx.
I would ask for a confirming test just to make sure it wasn't a skrew up by the lab.
I would ask for a confirming test just to make sure it wasn't a skrew up by the lab.
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